{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,15]],"date-time":"2026-09-15T13:40:32Z","timestamp":1789479632297,"version":"build-2803163510"},"reference-count":21,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2022,10,1]],"date-time":"2022-10-01T00:00:00Z","timestamp":1664582400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Pigment Cell Melanoma Res"],"published-print":{"date-parts":[[2023,1]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Prospective data on correlation between dermoscopic features of vitiligo and disease activity are scarce. This study was conducted to sequentially determine the dermoscopic features of vitiligo and to evaluate their association with disease activity. A cohort of 30 patients with 60 active vitiligo patches on medical therapy was subjected to sequential clinical and dermoscopic examination at four weekly intervals till 16\u2009weeks. Disease activity at each visit was assessed using serial clinical photographs and modified vitiligo activity severity index. The dermoscopic images were merged and analysed for a predefined set of dermoscopic parameters by two blinded dermatologists. Paired analysis of dermoscopic features was done between baseline, and stabilized vitiligo patches at 12 and 16\u2009weeks. Pigment network changes (absent and reduced pigment network,<jats:italic>p<\/jats:italic>\u2009&lt;\u2009.001), perifollicular depigmentation (<jats:italic>p<\/jats:italic>\u00a0=\u00a0.02), ill\u2010defined margins (<jats:italic>p<\/jats:italic>\u00a0=\u00a0.04) and satellite lesions and micro\u2010Koebner phenomenon (<jats:italic>p<\/jats:italic>\u2009&lt;\u2009.001) were associated with active vitiligo while perifollicular repigmentation (<jats:italic>p<\/jats:italic>\u2009&lt;\u2009.001) was associated with stabilizing and repigmenting vitiligo. Satellite lesions and micro\u2010Koebner's phenomena were suggestive of unstable disease irrespective of site of target lesion, while perifollicular repigmentation was suggestive of stabilized\/repigmenting disease only at non\u2010acral sites. We found sequential dermoscopy to be useful to assess disease activity and potential for repigmentation in localized vitiligo.<\/jats:p>","DOI":"10.1111\/pcmr.13069","type":"journal-article","created":{"date-parts":[[2022,9,16]],"date-time":"2022-09-16T14:25:11Z","timestamp":1663338311000},"page":"33-41","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":17,"title":["A prospective observational study to sequentially determine the dermoscopic features of vitiligo and its association with disease activity in patients on medical treatment"],"prefix":"10.1111","volume":"36","author":[{"given":"Priyansh","family":"Gupta","sequence":"first","affiliation":[{"name":"Department of Dermatology, Venereology and Leprology Post Graduate Institute of Medical Education and Research Chandigarh India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6323-4988","authenticated-orcid":false,"given":"Keshavamurthy","family":"Vinay","sequence":"additional","affiliation":[{"name":"Department of Dermatology, Venereology and Leprology Post Graduate Institute of Medical Education and Research Chandigarh India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anuradha","family":"Bishnoi","sequence":"additional","affiliation":[{"name":"Department of Dermatology, Venereology and Leprology Post Graduate Institute of Medical Education and Research Chandigarh India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Muthu\u00a0Sendhil","family":"Kumaran","sequence":"additional","affiliation":[{"name":"Department of Dermatology, Venereology and Leprology Post Graduate Institute of Medical Education and Research Chandigarh India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Davinder","family":"Parsad","sequence":"additional","affiliation":[{"name":"Department of Dermatology, Venereology and Leprology Post Graduate Institute of Medical Education and Research Chandigarh India"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2022,10]]},"reference":[{"key":"e_1_2_12_2_1","doi-asserted-by":"publisher","DOI":"10.1007\/s40264-015-0287-7"},{"key":"e_1_2_12_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaad.2016.12.040"},{"key":"e_1_2_12_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.compmedimag.2004.03.001"},{"key":"e_1_2_12_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaad.2017.11.034"},{"key":"e_1_2_12_6_1","doi-asserted-by":"publisher","DOI":"10.1111\/dth.15099"},{"key":"e_1_2_12_7_1","doi-asserted-by":"publisher","DOI":"10.4103\/2349-5847.135430"},{"key":"e_1_2_12_8_1","doi-asserted-by":"publisher","DOI":"10.1007\/s13555-020-00431-6"},{"key":"e_1_2_12_9_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1468-3083.2011.04215.x"},{"key":"e_1_2_12_10_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00403-020-02068-z"},{"key":"e_1_2_12_11_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaad.2017.12.009"},{"key":"e_1_2_12_12_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaad.2010.02.010"},{"key":"e_1_2_12_13_1","doi-asserted-by":"publisher","DOI":"10.1111\/ijd.13795"},{"issue":"1","key":"e_1_2_12_14_1","doi-asserted-by":"crossref","first-page":"36","DOI":"10.4103\/JCAS.JCAS_75_18","article-title":"Cross\u2010sectional study of dermatoscopic findings in relation to activity in vitiligo: BPLeFoSK criteria for stability","volume":"12","author":"Nirmal B.","year":"2019","journal-title":"Journal of Cutaneous and Aesthetic Surgery"},{"key":"e_1_2_12_15_1","doi-asserted-by":"publisher","DOI":"10.1186\/1477-7525-1-58"},{"issue":"12","key":"e_1_2_12_16_1","first-page":"810","article-title":"Application of polarized light dermoscopy in the early diagnosis of vitiligo and its differential diagnosis from other depigmented diseases","volume":"42","author":"RuSong M.","year":"2009","journal-title":"Chinese Journal of Dermatology"},{"key":"e_1_2_12_17_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2133.2012.11197.x"},{"key":"e_1_2_12_18_1","doi-asserted-by":"publisher","DOI":"10.4103\/0378-6323.144144"},{"key":"e_1_2_12_19_1","doi-asserted-by":"publisher","DOI":"10.1111\/jdv.15604"},{"key":"e_1_2_12_20_1","doi-asserted-by":"publisher","DOI":"10.4103\/idoj.IDOJ_561_20"},{"issue":"4","key":"e_1_2_12_21_1","first-page":"3981","article-title":"Utility of dermoscopy for evaluating the therapeutic efficacy of tacrolimus ointment plus 308\u2010nm excimer laser combination therapy in localized vitiligo patients","volume":"15","author":"Wang L. 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