{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,27]],"date-time":"2026-09-27T10:29:13Z","timestamp":1790504953696,"version":"4.1.0"},"reference-count":18,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2018,9,3]],"date-time":"2018-09-03T00:00:00Z","timestamp":1535932800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Pigment Cell Melanoma Res"],"published-print":{"date-parts":[[2019,3]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Since localized treatment for vitiligo is as essential as systemic treatment, a reliable instrument for target evaluation is needed besides those for whole body evaluation. We developed the Vitiligo Extent Score for a Target Area (<jats:styled-content style=\"fixed-case\">VESTA<\/jats:styled-content>) using reference images of both marginal and perifollicular repigmentation to measure the repigmentation rate (%) in a target lesion. In the validation study, a total of 65 dermatologists in 10 institutes evaluated 17 pairs of vitiligo images (pre\u2010 and post\u2010treatment) using both a rough estimate and the <jats:styled-content style=\"fixed-case\">VESTA<\/jats:styled-content>. The <jats:styled-content style=\"fixed-case\">VESTA<\/jats:styled-content> (concordance correlation coefficient: 0.949, 95% confidence interval [<jats:styled-content style=\"fixed-case\">CI<\/jats:styled-content>] 0.942\u20130.955) was significantly more accurate than the rough estimate (0.896, 95% <jats:styled-content style=\"fixed-case\">CI<\/jats:styled-content>: 0.883\u20130.908). It was also associated with better inter\u2010rater reliability over the rough estimate, albeit not significant. The <jats:styled-content style=\"fixed-case\">VESTA<\/jats:styled-content> can afford intuitive, convenient, and reliable assessment of the treatment response in a target area, and would be useful in clinical practice as well as retrospective studies.<\/jats:p>","DOI":"10.1111\/pcmr.12730","type":"journal-article","created":{"date-parts":[[2018,8,17]],"date-time":"2018-08-17T07:57:33Z","timestamp":1534492653000},"page":"315-319","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":20,"title":["Development and validation of the Vitiligo Extent Score for a Target Area (<scp>VESTA<\/scp>) to assess the treatment response of a target lesion"],"prefix":"10.1111","volume":"32","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-5975-8519","authenticated-orcid":false,"given":"Jung Min","family":"Bae","sequence":"first","affiliation":[{"name":"Department of Dermatology College of Medicine The Catholic University of Korea  Seoul Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4477-1400","authenticated-orcid":false,"given":"Sang Ho","family":"Oh","sequence":"additional","affiliation":[{"name":"Department of Dermatology Yonsei University College of Medicine  Seoul Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8697-4292","authenticated-orcid":false,"given":"Hee Young","family":"Kang","sequence":"additional","affiliation":[{"name":"Department of Dermatology Ajou University Hospital School of Medicine  Suwon Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Young Wook","family":"Ryoo","sequence":"additional","affiliation":[{"name":"Department of Dermatology School of Medicine Keimyung University  Daegu Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Cheng\u2010Che E.","family":"Lan","sequence":"additional","affiliation":[{"name":"Department of Dermatology Kaohsiung Medical University Hospital, and College of Medicine Kaohsiung Medical University  Kaohsiung Taiwan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lei\u2010Hong","family":"Xiang","sequence":"additional","affiliation":[{"name":"Department of Dermatology Huashan Hospital Fudan University  Shanghai China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ki\u2010Ho","family":"Kim","sequence":"additional","affiliation":[{"name":"Department of Dermatology Dong\u2010A University School of Medicine  Busan Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tamio","family":"Suzuki","sequence":"additional","affiliation":[{"name":"Department of Dermatology Faculty of Medicine Yamagata University  Yamagata Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ichiro","family":"Katayama","sequence":"additional","affiliation":[{"name":"Department of Pigmentation Research and Therapeutics Graduate School of Medicine Osaka City University Osaka Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Seung\u2010Chul","family":"Lee","sequence":"additional","affiliation":[{"name":"Department of Dermatology Chonnam National University School of Medicine  Gwangju Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"name":"the East Asia Vitiligo Association","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2018,9,3]]},"reference":[{"issue":"1","key":"e_1_2_9_2_1","first-page":"30","article-title":"A practical method for the estimation of vitiligo surface area: A comparison between the point counting and digital planimetry techniques","volume":"17","author":"Aydin F.","year":"2007","journal-title":"European Journal of 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