{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,9,27]],"date-time":"2025-09-27T04:10:16Z","timestamp":1758946216659,"version":"3.44.0"},"reference-count":19,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2025,8,20]],"date-time":"2025-08-20T00:00:00Z","timestamp":1755648000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Pigment Cell Melanoma Res"],"published-print":{"date-parts":[[2025,9]]},"abstract":"<jats:title>ABSTRACT<\/jats:title><jats:p>There is a need to capture therapy\u2010related beliefs held by patients with conditions like vitiligo that have complex treatment regimens. Concerns about adverse effects and uncertainty about response to the prescribed treatment can impact adherence and the perceived treatment burden. This study aims to develop and validate a questionnaire on beliefs about therapy in patients with vitiligo. It is a cross\u2010sectional study. A vitiligo\u2010specific item pool was developed through literature review, in\u2010depth interviews with patients with vitiligo (<jats:italic>n<\/jats:italic>\u2009=\u200910), and expert surveys (<jats:italic>n<\/jats:italic>\u2009=\u20098). The instrument was studied on 140 patients for psychometric properties using the Vitiligo Treatment Impact score (VITs) and Medication Adherence Rating Scale\u20105 (MARS\u20105); self\u2010reported severity using PtGA (Patient Global Assessment) and Response VASI (Vitiligo Area Scoring Index). Exploratory factor analysis demonstrated a six\u2010factor structure with 21 items. Discriminant validity was evidenced by correlation between response VASI and questionnaire subscales (<jats:italic>r<\/jats:italic>\u2009=\u2009\u22120.538). Correlation with VITs (<jats:italic>r<\/jats:italic>\u2009=\u2009\u22120.610), MARS\u20105 (<jats:italic>r<\/jats:italic>\u2009=\u20090.453), and PtGA (<jats:italic>r<\/jats:italic>\u2009=\u20090.486) demonstrated construct and criterion validity, respectively. BTQ\u2010vitiligo demonstrated test\u2013retest reliability (<jats:italic>r<\/jats:italic>\u2009=\u20090.779) during the follow\u2010up visit. BTQ\u2010vitiligo is a validated instrument that helps clinicians understand patients' perspectives about therapy and tailor it accordingly to ensure adherence and further response to therapy. We developed and validated a BTQ\u2010vitiligo, a valuable tool for capturing therapy\u2010related beliefs in vitiligo, a complex dermatological disease with medication challenges. Although several patient\u2010reported outcome measures (PROMs) have been developed to assess various aspects of vitiligo, none exist to capture patients' beliefs about therapy, which is a key determinant of the perceived burden of treatment. Our questionnaire identifies general and specific medication beliefs across six domains, with 21 items included under it.<\/jats:p>","DOI":"10.1111\/pcmr.70049","type":"journal-article","created":{"date-parts":[[2025,8,20]],"date-time":"2025-08-20T19:33:46Z","timestamp":1755718426000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Development and Validation of Vitiligo\u2010Specific\u2010Belief About Therapy Questionnaire (<scp>BTQ<\/scp>\u2010Vitiligo)"],"prefix":"10.1111","volume":"38","author":[{"ORCID":"https:\/\/orcid.org\/0009-0006-8175-3988","authenticated-orcid":false,"given":"Sree Yazhini","family":"Ramar","sequence":"first","affiliation":[{"name":"Department of Dermatology and STD Jawaharlal Institute of Post Graduate Medical Education and Research  Puducherry India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9672-2029","authenticated-orcid":false,"given":"Sivaranjini","family":"Ramassamy","sequence":"additional","affiliation":[{"name":"Department of Dermatology and STD Jawaharlal Institute of Post Graduate Medical Education and Research  Puducherry India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5574-7943","authenticated-orcid":false,"given":"Malathi","family":"Munisamy","sequence":"additional","affiliation":[{"name":"Department of Dermatology and STD Jawaharlal Institute of Post Graduate Medical Education and Research  Puducherry India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Subitha","family":"Lakshminarayanan","sequence":"additional","affiliation":[{"name":"Department of Preventive &amp; Social Medicine Jawaharlal Institute of Post Graduate Medical Education and Research  Puducherry India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ruben","family":"Raj","sequence":"additional","affiliation":[{"name":"Department of Preventive &amp; Social Medicine Jawaharlal Institute of Post Graduate Medical Education and Research  Puducherry India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Raja Rajeswari","family":"Thanmalagan","sequence":"additional","affiliation":[{"name":"Department of Dermatology and STD Jawaharlal Institute of Post Graduate Medical Education and Research  Puducherry India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Remya","family":"Raj","sequence":"additional","affiliation":[{"name":"Department of Dermatology and STD Indira Gandhi Medical College &amp; Research Institute  Puducherry India"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2025,8,20]]},"reference":[{"key":"e_1_2_12_2_1","doi-asserted-by":"publisher","DOI":"10.1111\/bjd.21671"},{"key":"e_1_2_12_3_1","doi-asserted-by":"publisher","DOI":"10.1111\/bcp.14193"},{"key":"e_1_2_12_4_1","doi-asserted-by":"publisher","DOI":"10.1111\/jdv.18593"},{"key":"e_1_2_12_5_1","doi-asserted-by":"publisher","DOI":"10.1057\/s41270-020-00089-1"},{"key":"e_1_2_12_6_1","doi-asserted-by":"publisher","DOI":"10.1080\/08870440802071157"},{"key":"e_1_2_12_7_1","doi-asserted-by":"publisher","DOI":"10.1111\/bjd.13093"},{"key":"e_1_2_12_8_1","doi-asserted-by":"publisher","DOI":"10.1080\/08870449908407311"},{"issue":"9","key":"e_1_2_12_9_1","article-title":"Vitiligo: A Narrative Review","volume":"14","author":"Joge R. 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