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In wheat,\n                    <jats:italic>TaPR1\u20102<\/jats:italic>\n                    has been widely used as a molecular marker of immune responses to rust fungi. However, it remains unclear whether other members of the PR1 family are involved in wheat resistance to leaf rust. Here, we show that the transcript levels of\n                    <jats:italic>TaPR1\u201011<\/jats:italic>\n                    are induced following inoculation with\n                    <jats:italic>Puccinia triticina<\/jats:italic>\n                    (\n                    <jats:italic>Pt<\/jats:italic>\n                    ). Overexpression of\n                    <jats:italic>TaPR1\u201011<\/jats:italic>\n                    significantly enhanced wheat resistance to\n                    <jats:italic>Pt<\/jats:italic>\n                    , accompanied by reduced fungal growth, whereas\n                    <jats:italic>TaPR1\u201011<\/jats:italic>\n                    \u2010RNAi wheat lines displayed increased susceptibility. TaPR1\u201011 physically interacts with TaPR4\u20101, a Barwin\u2010like protein that also positively regulates wheat resistance to\n                    <jats:italic>Pt<\/jats:italic>\n                    . Further analysis revealed that TaPR1\u201011 stabilizes TaPR4\u20101 in vivo, while TaPR4\u20101 reciprocally promotes TaPR1\u201011 protein accumulation during\n                    <jats:italic>Pt<\/jats:italic>\n                    infection. Collectively, our findings identify a previously unreported PR1\u2010PR4 protein partnership in wheat, showing that TaPR1\u201011 stabilizes TaPR4\u20101 to enhance resistance against\n                    <jats:italic>Pt<\/jats:italic>\n                    . This work expands current understanding of the molecular mechanisms by which PR1 proteins contribute to wheat defence responses.\n                  <\/jats:p>","DOI":"10.1111\/pce.70643","type":"journal-article","created":{"date-parts":[[2026,5,29]],"date-time":"2026-05-29T11:53:39Z","timestamp":1780055619000},"page":"6521-6532","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["A PR1\u2010Like Protein Stabilizes a Barwin\u2010Like Protein to Enhance Wheat Resistance to Leaf Rust"],"prefix":"10.1111","volume":"49","author":[{"given":"Huan","family":"Peng","sequence":"first","affiliation":[{"name":"State Key Laboratory for Crop Stress Resistance and High\u2010Efficiency Production, College of Plant Protection Northwest A&amp;F University Yangling Shaanxi China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ke","family":"Zhang","sequence":"additional","affiliation":[{"name":"State Key Laboratory for Crop Stress Resistance and High\u2010Efficiency Production, College of Plant Protection Northwest A&amp;F University Yangling Shaanxi China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Li","family":"Geng","sequence":"additional","affiliation":[{"name":"State Key Laboratory for Crop Stress Resistance and High\u2010Efficiency Production, College of Plant Protection Northwest A&amp;F University Yangling Shaanxi China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hongyan","family":"Wang","sequence":"additional","affiliation":[{"name":"State Key Laboratory for Crop Stress Resistance and High\u2010Efficiency Production, College of Plant Protection Northwest A&amp;F University Yangling Shaanxi China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jinbiao","family":"Ma","sequence":"additional","affiliation":[{"name":"State Key Laboratory of Desert and Oasis Ecology Key Laboratory of Ecological Safety and Sustainable Development in Arid 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