{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,8]],"date-time":"2026-10-08T06:51:44Z","timestamp":1791442304841,"version":"4.3.3"},"reference-count":55,"publisher":"Wiley","issue":"11","license":[{"start":{"date-parts":[[2026,7,9]],"date-time":"2026-07-09T00:00:00Z","timestamp":1783555200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2026,7,9]],"date-time":"2026-07-09T00:00:00Z","timestamp":1783555200000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"funder":[{"DOI":"10.13039\/501100004731","name":"Natural Science Foundation of Zhejiang Province","doi-asserted-by":"publisher","award":["LQ24C130003"],"award-info":[{"award-number":["LQ24C130003"]}],"id":[{"id":"10.13039\/501100004731","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Plant Cell &amp; Environment"],"published-print":{"date-parts":[[2026,11]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:p>\n                    Seed dormancy is a complex developmental and agronomic trait requiring a delicate balance: insufficient dormancy leads to pre\u2010harvest sprouting (PHS), while excessive dormancy causes uneven germination. Understanding the intrinsic mechanisms resolving this trade\u2010off is vital for crop improvement. In this study, our findings indicate that the heat shock transcription factor OsHsfA2a acts as a negative regulator of seed dormancy. The\n                    <jats:italic>hsfa2a<\/jats:italic>\n                    knockout mutants exhibited enhanced PHS resistance while maintaining yield potential and post\u2010harvest germination rates, offering a potential strategy to uncouple PHS resistance from agronomic penalties. Mechanistically, our data suggest that OsHsfA2a self\u2010associates and can activate the ABA catabolic gene\n                    <jats:italic>OsABA8ox3<\/jats:italic>\n                    , thereby promoting dormancy release. Furthermore, genetic analysis using the\n                    <jats:italic>sd6 hsfa2a<\/jats:italic>\n                    double mutant supports the hypothesis that the bHLH transcription factor OsSD6 is epistatic to OsHsfA2a, acting as an upstream initiator. Biochemically, OsSD6 transcriptionally activates\n                    <jats:italic>OsHsfA2a<\/jats:italic>\n                    . Once expressed, OsHsfA2a likely amplifies the signal via a self\u2010activation loop. However, the accumulating OsSD6 protein physically interacts with OsHsfA2a, which we propose competitively attenuates its DNA\u2010binding capacity. These results support a multi\u2010tiered regulatory module operating across both transcriptional and post\u2010translational levels. Collectively, our findings provide insights into an intrinsic physiological mechanism by which this module fine\u2010tunes ABA catabolism to govern primary seed dormancy, providing precise genetic targets for mitigating PHS.\n                  <\/jats:p>","DOI":"10.1111\/pce.70703","type":"journal-article","created":{"date-parts":[[2026,7,9]],"date-time":"2026-07-09T16:12:08Z","timestamp":1783613528000},"page":"8150-8165","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["The Heat Shock Transcription Factor OsHsfA2a Modulates Rice Seed Dormancy and Pre\u2010Harvest Sprouting With OsSD6"],"prefix":"10.1111","volume":"49","author":[{"given":"Zhang","family":"Dong","sequence":"first","affiliation":[{"name":"Zhejiang Key Laboratory of Crop Germplasm Innovation and Utilization, Institute of Crop Science College of Agriculture and Biotechnology, Zhejiang University Hangzhou Zhejiang Province China"},{"name":"Hainan Research Institute Zhejiang University Sanya Hainan Province China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiaobo","family":"Zhu","sequence":"additional","affiliation":[{"name":"Zhejiang Key Laboratory of Crop Germplasm Innovation and Utilization, Institute of Crop Science College of Agriculture and Biotechnology, Zhejiang University Hangzhou Zhejiang Province China"},{"name":"Hainan Research Institute Zhejiang University Sanya Hainan Province China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Haoyuan","family":"Chen","sequence":"additional","affiliation":[{"name":"Zhejiang Key Laboratory of Crop Germplasm Innovation and Utilization, Institute of Crop Science College of Agriculture and Biotechnology, Zhejiang University Hangzhou Zhejiang Province China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yihan","family":"Liu","sequence":"additional","affiliation":[{"name":"Zhejiang Key Laboratory of Crop Germplasm Innovation and 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