{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,7,30]],"date-time":"2025-07-30T12:31:55Z","timestamp":1753878715785,"version":"3.41.2"},"reference-count":7,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2025,4,11]],"date-time":"2025-04-11T00:00:00Z","timestamp":1744329600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Pigment Cell Melanoma Res"],"published-print":{"date-parts":[[2025,5]]},"abstract":"<jats:title>ABSTRACT<\/jats:title><jats:p>Acral melanoma (AM) is localized to the hands and feet including the palms, soles, fingers, toes, and nails, and is associated with a high degree of morbidity and mortality. It has a greater proportional incidence in non\u2010White patients and is often diagnosed at later stages than other cutaneous melanomas. Our study aimed to analyze demographic and clinical features associated with AM to better inform screening and early detection. Demographic and clinical data of patients with histopathologically confirmed AM seen at Weill Cornell Medicine were collected (6\/1\/2005\u20137\/20\/2022). ANOVA and <jats:italic>t<\/jats:italic>\u2010tests assessed differences in time\u2010to\u2010treatment and Breslow depth by demographics\/characteristics. Ninety\u2010five AMs were analyzed from 88 distinct patients, with a mean age of 62.48\u2009years (range: 18\u201398), 63.6% females, and 62.5% non\u2010Whites. Time\u2010to\u2010treatment was longer for White versus non\u2010White patients (41.8 vs. 29.1\u2009days, <jats:italic>p<\/jats:italic>\u2009=\u20090.0007), with a similar Breslow depth (White 1.29\u2009mm vs. non\u2010White 0.94\u2009mm, <jats:italic>p<\/jats:italic>\u2009=\u20090.26). On average, single\/widowed versus married patients had greater Breslow depth (1.53\u2009mm vs. 1.00\u2009mm, <jats:italic>p<\/jats:italic>\u2009=\u20090.0041), as did patients &gt;\u200965 versus \u2264\u200965\u2009years (1.26\u2009mm vs. 0.93\u2009mm, <jats:italic>p<\/jats:italic>\u2009=\u20090.0022). Since we found that AM is more common in non\u2010White versus White patients, we recommend increased education and screening among non\u2010White individuals. Also, since single\/widowed patients had greater Breslow depth than married patients, marriage may play a protective role in earlier cancer diagnosis, and enhanced melanoma education and screening, particularly targeting single individuals, could benefit patient outcomes.<\/jats:p>","DOI":"10.1111\/pcmr.70019","type":"journal-article","created":{"date-parts":[[2025,4,11]],"date-time":"2025-04-11T12:24:46Z","timestamp":1744374286000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Melanoma and Matrimony: Retrospective Study of Demographics, Marital Status, and Clinical Features of Patients With Acral Melanoma at a Single Academic Center"],"prefix":"10.1111","volume":"38","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-6713-7157","authenticated-orcid":false,"given":"Samantha Jo","family":"Albucker","sequence":"first","affiliation":[{"name":"Department of Medicine Stony Brook Southampton Hospital  Southampton New York USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Amar D.","family":"Desai","sequence":"additional","affiliation":[{"name":"Department of Medicine and Dermatology Northwestern Medicine  Chicago Illinois USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Julianne M.","family":"Falotico","sequence":"additional","affiliation":[{"name":"Department of Dermatology Stony Brook Hospital  Stony Brook New York USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Cynthia","family":"Magro","sequence":"additional","affiliation":[{"name":"Department of Pathology Weill Cornell Medicine  New York New York USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Silvia","family":"Mancebo","sequence":"additional","affiliation":[{"name":"Department of Dermatology Skagit Regional Health  Mount Vernon Washington USA"},{"name":"Department of Dermatology Weill Cornell Medicine  New York New York USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shari R.","family":"Lipner","sequence":"additional","affiliation":[{"name":"Department of Dermatology Weill Cornell Medicine  New York New York USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2025,4,11]]},"reference":[{"key":"e_1_2_2_9_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ad.2021.08.006"},{"key":"e_1_2_2_9_3_1","doi-asserted-by":"publisher","DOI":"10.1001\/jamanetworkopen.2021.11813"},{"key":"e_1_2_2_9_4_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMc1706162"},{"volume-title":"StatPearls","year":"2023","author":"Hall K. H.","key":"e_1_2_2_9_5_1"},{"key":"e_1_2_2_9_6_1","doi-asserted-by":"publisher","DOI":"10.1001\/jamadermatol.2013.5853"},{"key":"e_1_2_2_9_7_1","doi-asserted-by":"publisher","DOI":"10.1093\/gerona\/62.8.892"},{"key":"e_1_2_2_9_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaad.2021.07.049"}],"container-title":["Pigment Cell &amp; Melanoma Research"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/pcmr.70019","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,6,6]],"date-time":"2025-06-06T08:21:49Z","timestamp":1749198109000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/pcmr.70019"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,4,11]]},"references-count":7,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2025,5]]}},"alternative-id":["10.1111\/pcmr.70019"],"URL":"https:\/\/doi.org\/10.1111\/pcmr.70019","archive":["Portico"],"relation":{},"ISSN":["1755-1471","1755-148X"],"issn-type":[{"type":"print","value":"1755-1471"},{"type":"electronic","value":"1755-148X"}],"subject":[],"published":{"date-parts":[[2025,4,11]]},"assertion":[{"value":"2024-09-24","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-04-02","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-04-11","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"e70019"}}