{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,18]],"date-time":"2026-08-18T15:33:28Z","timestamp":1787067208671,"version":"build-2736575974"},"reference-count":67,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2026,1,21]],"date-time":"2026-01-21T00:00:00Z","timestamp":1768953600000},"content-version":"vor","delay-in-days":20,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2026,1,1]],"date-time":"2026-01-01T00:00:00Z","timestamp":1767225600000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Pigment Cell Melanoma Res"],"published-print":{"date-parts":[[2026,1]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:p>Excimer 308\u2010nm light is often used for vitiligo treatment in combination with adjuvants. We aimed to evaluate the efficacy of these combination therapies. We searched MEDLINE, Embase and the Cochrane Library from inception to November 2024. All randomised trials reporting efficacy outcomes for vitiligo patients treated with excimer 308\u2010nm light were included. Primary outcomes were achieving \u2265\u200950%, \u2265\u200975% and 100% skin repigmentation. Pairwise comparisons of treatment repigmentation were summarised as risk ratios (RRs) with 95% confidence intervals (CIs) and a frequentist, random\u2010effects network meta\u2010analysis with a graph\u2010theoretical approach was used to generate summary estimates. Thirty\u2010eight studies involving 1841 participants were included. Excimer 308\u2010nm light with topical calcineurin inhibitors or topical corticosteroids significantly improved repigmentation outcomes compared to excimer monotherapy with \u2265\u200950% (RR 1.47, 95% CI 1.19\u20131.81; RR 1.65, 95% CI 1.32\u20132.06) and \u2265\u2009100% repigmentation (RR 1.60, 95% CI 1.03\u20132.49; RR 2.31, 95% CI 1.50\u20133.56) respectively. Excimer in combination with topical antioxidants (RR 43.00, 95% CI 2.68\u2013688.68), intramuscular corticosteroid (RR 1.76, 95% CI 1.13\u20132.74) and platelet rich plasma (RR 1.76, 95% CI 1.32\u20132.35) enhanced \u2265\u200950% repigmentation. These findings highlight the value of combination therapy with excimer light as a useful option in the management of vitiligo.<\/jats:p>","DOI":"10.1111\/pcmr.70065","type":"journal-article","created":{"date-parts":[[2026,1,21]],"date-time":"2026-01-21T18:35:12Z","timestamp":1769020512000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["Excimer 308\u2010Nm Light in the Combination Treatment of Vitiligo: A Systematic Review and Network Meta\u2010Analysis"],"prefix":"10.1111","volume":"39","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-6114-8629","authenticated-orcid":false,"given":"Zhengyang","family":"Liu","sequence":"first","affiliation":[{"name":"Department of Dermatology Royal Melbourne Hospital  Parkville Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0847-6962","authenticated-orcid":false,"given":"Wey Han","family":"Ng","sequence":"additional","affiliation":[{"name":"Faculty of Medicine, Nursing and Health Sciences Monash University  Clayton Australia"},{"name":"Eastern Health  Melbourne Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4186-7391","authenticated-orcid":false,"given":"Samuel","family":"Morriss","sequence":"additional","affiliation":[{"name":"Department of Dermatology Royal Melbourne Hospital  Parkville Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9848-1919","authenticated-orcid":false,"given":"Zhao Feng","family":"Liu","sequence":"additional","affiliation":[{"name":"Faculty of Medicine, Nursing and Health Sciences Monash University  Clayton Australia"},{"name":"Skin Health Institute  Melbourne 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