{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,8]],"date-time":"2026-09-08T13:21:47Z","timestamp":1788873707448,"version":"build-2803163510"},"reference-count":32,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2024,10,23]],"date-time":"2024-10-23T00:00:00Z","timestamp":1729641600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Pigment Cell Melanoma Res"],"published-print":{"date-parts":[[2025,1]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:p>\n                    Vitiligo is a chronic autoimmune disease, and current treatments for vitiligo have limited efficacy. Janus kinase (JAK) inhibitors could offer new therapeutic options. To evaluate the efficacy and safety of baricitinib, an oral JAK1\/2 inhibitor, combined with narrow\u2010band ultraviolet B (NB\u2010UVB) in vitiligo treatment. This prospective, controlled, open\u2010label study included adults with progressive non\u2010segmental vitiligo (NSV). Patients were assigned to combination therapy with baricitinib 2\u2009mg daily and NB\u2010UVB three times a week or NB\u2010UVB alone three times a week (control). The primary endpoint was the proportion of patients achieving 50% or greater improvement from baseline in the total Vitiligo Area Scoring Index (T\u2010VASI50) at week 16. Of the 33 patients (mean age, 34.1\u2009years; 27.3% women) who completed the study, 12 of 17 (70.6%) patients in the combination group and 2 of 16 (12.5%) in the control group had a T\u2010VASI50 response at week 16 (relative risk [RR]\u2009=\u20095.6; 95% CI\u2009=\u20091.5\u201321.4;\n                    <jats:italic>p<\/jats:italic>\n                    \u2009=\u20090.001). Adverse events were minor, including erythema, mild blister after phototherapy and acne. Combination therapy with low\u2010dose baricitinib and NB\u2010UVB was effective and well tolerated in adults with progressive NSV.\n                  <\/jats:p>","DOI":"10.1111\/pcmr.13209","type":"journal-article","created":{"date-parts":[[2024,10,23]],"date-time":"2024-10-23T10:07:10Z","timestamp":1729678030000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":20,"title":["Low\u2010Dose Baricitinib Plus Narrow\u2010Band Ultraviolet B for the Treatment of Progressive Non\u2010Segmental Vitiligo: A\u00a0Prospective, Controlled, Open\u2010Label Study"],"prefix":"10.1111","volume":"38","author":[{"given":"Zhonghui","family":"Hu","sequence":"first","affiliation":[{"name":"Department of Dermatology, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, State Key Laboratory of Complex Severe and Rare Diseases National Clinical Research Center for Dermatologic and Immunologic Diseases  Beijing China"},{"name":"Laboratory of Basic Medical Sciences; Department of Dermatology Qilu Hospital of Shandong University  Jinan China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lu","family":"Lu","sequence":"additional","affiliation":[{"name":"Department of Dermatology, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, State Key Laboratory of Complex Severe and Rare Diseases National Clinical Research Center for Dermatologic and Immunologic Diseases  Beijing China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jindi","family":"Feng","sequence":"additional","affiliation":[{"name":"Department of Dermatology, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, State Key Laboratory of Complex Severe and Rare Diseases National Clinical Research Center for Dermatologic and Immunologic Diseases  Beijing China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hongbin","family":"Song","sequence":"additional","affiliation":[{"name":"Department of Dermatology, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, State Key Laboratory of Complex Severe and Rare Diseases National Clinical Research Center for Dermatologic and Immunologic Diseases  Beijing China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shiyu","family":"Zhang","sequence":"additional","affiliation":[{"name":"Department of Dermatology, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, State Key Laboratory of Complex Severe and Rare Diseases National Clinical Research Center for Dermatologic and Immunologic Diseases  Beijing China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lu","family":"Yang","sequence":"additional","affiliation":[{"name":"Department of Dermatology, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, State Key Laboratory of Complex Severe and Rare Diseases National Clinical Research Center for Dermatologic and Immunologic Diseases  Beijing China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yuehua","family":"Liu","sequence":"additional","affiliation":[{"name":"Department of Dermatology, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, State Key Laboratory of Complex Severe and Rare Diseases National Clinical Research Center for Dermatologic and Immunologic Diseases  Beijing China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9998-2862","authenticated-orcid":false,"given":"Tao","family":"Wang","sequence":"additional","affiliation":[{"name":"Department of Dermatology, Peking Union Medical College Hospital, Chinese Academy of Medical 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