{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,9]],"date-time":"2026-07-09T11:51:42Z","timestamp":1783597902808,"version":"3.55.0"},"reference-count":37,"publisher":"Wiley","issue":"12","license":[{"start":{"date-parts":[[2015,8,18]],"date-time":"2015-08-18T00:00:00Z","timestamp":1439856000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/100012553","name":"Chang Gung Memorial Hospital","doi-asserted-by":"crossref","award":["CMRPG 3B1181"],"award-info":[{"award-number":["CMRPG 3B1181"]}],"id":[{"id":"10.13039\/100012553","id-type":"DOI","asserted-by":"crossref"}]},{"DOI":"10.13039\/100012553","name":"Chang Gung Memorial Hospital","doi-asserted-by":"crossref","award":["CRRPG5C0173"],"award-info":[{"award-number":["CRRPG5C0173"]}],"id":[{"id":"10.13039\/100012553","id-type":"DOI","asserted-by":"crossref"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Psychiatry Clin Neurosci"],"published-print":{"date-parts":[[2015,12]]},"abstract":"<jats:sec><jats:title>Aims<\/jats:title><jats:p>Childhood obstructive sleep apnea syndrome (<jats:styled-content style=\"fixed-case\">OSA<\/jats:styled-content>) affects not only the children's physical health, but also their mental development, behavioral problems and learning difficulties. Therefore, an early diagnosis is important. However, the assessment tools of polysomnography are demanding. The Obstructive Sleep Apnea Questionnaire\u201018 (<jats:styled-content style=\"fixed-case\">OSA<\/jats:styled-content>\u201018) is designed to screen <jats:styled-content style=\"fixed-case\">OSA<\/jats:styled-content> and has good reliability and validity. The goal of this study was to validate the <jats:styled-content style=\"fixed-case\">C<\/jats:styled-content>hinese version of the <jats:styled-content style=\"fixed-case\">OSA<\/jats:styled-content>\u201018, to analyze the frequency of symptoms and find the most common symptoms of <jats:styled-content style=\"fixed-case\">OSA<\/jats:styled-content> in <jats:styled-content style=\"fixed-case\">T<\/jats:styled-content>aiwanese children.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>We validated the <jats:styled-content style=\"fixed-case\">OSA<\/jats:styled-content>\u201018 in an ethnic <jats:styled-content style=\"fixed-case\">C<\/jats:styled-content>hinese group and compared the treatment outcomes to show the sensitivity of the questionnaire. The caregivers completed the questionnaire twice at an interval of 4 weeks to test reliability. In the validation study, we included 88 <jats:styled-content style=\"fixed-case\">OSA<\/jats:styled-content> children. The <jats:styled-content style=\"fixed-case\">OSA<\/jats:styled-content>\u201018 and follow\u2010up polysomnography were performed before and 6 months after adenotonsillectomy.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Results showed the excellent test\u2013retest reliability (<jats:italic>r<\/jats:italic>\u2009=\u20090.84**) of the <jats:styled-content style=\"fixed-case\">OSA<\/jats:styled-content>\u201018. There was a statistically significant correlation between the <jats:styled-content style=\"fixed-case\">OSA<\/jats:styled-content>\u201018 and, respectively, the <jats:styled-content style=\"fixed-case\">A<\/jats:styled-content>pnea\u2013<jats:styled-content style=\"fixed-case\">H<\/jats:styled-content>ypopnea <jats:styled-content style=\"fixed-case\">I<\/jats:styled-content>ndex (<jats:italic>r<\/jats:italic>\u2009=\u20090.29*), and the <jats:styled-content style=\"fixed-case\">H<\/jats:styled-content>ypopnea <jats:styled-content style=\"fixed-case\">I<\/jats:styled-content>ndex (<jats:italic>r<\/jats:italic>\u2009=\u20090.29*). <jats:styled-content style=\"fixed-case\">Q<\/jats:styled-content>uality of life showed a significant correlation with the <jats:styled-content style=\"fixed-case\">A<\/jats:styled-content>pnea <jats:styled-content style=\"fixed-case\">I<\/jats:styled-content>ndex (<jats:italic>r<\/jats:italic>\u2009=\u20090.43**), central apnea count (<jats:italic>r<\/jats:italic>\u2009=\u20090.50***), and mixed apnea count (<jats:italic>r<\/jats:italic>\u2009=\u20090.36*). The cut\u2010off point of the <jats:styled-content style=\"fixed-case\">OSA<\/jats:styled-content>\u201018 total scores for detecting pediatric <jats:styled-content style=\"fixed-case\">OSA<\/jats:styled-content> in children aged 6\u201312 years was 66. The common symptoms of pediatric <jats:styled-content style=\"fixed-case\">OSA<\/jats:styled-content> were poor attention span, loud snoring, caregiver worried about child's health, difficulty awakening, and mouth breathing.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Our results show that the <jats:styled-content style=\"fixed-case\">C<\/jats:styled-content>hinese version of the <jats:styled-content style=\"fixed-case\">OSA<\/jats:styled-content>\u201018 is a reliable and valid instrument. The questionnaire also showed improvement in the quality of life of <jats:styled-content style=\"fixed-case\">OSA<\/jats:styled-content> children post\u2010adenotonsillectomy.<\/jats:p><\/jats:sec>","DOI":"10.1111\/pcn.12331","type":"journal-article","created":{"date-parts":[[2015,7,1]],"date-time":"2015-07-01T08:56:54Z","timestamp":1435741014000},"page":"752-762","source":"Crossref","is-referenced-by-count":34,"title":["Clinical manifestations of pediatric obstructive sleep apnea syndrome: Clinical utility of the <scp>C<\/scp>hinese\u2010version <scp>O<\/scp>bstructive <scp>S<\/scp>leep <scp>A<\/scp>pnea <scp>Q<\/scp>uestionaire\u201018"],"prefix":"10.1111","volume":"69","author":[{"given":"Yu\u2010Shu","family":"Huang","sequence":"first","affiliation":[{"name":"Department of Child Psychiatry and Sleep Center Chang Gung Memorial Hospital  Taoyuan Taiwan"},{"name":"College of Medicine Chang Gung University  Taoyuan Taiwan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fang\u2010Ming","family":"Hwang","sequence":"additional","affiliation":[{"name":"Department of Education National Chia\u2010Yi University  Chiayi Taiwan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Cheng\u2010Hui","family":"Lin","sequence":"additional","affiliation":[{"name":"Department of Cranio\u2010Facial Center and Sleep Center Chang Gung Memorial Hospital  Taoyuan Taiwan"},{"name":"College of Medicine Chang Gung University  Taoyuan Taiwan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Li\u2010Ang","family":"Lee","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology and Sleep Center Chang Gung Memorial Hospital  Taoyuan Taiwan"},{"name":"College of Medicine Chang Gung University  Taoyuan Taiwan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Po\u2010Yu","family":"Huang","sequence":"additional","affiliation":[{"name":"Computational Intelligence Technology Center Industrial Technology Research Institute  Hsinchu Taiwan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Szu\u2010Tzu","family":"Chiu","sequence":"additional","affiliation":[{"name":"Department of Athletic Training and Health National Taiwan Sport University  Taoyuan Taiwan"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2015,8,18]]},"reference":[{"key":"e_1_2_6_2_1","doi-asserted-by":"publisher","DOI":"10.1542\/peds.102.3.616"},{"key":"e_1_2_6_3_1","doi-asserted-by":"publisher","DOI":"10.1164\/rccm.2109080"},{"key":"e_1_2_6_4_1","first-page":"187","article-title":"Epidemiology of obstructive sleep apnea syndrome","volume":"95","author":"Ferini\u2010Strambi L","year":"2004","journal-title":"Minerva 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