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E3 ubiquitin ligases are central regulators of protein turnover in signaling pathways, but their roles in the plant circadian system have yet to be fully elucidated. In this study, we find that the transcript of E3 ligase CCRG1 shows diurnal rhythmicity and sustained oscillation under continuous light in\n                    <jats:italic>Arabidopsis thaliana<\/jats:italic>\n                    . Molecular analyses demonstrate that the core clock components LATE ELONGATED HYPOCOTYL (LHY) and CIRCADIAN CLOCK ASSOCIATED 1 (CCA1) directly regulate\n                    <jats:italic>CCRG1<\/jats:italic>\n                    transcription through promoter binding. The\n                    <jats:italic>ccrg1<\/jats:italic>\n                    single mutants exhibit an increase in vegetative growth compared with the wild\u2010type plants. The introduction of\n                    <jats:italic>CCRG1<\/jats:italic>\n                    mutation in the\n                    <jats:italic>cca1 lhy<\/jats:italic>\n                    double mutants significantly suppresses the developmental defects, restoring vegetative biomass and alleviating premature flowering and leaf senescence. Furthermore,\n                    <jats:italic>CCA1<\/jats:italic>\n                    <jats:sub>\n                      <jats:italic>pro<\/jats:italic>\n                    <\/jats:sub>\n                    <jats:italic>::CCRG1<\/jats:italic>\n                    lines in the Col\u20100 background showed modestly elevated morning\n                    <jats:italic>CCRG1<\/jats:italic>\n                    expression without an obvious phase shift and exhibited delayed bolting. Together, our findings establish CCRG1 as a transcriptionally regulated ubiquitination node downstream of the morning oscillator, linking core clock regulation to specific developmental outputs and revealing an additional layer of circadian\u2010controlled protein regulation in plants.\n                  <\/jats:p>","DOI":"10.1111\/pce.70696","type":"journal-article","created":{"date-parts":[[2026,6,24]],"date-time":"2026-06-24T07:07:51Z","timestamp":1782284871000},"page":"7238-7251","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["CCRG1 Acts as a Downstream Effector of the Clock Proteins CCA1 and LHY to Coordinate Growth, Flowering, and Senescence"],"prefix":"10.1111","volume":"49","author":[{"given":"Yingying","family":"Liu","sequence":"first","affiliation":[{"name":"Key Laboratory of Bio\u2010Resources and Eco\u2010Environment of Ministry of Education College of Life Sciences, Sichuan University Chengdu 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