{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,24]],"date-time":"2026-08-24T06:20:10Z","timestamp":1787552410806,"version":"build-2736575974"},"reference-count":50,"publisher":"Wiley","license":[{"start":{"date-parts":[[2026,8,23]],"date-time":"2026-08-23T00:00:00Z","timestamp":1787443200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"},{"start":{"date-parts":[[2026,8,23]],"date-time":"2026-08-23T00:00:00Z","timestamp":1787443200000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Plant Cell &amp;amp; Environment"],"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:p>Plants frequently encounter multiple pathogens concurrently, yet the molecular bases of pathogen\u2013pathogen interactions during mixed infections remain largely unresolved. Here we show that co\u2010infection of rice by Rice orange leaf phytoplasma (ROLP) and Rice stripe mosaic virus (RSMV) markedly suppresses RSMV proliferation in both host plants and the insect vector. Electron microscopy and confocal imaging reveal that ROLP and RSMV co\u2010inhabit individual rice phloem cells and undergo close membrane interaction, producing swollen RSMV virions with reduced infectivity. We further demonstrate that the ROLP membrane protein Imp interacts with the RSMV G envelope protein and competitively disrupts the G\u2013M association essential for virion assembly. The Imp region encompassing residues 96\u2013122 (Imp\u2010\u03b14) is necessary for this inhibition. Transgenic rice overexpressing Imp or Imp\u2010\u03b14 phenocopies these effects, displaying deformed virions and diminished viral load. These findings uncover a cross\u2010kingdom antagonistic mechanism between two phylogenetically distant pathogens and offer conceptual directions for engineering durable antiviral resistance.<\/jats:p>","DOI":"10.1111\/pce.70839","type":"journal-article","created":{"date-parts":[[2026,8,24]],"date-time":"2026-08-24T05:40:06Z","timestamp":1787550006000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Rice Orange Leaf Phytoplasma Imp Protein Blocks G\u2013M Interaction by Binding Glycoprotein G to Suppress Rice Stripe Mosaic Virus Infection"],"prefix":"10.1111","author":[{"given":"Jiaxin","family":"Qiu","sequence":"first","affiliation":[{"name":"State Key Laboratory of Agriculture and Forestry Biosecurity, Institute of Plant Virology Fujian Agriculture and Forestry University Fuzhou Fujian China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yujiao","family":"Zheng","sequence":"additional","affiliation":[{"name":"State Key Laboratory of Agriculture and Forestry Biosecurity, Institute of Plant Virology Fujian Agriculture and Forestry University Fuzhou Fujian China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yanmei","family":"Yi","sequence":"additional","affiliation":[{"name":"State Key Laboratory of Agriculture and Forestry Biosecurity, Institute of Plant Virology Fujian Agriculture and Forestry University Fuzhou Fujian China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yuxin","family":"Zhang","sequence":"additional","affiliation":[{"name":"State Key Laboratory of Agriculture and Forestry Biosecurity, Institute of Plant Virology Fujian Agriculture and Forestry University Fuzhou Fujian China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tianbao","family":"Zeng","sequence":"additional","affiliation":[{"name":"State Key Laboratory of Agriculture and Forestry Biosecurity, Institute of Plant Virology Fujian Agriculture and Forestry University Fuzhou Fujian China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hongyan","family":"Chen","sequence":"additional","affiliation":[{"name":"State Key Laboratory of Agriculture and Forestry Biosecurity, Institute of Plant Virology Fujian Agriculture and Forestry University Fuzhou Fujian China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Taiyun","family":"Wei","sequence":"additional","affiliation":[{"name":"State Key Laboratory of Agriculture and Forestry Biosecurity, Institute of Plant Virology Fujian Agriculture and Forestry University Fuzhou Fujian China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1763-1154","authenticated-orcid":false,"given":"Xiao\u2010Feng","family":"Zhang","sequence":"additional","affiliation":[{"name":"State Key Laboratory of Agriculture and Forestry Biosecurity, Institute of Plant Virology Fujian Agriculture and Forestry University Fuzhou Fujian China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,8,23]]},"reference":[{"key":"e_1_2_8_2_1","doi-asserted-by":"crossref","first-page":"313","DOI":"10.1094\/PDIS-06-24-1332-RE","article-title":"Inter\u2010 and Intrapathogen Interactions Emanating From Coinfection With Different Fungal and Viral Strains in Canola Cultivars With Differing Host Resistances","volume":"109","author":"Abidin N.","year":"2025","journal-title":"Plant Disease"},{"key":"e_1_2_8_3_1","doi-asserted-by":"crossref","DOI":"10.1016\/j.micpath.2022.105596","article-title":"Preponderance of Mixed Infection of Cucumber Mosaic Virus and Candidatus Phytoplasma Australasia on Brinjal in India","volume":"169","author":"Abirami R.","year":"2022","journal-title":"Microbial Pathogenesis"},{"key":"e_1_2_8_4_1","first-page":"145","volume-title":"Chapter Five\u2014Implications of Mixed Viral Infections on Plant Disease Ecology and Evolution","author":"Alcaide C.","year":"2020"},{"key":"e_1_2_8_5_1","doi-asserted-by":"crossref","first-page":"281","DOI":"10.3390\/insects14030281","article-title":"Potato (Solanum tuberosum) as a New Host for Pentastiridius leporinus (Hemiptera: Cixiidae) and Candidatus Arsenophonus Phytopathogenicus","volume":"14","author":"Behrmann S. 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