{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,7]],"date-time":"2026-10-07T15:49:55Z","timestamp":1791388195869,"version":"4.3.3"},"reference-count":39,"publisher":"Wiley","license":[{"start":{"date-parts":[[2026,10,7]],"date-time":"2026-10-07T00:00:00Z","timestamp":1791331200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2026,10,7]],"date-time":"2026-10-07T00:00:00Z","timestamp":1791331200000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"funder":[{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["32400558"],"award-info":[{"award-number":["32400558"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["32170585"],"award-info":[{"award-number":["32170585"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Plant Cell &amp;amp; Environment"],"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:p>\n                    The timing of the vegetative\u2010to\u2010reproductive transition is critical for plant reproductive success. In\n                    <jats:italic>Arabidopsis<\/jats:italic>\n                    , the B\u2010box transcription factor CONSTANS (CO) is a central regulator of flowering that activates\n                    <jats:italic>FLOWERING LOCUS T<\/jats:italic>\n                    (\n                    <jats:italic>FT<\/jats:italic>\n                    ). Although the transcriptional regulation and post\u2010translational stability of CO have been extensively characterised, the mechanisms governing its nuclear accumulation remain poorly defined. Here, we identify IMPORTIN \u03b24 (IMB4) as a positive regulator of flowering time. Loss of IMB4 delayed flowering and reduced\n                    <jats:italic>FT<\/jats:italic>\n                    expression without affecting\n                    <jats:italic>CO<\/jats:italic>\n                    transcript abundance. IMB4 interacts with the C\u2010terminal CCT domain of CO, promoted its nuclear accumulation, and thereby enables efficient\n                    <jats:italic>FT<\/jats:italic>\n                    activation. IMB4 and CO show coincident diurnal expression peaks at dusk, suggesting temporal coordination of this transport step. Together, these findings identified IMB4 as a regulator of the CO\u2010FT module and support a role for nucleocytoplasmic partitioning in flowering\u2010time regulation.\n                  <\/jats:p>","DOI":"10.1111\/pce.70969","type":"journal-article","created":{"date-parts":[[2026,10,7]],"date-time":"2026-10-07T14:51:11Z","timestamp":1791384671000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["IMPORTIN \u03b24 Facilitates CONSTANS Nuclear Accumulation and\n                    <i>FT<\/i>\n                    Activation in\n                    <i>Arabidopsis<\/i>"],"prefix":"10.1111","author":[{"ORCID":"https:\/\/orcid.org\/0009-0002-6649-3592","authenticated-orcid":false,"given":"Yuanda","family":"Wang","sequence":"first","affiliation":[{"name":"Joint Centre for Single Cell Biology, School of Agriculture and Biology Shanghai Jiao Tong University Shanghai China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yiyao","family":"Xu","sequence":"additional","affiliation":[{"name":"Joint Centre for Single Cell Biology, School of Agriculture and Biology Shanghai Jiao Tong University Shanghai China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zhili","family":"Deng","sequence":"additional","affiliation":[{"name":"Joint Centre for Single Cell Biology, School of Agriculture and Biology Shanghai Jiao Tong University Shanghai China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chunmei","family":"Yin","sequence":"additional","affiliation":[{"name":"Joint Centre for Single Cell Biology, School of Agriculture and Biology Shanghai Jiao Tong University Shanghai China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1744-7928","authenticated-orcid":false,"given":"Yuda","family":"Fang","sequence":"additional","affiliation":[{"name":"Joint Centre for Single Cell Biology, School of Agriculture and Biology Shanghai Jiao Tong University Shanghai China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,10,7]]},"reference":[{"key":"e_1_2_8_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ceb.2021.01.006"},{"key":"e_1_2_8_3_1","doi-asserted-by":"publisher","DOI":"10.1038\/nrg3291"},{"key":"e_1_2_8_4_1","doi-asserted-by":"publisher","DOI":"10.1111\/tpj.14796"},{"key":"e_1_2_8_5_1","doi-asserted-by":"publisher","DOI":"10.1111\/jipb.13540"},{"key":"e_1_2_8_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.devcel.2018.01.027"},{"key":"e_1_2_8_7_1","doi-asserted-by":"publisher","DOI":"10.1105\/tpc.16.00864"},{"key":"e_1_2_8_8_1","doi-asserted-by":"crossref","first-page":"25","DOI":"10.1111\/nph.14756","article-title":"The Nuclear Pore Complex: A Strategic Platform for Regulating Cell Signaling","volume":"219","author":"Gu Y.","year":"2017","journal-title":"New Phytologist"},{"key":"e_1_2_8_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.molp.2017.09.008"},{"key":"e_1_2_8_10_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10059-011-2321-7"},{"key":"e_1_2_8_11_1","doi-asserted-by":"publisher","DOI":"10.1038\/emboj.2008.68"},{"key":"e_1_2_8_12_1","doi-asserted-by":"publisher","DOI":"10.7554\/eLife.21184"},{"key":"e_1_2_8_13_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-313X.2010.04247.x"},{"key":"e_1_2_8_14_1","doi-asserted-by":"publisher","DOI":"10.1104\/pp.18.01135"},{"key":"e_1_2_8_15_1","doi-asserted-by":"publisher","DOI":"10.1105\/tpc.107.057281"},{"key":"e_1_2_8_16_1","doi-asserted-by":"publisher","DOI":"10.1146\/annurev-arplant-112619-025827"},{"key":"e_1_2_8_17_1","doi-asserted-by":"crossref","first-page":"93","DOI":"10.1007\/s00425-020-03500-4","article-title":"AtKPNB1, an Arabidopsis Importin\u2010\u03b2 Protein, is Downstream of the RING E3 Ubiquitin Ligase AtAIRP1 in the ABA\u2010Mediated Drought Stress Response","volume":"252","author":"Oh T. 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