{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,9]],"date-time":"2025-10-09T21:01:54Z","timestamp":1760043714698},"reference-count":15,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2014,1,9]],"date-time":"2014-01-09T00:00:00Z","timestamp":1389225600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Psychiatry Clin Neurosci"],"published-print":{"date-parts":[[2014,5]]},"abstract":"Aim<\/jats:title>The aim of this study was to clarify the clinical features of designer\u2010drug\u2010abusing patients through comparisons with methamphetamine\u2010abusing patients and hypnotics\/anxiolytics\u2010abusing patients.<\/jats:p><\/jats:sec>Methods<\/jats:title>Information on 126 designer\u2010drug\u2010abusing patients, 138 methamphetamine\u2010abusing patients, and 87 hypnotics\/anxiolytics\u2010abusing patients was extracted from the 2012 database of \u2018The Nationwide Mental Hospital Survey on Drug\u2010related Psychiatric Disorders\u2019 and the clinical variables of designer\u2010drug\u2010abusing patients compared with those of the other two groups.<\/jats:p><\/jats:sec>Results<\/jats:title>Multivariate analysis indicated the following significant differences between designer\u2010drug\u2010abusing patients and the other two types of patients: designer\u2010drug\u2010abusing patients were younger, included more men, had higher education and fewer relationships with antisocial groups, and included more patients meeting ICD<\/jats:styled-content>\u201010 F1<\/jats:styled-content> sub\u2010classification categories of \u2018Harmful use\u2019 and \u2018Psychotic disorders\u2019 than methamphetamine\u2010abusing patients. Compared with hypnotics\/anxiolytics\u2010abusing patients, designer\u2010drug\u2010abusing patients were younger, included more men and more patients meeting criteria for \u2018Psychotic disorders\u2019, and more frequently cited \u2018peer pressure\u2019, \u2018unable to refuse\u2019, and \u2018seeking stimulation\u2019 as reasons for using the drug.<\/jats:p><\/jats:sec>Conclusion<\/jats:title>The advent of designer drugs has created a new class of drug abuse, and abuse of designer drugs may carry a strong psychosis\u2010inducing risk, exceeding that of methamphetamine.<\/jats:p><\/jats:sec>","DOI":"10.1111\/pcn.12140","type":"journal-article","created":{"date-parts":[[2014,1,10]],"date-time":"2014-01-10T02:48:29Z","timestamp":1389322109000},"page":"374-382","source":"Crossref","is-referenced-by-count":8,"title":["Clinical features of patients with designer\u2010drug\u2010related disorder in J<\/scp>apan: A comparison with patients with methamphetamine\u2010 and hypnotic\/anxiolytic\u2010related disorders"],"prefix":"10.1111","volume":"68","author":[{"given":"Toshihiko","family":"Matsumoto","sequence":"first","affiliation":[{"name":"Department of Drug Dependence Research National Institute of Mental Health National Center of Neurology and Psychiatry Tokyo Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hisateru","family":"Tachimori","sequence":"additional","affiliation":[{"name":"Department of Mental Health Administration National Institute of Mental Health National Center of Neurology and Psychiatry Tokyo Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yuko","family":"Tanibuchi","sequence":"additional","affiliation":[{"name":"Department of Psychiatry Chiba Hospital Chiba Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ayumi","family":"Takano","sequence":"additional","affiliation":[{"name":"Department of Drug Dependence Research National Institute of Mental Health National Center of Neurology and Psychiatry Tokyo Japan"},{"name":"Department of Psychiatric Nursing Graduate School of Medicine The University of Tokyo Tokyo Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kiyoshi","family":"Wada","sequence":"additional","affiliation":[{"name":"Department of Drug Dependence Research National Institute of Mental Health National Center of Neurology and Psychiatry Tokyo Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2014,1,9]]},"reference":[{"key":"e_1_2_6_2_1","unstructured":"MatsumotoT TanibuchiY TakanoA KobayashiO WadaK.A nationwide survey of drug\u2010related psychiatric illness in hospitals with psychiatric inpatient units.The Research Report of 2012 Health Labour Sciences Research Grant (Research on Regulatory Science of Pharmaceuticals and Medical Devices) from the Ministry of Health Labour and Welfare of Japan pp.111\u2013144 2013(in Japanese)."},{"key":"e_1_2_6_3_1","doi-asserted-by":"publisher","DOI":"10.1111\/dar.12055"},{"key":"e_1_2_6_4_1","doi-asserted-by":"publisher","DOI":"10.1177\/0960327111421945"},{"key":"e_1_2_6_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.annemergmed.2012.03.007"},{"key":"e_1_2_6_6_1","doi-asserted-by":"publisher","DOI":"10.3928\/02793695-20120703-04"},{"key":"e_1_2_6_7_1","doi-asserted-by":"publisher","DOI":"10.3109\/00952990.2011.643999"},{"key":"e_1_2_6_8_1","doi-asserted-by":"publisher","DOI":"10.1001\/jama.2012.34423"},{"key":"e_1_2_6_9_1","first-page":"323","article-title":"A research on the acute intoxication cases by the \u2018Gouhou Herb,\u2019 of which information were reported to the Japan Poison Information Center","volume":"24","author":"Kuroki Y","year":"2011","journal-title":"Jpn. 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