{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,20]],"date-time":"2026-09-20T11:17:14Z","timestamp":1789903034320,"version":"4.0.1"},"reference-count":22,"publisher":"Wiley","issue":"7","license":[{"start":{"date-parts":[[2014,4,13]],"date-time":"2014-04-13T00:00:00Z","timestamp":1397347200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Psychiatry Clin Neurosci"],"published-print":{"date-parts":[[2014,7]]},"abstract":"Aim<\/jats:title>In the present study, the P300<\/jats:styled-content> component of the emotion\u2010loaded visual event\u2010related potential in response to photographs of babies crying or smiling was measured to evaluate cognitive function in elderly subjects, including those with dementia.<\/jats:p><\/jats:sec>Methods<\/jats:title>The subjects were 48 elderly people who consulted a memory disorder clinic. The visual event\u2010related potential was measured using oddball tasks. Brain waves were recorded from four sites. We analyzed the P300<\/jats:styled-content> amplitude and latency. Subjects were divided into three groups (the dementia with A<\/jats:styled-content>lzheimer's disease group [ADG<\/jats:styled-content>]; the intermediate group [MG<\/jats:styled-content>], and the healthy group [HG<\/jats:styled-content>]) based on the Revised Hasegawa Dementia Scale, Mini\u2010mental State Examination scores and the Clinical Dementia Rating.<\/jats:p><\/jats:sec>Results<\/jats:title>For all subjects, there was a significant positive correlation between P300<\/jats:styled-content> latency and Z<\/jats:styled-content>\u2010score of voxel\u2010based specific regional analysis for Alzheimer's disease for crying or smiling faces. There was a negative correlation between P300<\/jats:styled-content> amplitude and Z<\/jats:styled-content>\u2010score for the crying face. MG<\/jats:styled-content> subjects were divided into two groups (high risk: HRMG<\/jats:styled-content>, low risk: LRMG<\/jats:styled-content>) based on Z<\/jats:styled-content>\u2010scores (HRMG<\/jats:styled-content>\u2009\u2265\u20092.0). The P300<\/jats:styled-content> amplitude of ADG<\/jats:styled-content> was significantly smaller than that of HG<\/jats:styled-content>, and the P300<\/jats:styled-content> latency of ADG<\/jats:styled-content> was significantly longer than those of other groups for crying or smiling faces. The P300<\/jats:styled-content> latency of HRMG<\/jats:styled-content> was significantly longer than that of LRMG<\/jats:styled-content> for the smiling face. Furthermore, the P300<\/jats:styled-content> latency for the crying face was significantly shorter than that for the smiling face in HG<\/jats:styled-content> and ADG<\/jats:styled-content>.<\/jats:p><\/jats:sec>Conclusion<\/jats:title>These findings suggest that analysis of P300<\/jats:styled-content> components of the emotion\u2010loaded visual event\u2010related potential may be a useful neuropsychological index for the diagnosis of A<\/jats:styled-content>lzheimer's disease and high\u2010risk subjects.<\/jats:p><\/jats:sec>","DOI":"10.1111\/pcn.12162","type":"journal-article","created":{"date-parts":[[2014,1,22]],"date-time":"2014-01-22T08:30:47Z","timestamp":1390379447000},"page":"558-567","source":"Crossref","is-referenced-by-count":24,"title":["Evaluation of P300<\/scp> components for emotion\u2010loaded visual event\u2010related potential in elderly subjects, including those with dementia"],"prefix":"10.1111","volume":"68","author":[{"given":"Yasue","family":"Asaumi","sequence":"first","affiliation":[{"name":"Cognitive and Molecular Research Institute of Brain Diseases Kurume University Fukuoka Japan"},{"name":"Kyushu University of Nursing and Social Welfare Kumamoto Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kiichiro","family":"Morita","sequence":"additional","affiliation":[{"name":"Cognitive and Molecular Research Institute of Brain Diseases Kurume University Fukuoka Japan"},{"name":"Department of Neuropsychiatry Kurume University School of Medicine Fukuoka Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Youko","family":"Nakashima","sequence":"additional","affiliation":[{"name":"Cognitive and Molecular Research Institute of Brain Diseases Kurume University Fukuoka Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Akemi","family":"Muraoka","sequence":"additional","affiliation":[{"name":"Cognitive and Molecular Research Institute of Brain Diseases Kurume University Fukuoka Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Naohisa","family":"Uchimura","sequence":"additional","affiliation":[{"name":"Cognitive and Molecular Research Institute of Brain Diseases Kurume University Fukuoka Japan"},{"name":"Department of Neuropsychiatry Kurume University School of Medicine Fukuoka Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2014,4,13]]},"reference":[{"key":"e_1_2_6_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/S1047-9651(03)00109-8"},{"key":"e_1_2_6_3_1","doi-asserted-by":"publisher","DOI":"10.1097\/00004691-199210000-00002"},{"key":"e_1_2_6_4_1","doi-asserted-by":"publisher","DOI":"10.1615\/CritRevNeurobiol.v14.i3-4.20"},{"key":"e_1_2_6_5_1","doi-asserted-by":"crossref","first-page":"201","DOI":"10.1080\/00029238.1991.11080373","volume":"31","author":"Polich J","year":"1991","journal-title":"Am. 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