{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,23]],"date-time":"2026-09-23T15:39:46Z","timestamp":1790177986491,"version":"4.1.0"},"reference-count":27,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2013,5,20]],"date-time":"2013-05-20T00:00:00Z","timestamp":1369008000000},"content-version":"vor","delay-in-days":19,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Psychiatry Clin Neurosci"],"published-print":{"date-parts":[[2013,5]]},"abstract":"Aims<\/jats:title>The purpose of this study was to examine the usefulness of near\u2010infrared spectroscopy (NIRS<\/jats:styled-content>) for identifying abnormalities in prefrontal brain activity in children with autism spectrum disorders (ASD<\/jats:styled-content>) as they inferred the mental states of others.<\/jats:p><\/jats:sec>Methods<\/jats:title>The subjects were 16 children with ASD<\/jats:styled-content> aged between 8 and 14 years and 16 age\u2010matched healthy control children. Oxygenated hemoglobin concentration was measured in the subject's prefrontal brain region on NIRS<\/jats:styled-content> during tasks expressing a person's mental state (MS<\/jats:styled-content> task) and expressing an object's characteristics (OC<\/jats:styled-content> task).<\/jats:p><\/jats:sec>Results<\/jats:title>There was a significant main effect of group (ASD<\/jats:styled-content> vs control), with the control group having more activity than the ASD<\/jats:styled-content> group. But there was no significant main effect of task (MS<\/jats:styled-content> task vs OC<\/jats:styled-content> task) or hemisphere (right vs left). Significant interactions of task and group were found, with the control group showing more activity than the ASD<\/jats:styled-content> group during the MS<\/jats:styled-content> task relative to the OC<\/jats:styled-content> task.<\/jats:p><\/jats:sec>Conclusions<\/jats:title>NIRS<\/jats:styled-content> showed that there was lower activity in the prefrontal brain area when children with ASD<\/jats:styled-content> performed MS<\/jats:styled-content> tasks. Therefore, clinicians might be able to use NIRS<\/jats:styled-content> and these tasks for conveniently detecting brain dysfunction in children with ASD<\/jats:styled-content> related to inferring mental states, in the clinical setting.<\/jats:p><\/jats:sec>","DOI":"10.1111\/pcn.12052","type":"journal-article","created":{"date-parts":[[2013,5,20]],"date-time":"2013-05-20T07:33:50Z","timestamp":1369035230000},"page":"203-209","source":"Crossref","is-referenced-by-count":26,"title":["Usefulness of near\u2010infrared spectroscopy to detect brain dysfunction in children with autism spectrum disorder when inferring the mental state of others"],"prefix":"10.1111","volume":"67","author":[{"given":"Ryoichiro","family":"Iwanaga","sequence":"first","affiliation":[{"name":"Division of Physical and Occupational Therapy Department of Health Sciences Nagasaki University Graduate School of Biomedical Sciences Nagasaki Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Goro","family":"Tanaka","sequence":"additional","affiliation":[{"name":"Division of Physical and Occupational Therapy Department of Health Sciences Nagasaki University Graduate School of Biomedical Sciences Nagasaki Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hideyuki","family":"Nakane","sequence":"additional","affiliation":[{"name":"Division of Physical and Occupational Therapy Department of Health Sciences Nagasaki University Graduate School of Biomedical Sciences Nagasaki Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sumihisa","family":"Honda","sequence":"additional","affiliation":[{"name":"Division of Physical and Occupational Therapy Department of Health Sciences Nagasaki University Graduate School of Biomedical Sciences Nagasaki Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Akira","family":"Imamura","sequence":"additional","affiliation":[{"name":"Division of Neuropsychiatry Department of Translation Medical Sciences Nagasaki University Graduate School of Biomedical Sciences Nagasaki Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hiroki","family":"Ozawa","sequence":"additional","affiliation":[{"name":"Division of Neuropsychiatry Department of Translation Medical Sciences Nagasaki University Graduate School of Biomedical Sciences Nagasaki Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2013,5,20]]},"reference":[{"key":"e_1_2_6_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/0010-0277(85)90022-8"},{"key":"e_1_2_6_3_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1469-7610.1994.tb01159.x"},{"key":"e_1_2_6_4_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1469-7610.1997.tb01599.x"},{"key":"e_1_2_6_5_1","doi-asserted-by":"publisher","DOI":"10.1098\/rstb.2002.1218"},{"key":"e_1_2_6_6_1","doi-asserted-by":"publisher","DOI":"10.1006\/nimg.1999.0525"},{"key":"e_1_2_6_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0028-3932(99)00053-6"},{"key":"e_1_2_6_8_1","doi-asserted-by":"publisher","DOI":"10.1038\/nrn844"},{"key":"e_1_2_6_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.brainres.2010.07.057"},{"key":"e_1_2_6_10_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1749-818X.2008.00122.x"},{"key":"e_1_2_6_11_1","doi-asserted-by":"publisher","DOI":"10.1093\/brain\/awf189"},{"key":"e_1_2_6_12_1","doi-asserted-by":"publisher","DOI":"10.1080\/17470911003708032"},{"key":"e_1_2_6_13_1","doi-asserted-by":"publisher","DOI":"10.1111\/1469-7610.00165"},{"key":"e_1_2_6_14_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0887-8994(02)00432-0"},{"key":"e_1_2_6_15_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.bbr.2006.05.020"},{"key":"e_1_2_6_16_1","doi-asserted-by":"publisher","DOI":"10.1006\/nimg.1997.0270"},{"key":"e_1_2_6_17_1","doi-asserted-by":"publisher","DOI":"10.1016\/0304-3940(94)90679-3"},{"key":"e_1_2_6_18_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.braindev.2010.11.007"},{"key":"e_1_2_6_19_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.autneu.2010.03.011"},{"key":"e_1_2_6_20_1","doi-asserted-by":"publisher","DOI":"10.1176\/appi.books.9780890423349"},{"key":"e_1_2_6_21_1","volume-title":"Pervasive Developmental Disorders Autism Society Japan Rating Scale","author":"PARS committee","year":"2008"},{"key":"e_1_2_6_22_1","unstructured":"IiT HayashiE HiroseY TojoY.The high\u2010functioning autism spectrum screening questionnaire 2003 39\u201044. Grant\u2010in\u2010Aid for Scientific Research (KAKENHI) report No.13410042).National Institute of Special Needs Education Kanagawa 2002(in Japanese)."},{"key":"e_1_2_6_23_1","doi-asserted-by":"publisher","DOI":"10.1023\/A:1023040610384"},{"key":"e_1_2_6_24_1","volume-title":"Enpitsuga\u2010note kao (The Face)","author":"Shikaku\u2010design Institute","year":"1987"},{"key":"e_1_2_6_25_1","volume-title":"International Affective Picture System (IAPS): Affective Ratings of Pictures and Instruction Manual","author":"Lang PJ","year":"2008"},{"key":"e_1_2_6_26_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.neuroimage.2003.08.026"},{"key":"e_1_2_6_27_1","doi-asserted-by":"publisher","DOI":"10.1152\/jappl.2001.90.5.1657"},{"key":"e_1_2_6_28_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11065-010-9138-6"}],"container-title":["Psychiatry and Clinical Neurosciences"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fpcn.12052","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/pcn.12052","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,14]],"date-time":"2023-10-14T09:14:42Z","timestamp":1697274882000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/pcn.12052"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2013,5]]},"references-count":27,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2013,5]]}},"alternative-id":["10.1111\/pcn.12052"],"URL":"https:\/\/doi.org\/10.1111\/pcn.12052","archive":["Portico"],"relation":{},"ISSN":["1323-1316","1440-1819"],"issn-type":[{"value":"1323-1316","type":"print"},{"value":"1440-1819","type":"electronic"}],"subject":[],"published":{"date-parts":[[2013,5]]}}}