{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,9]],"date-time":"2026-10-09T12:56:24Z","timestamp":1791550584197,"version":"4.3.4"},"reference-count":61,"publisher":"Wiley","license":[{"start":{"date-parts":[[2026,10,9]],"date-time":"2026-10-09T00:00:00Z","timestamp":1791504000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2026,10,9]],"date-time":"2026-10-09T00:00:00Z","timestamp":1791504000000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Plant Cell &amp;amp; Environment"],"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:p>The plant plasma membrane is a chemically asymmetric, mechanically coupled and actively renewed interface in which lipids, receptors, ion channels, transporters and scaffolds form transient nanoscale assemblies. Direct evidence from a limited number of plant systems shows that membrane organisation can alter protein mobility, trafficking and physiological output, including remorin\u2010dependent PIN2 hyperclustering, phosphatidylserine\u2010dependent ROP6 nano\u2010organisation and stimulus\u2010dependent receptor or channel redistribution. These findings do not establish a universal molecular network or a direct route from nanodomain state to whole\u2010plant acclimation. Here, we define the adaptive plasma\u2010membrane nanodomain code as a testable, context\u2010dependent relationship between measured organisational variables \u2013 size, density, stoichiometry, diffusion, residence time, lipid dependence and trafficking flux \u2013 and specified biochemical or physiological outputs under matched protein abundance. We synthesise evidence from remorins, flotillins, receptor kinases, mechanosensitive channels and PIN auxin transporters, while distinguishing demonstrated findings from mechanistic inference and prediction. We also examine how temperature, water deficit, salinity, pH, reactive oxygen species, pathogens and hormones may reshape nanoscale organisation under constraints imposed by the cell wall, cortical cytoskeleton, endocytosis and ER\u2013plasma\u2010membrane contact sites. Finally, we propose falsifiable experiments and crop\u2010engineering strategies centred on inducible threshold tuning rather than constitutive pathway activation.<\/jats:p>","DOI":"10.1111\/pce.70966","type":"journal-article","created":{"date-parts":[[2026,10,9]],"date-time":"2026-10-09T12:40:22Z","timestamp":1791549622000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Adaptive Plasma\u2010Membrane Nanodomains in Plants: Integrating Lipids, Receptors, Mechanics and Trafficking During Stress"],"prefix":"10.1111","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-0696-3057","authenticated-orcid":false,"given":"Sajid","family":"Ali","sequence":"first","affiliation":[{"name":"Department of Horticulture and Life Science Yeungnam University Gyeongsan South Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5486-4408","authenticated-orcid":false,"given":"Muhammad Saeed","family":"Akhtar","sequence":"additional","affiliation":[{"name":"Department of Chemistry Yeungnam University Gyeongsan South 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