{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,8]],"date-time":"2026-10-08T06:52:03Z","timestamp":1791442323617,"version":"4.3.3"},"reference-count":36,"publisher":"Wiley","issue":"11","license":[{"start":{"date-parts":[[2026,7,28]],"date-time":"2026-07-28T00:00:00Z","timestamp":1785196800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2026,7,28]],"date-time":"2026-07-28T00:00:00Z","timestamp":1785196800000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"funder":[{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["31871963"],"award-info":[{"award-number":["31871963"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Plant Cell &amp; Environment"],"published-print":{"date-parts":[[2026,11]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:p>\n                    Studies indicate that elevated CO\n                    <jats:sub>2<\/jats:sub>\n                    (eCO\n                    <jats:sub>2<\/jats:sub>\n                    ) can exacerbate the damage caused by brown planthopper\n                    <jats:italic>Nilaparvata lugens<\/jats:italic>\n                    to rice plants compared to ambient CO\n                    <jats:sub>2<\/jats:sub>\n                    (aCO\n                    <jats:sub>2<\/jats:sub>\n                    ), though the underlying mechanism remains unclear. In this study, targeted metabonomics analysis showed that the differential secondary metabolites of rice plants under aCO\n                    <jats:sub>2<\/jats:sub>\n                    and eCO\n                    <jats:sub>2<\/jats:sub>\n                    were mainly enriched in the \u201cflavone and flavonol biosynthesis\u201d pathway, and the contents of six flavones (i.e., apigenin, apigetrin, cynaroside, luteolin, orientin and rhoifolin) that could stimulate\n                    <jats:italic>N. lugens<\/jats:italic>\n                    feeding were significantly increased in rice plants under eCO\n                    <jats:sub>2<\/jats:sub>\n                    . Meanwhile, knockdown of\n                    <jats:italic>OBP7<\/jats:italic>\n                    of\n                    <jats:italic>N. lugens<\/jats:italic>\n                    markedly reduced this feeding stimulation. In vitro fluorescence competitive binding assays verified the specific binding between OBP7 and feeding\u2010stimulating flavones. Molecular docking and site\u2010directed mutagenesis further identified Gly132, Gly135, His136 and Glu137 as essential residues mediating OBP7\u2010flavone interactions. Additionally, virtual screening and functional validation identified benzoylpaeoniflorin as a competitive inhibitor of OBP7\u2010flavones, suppressing feeding and inducing oxidative stress in\n                    <jats:italic>N. lugens<\/jats:italic>\n                    . Exogenous application of benzoylpaeoniflorin effectively mitigated the aggravating damage of\n                    <jats:italic>N. lugens<\/jats:italic>\n                    to rice plants under eCO\n                    <jats:sub>2<\/jats:sub>\n                    . These findings elucidate how OBP7 in\n                    <jats:italic>N. lugens<\/jats:italic>\n                    senses eCO\n                    <jats:sub>2<\/jats:sub>\n                    \u2010induced flavones to aggravate herbivory, offering novel pest control strategies under climate change scenarios.\n                  <\/jats:p>","DOI":"10.1111\/pce.70783","type":"journal-article","created":{"date-parts":[[2026,7,28]],"date-time":"2026-07-28T10:26:48Z","timestamp":1785234408000},"page":"8683-8696","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Odorant\u2010Binding Protein Can Mediate Flavones Perception in Rice Planthopper to Exacerbate the Damage Under Elevated CO\n                    <sub>2<\/sub>"],"prefix":"10.1111","volume":"49","author":[{"given":"Ruichuan","family":"Duan","sequence":"first","affiliation":[{"name":"State Key Laboratory of Agricultural and Forestry Biosecurity, Department of Entomology College of Plant Protection, Nanjing Agricultural University Nanjing China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xinru","family":"Xiao","sequence":"additional","affiliation":[{"name":"State Key Laboratory of Agricultural and Forestry Biosecurity, Department of Entomology College of Plant Protection, Nanjing Agricultural University Nanjing China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shuqi","family":"Ren","sequence":"additional","affiliation":[{"name":"State Key Laboratory of Agricultural and Forestry Biosecurity, Department of Entomology College of Plant Protection, Nanjing Agricultural University Nanjing China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yewei","family":"Jia","sequence":"additional","affiliation":[{"name":"State Key Laboratory of Agricultural and Forestry Biosecurity, Department of Entomology College of Plant Protection, Nanjing Agricultural University Nanjing China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7011-1318","authenticated-orcid":false,"given":"Guijun","family":"Wan","sequence":"additional","affiliation":[{"name":"State Key Laboratory of Agricultural and Forestry Biosecurity, Department of Entomology College of Plant Protection, Nanjing Agricultural University Nanjing China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0770-8090","authenticated-orcid":false,"given":"Fajun","family":"Chen","sequence":"additional","affiliation":[{"name":"State Key Laboratory of Agricultural and Forestry Biosecurity, Department of Entomology College of Plant Protection, Nanjing Agricultural University Nanjing China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,7,28]]},"reference":[{"key":"e_1_2_8_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jhazmat.2020.122720"},{"key":"e_1_2_8_3_1","doi-asserted-by":"publisher","DOI":"10.1111\/febs.15708"},{"key":"e_1_2_8_4_1","doi-asserted-by":"publisher","DOI":"10.1093\/jee\/toad091"},{"key":"e_1_2_8_5_1","first-page":"279","article-title":"An Experimental Instrument to Study the Effects of Changes in CO2 Concentrations on the Interactions Between Plants and insects\u2010CDCC\u20101 Chamber","volume":"41","author":"Chen F. 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