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Leveraging the well\u2010established research framework provided by\n                    <jats:italic>Xiphophorus<\/jats:italic>\n                    , we have identified a spontaneously occurring albinism phenotype in swordtail fish\n                    <jats:styled-content style=\"fixed-case\">\n                      <jats:italic>Xiphophorus hellerii<\/jats:italic>\n                    <\/jats:styled-content>\n                    . Genetic mapping of albino fish showed that albinism is associated with a recessive mutation in the\n                    <jats:italic>oca2<\/jats:italic>\n                    gene. This discovery provides a novel opportunity to explore functions of the\n                    <jats:italic>oca2<\/jats:italic>\n                    gene in pigment cell differentiation, pigment synthesis, melanosome assembly and transportation function, and amelanotic melanoma development.\n                  <\/jats:p>","DOI":"10.1111\/pcmr.70113","type":"journal-article","created":{"date-parts":[[2026,7,23]],"date-time":"2026-07-23T06:44:02Z","timestamp":1784789042000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["A Recessive\n                    <i>oca2<\/i>\n                    Mutation Underlies Albinism in\n                    <i>Xiphophorus<\/i>\n                    Fish"],"prefix":"10.1111","volume":"39","author":[{"ORCID":"https:\/\/orcid.org\/0009-0003-5997-0001","authenticated-orcid":false,"given":"Yanting","family":"Xing","sequence":"first","affiliation":[{"name":"Institute for Molecular Life Sciences, Texas State University  San Marcos Texas USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"William","family":"Boswell","sequence":"additional","affiliation":[{"name":"Institute for Molecular Life Sciences, Texas State University  San Marcos Texas USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jessica","family":"Parker","sequence":"additional","affiliation":[{"name":"Institute for Molecular Life Sciences, Texas State University  San Marcos Texas USA"},{"name":"Department of Chemistry and Biochemistry Texas State University  San Marcos Texas USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1497-8945","authenticated-orcid":false,"given":"Kang","family":"Du","sequence":"additional","affiliation":[{"name":"Institute for Molecular Life Sciences, Texas State University  San Marcos Texas 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USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,7,22]]},"reference":[{"key":"e_1_2_10_2_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41586-024-07487-w"},{"key":"e_1_2_10_3_1","doi-asserted-by":"publisher","DOI":"10.1186\/1471-5945-12-9"},{"key":"e_1_2_10_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.preteyeres.2022.101091"},{"key":"e_1_2_10_5_1","doi-asserted-by":"publisher","DOI":"10.1111\/pcmr.12205"},{"key":"e_1_2_10_6_1","doi-asserted-by":"publisher","DOI":"10.7554\/eLife.04543"},{"key":"e_1_2_10_7_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0080823"},{"key":"e_1_2_10_8_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0749.2005.00227.x"},{"key":"e_1_2_10_9_1","doi-asserted-by":"publisher","DOI":"10.1034\/j.1600-0749.2001.140203.x"},{"key":"e_1_2_10_10_1","doi-asserted-by":"publisher","DOI":"10.1186\/1471-2156-13-62"},{"key":"e_1_2_10_11_1","doi-asserted-by":"publisher","DOI":"10.1038\/jid.2009.258"},{"key":"e_1_2_10_12_1","doi-asserted-by":"publisher","DOI":"10.1111\/pcmr.12982"},{"key":"e_1_2_10_13_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0625.2009.00846.x"},{"key":"e_1_2_10_14_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12863-017-0504-8"},{"key":"e_1_2_10_15_1","doi-asserted-by":"publisher","DOI":"10.1186\/1750-1172-2-43"},{"key":"e_1_2_10_16_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jdermsci.2012.09.016"},{"key":"e_1_2_10_17_1","doi-asserted-by":"publisher","DOI":"10.1002\/jez.10051"},{"key":"e_1_2_10_18_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0625.2010.01115.x"},{"key":"e_1_2_10_19_1","doi-asserted-by":"publisher","DOI":"10.1038\/sj.ejhg.5201415"},{"key":"e_1_2_10_20_1","doi-asserted-by":"publisher","DOI":"10.1155\/2014\/905472"},{"key":"e_1_2_10_21_1","doi-asserted-by":"publisher","DOI":"10.1186\/gb-2013-14-4-r36"},{"key":"e_1_2_10_22_1","doi-asserted-by":"publisher","DOI":"10.1111\/pcmr.12799"},{"key":"e_1_2_10_23_1","doi-asserted-by":"publisher","DOI":"10.1038\/nmeth.1923"},{"key":"e_1_2_10_24_1","doi-asserted-by":"publisher","DOI":"10.1093\/bioinformatics\/btr509"},{"key":"e_1_2_10_25_1","doi-asserted-by":"publisher","DOI":"10.1093\/bioinformatics\/btp324"},{"key":"e_1_2_10_26_1","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.2010133117"},{"key":"e_1_2_10_27_1","doi-asserted-by":"publisher","DOI":"10.1042\/BSR20230060"},{"key":"e_1_2_10_28_1","doi-asserted-by":"publisher","DOI":"10.1016\/1357-4310(96)81798-9"},{"key":"e_1_2_10_29_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cub.2021.06.077"},{"key":"e_1_2_10_30_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11010-015-2337-y"},{"key":"e_1_2_10_31_1","doi-asserted-by":"publisher","DOI":"10.1126\/science.aba5216"},{"key":"e_1_2_10_32_1","doi-asserted-by":"publisher","DOI":"10.1038\/ng1700"},{"key":"e_1_2_10_33_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0238529"},{"key":"e_1_2_10_34_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.gene.2013.11.102"},{"key":"e_1_2_10_35_1","doi-asserted-by":"publisher","DOI":"10.1038\/361072a0"},{"key":"e_1_2_10_36_1","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.91.25.12071"},{"key":"e_1_2_10_37_1","doi-asserted-by":"publisher","DOI":"10.1111\/pcmr.12409"},{"key":"e_1_2_10_38_1","doi-asserted-by":"publisher","DOI":"10.1242\/dmm.050382"},{"key":"e_1_2_10_39_1","doi-asserted-by":"publisher","DOI":"10.1111\/pcmr.13196"},{"key":"e_1_2_10_40_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.bbamem.2020.183318"},{"key":"e_1_2_10_41_1","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.0511248103"},{"key":"e_1_2_10_42_1","article-title":"Nonhuman 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