{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,31]],"date-time":"2025-10-31T22:02:24Z","timestamp":1761948144333},"reference-count":30,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2016,4,5]],"date-time":"2016-04-05T00:00:00Z","timestamp":1459814400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Psychiatry Clin Neurosci"],"published-print":{"date-parts":[[2016,5]]},"abstract":"<jats:sec><jats:title>Aim<\/jats:title><jats:p>Atypical antipsychotic treatment (e.g. risperidone) has been found to improve social functioning more than standard antipsychotic treatment. However, it is unclear which specific social behaviors are implicated in this improvement. The current study employed an interactive puzzle game to examine how social behaviors contribute to the improvement of social functioning by comparing patients receiving risperidone with those receiving trifluoperazine.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Scores on the Positive and Negative Syndrome Scale, executive functioning, and social functioning were obtained from 24 patients with schizophrenia receiving either risperidone (<jats:italic>n<\/jats:italic> = 12) or trifluoperazine (<jats:italic>n<\/jats:italic> = 12), before their social behavior was measured in the interactive Tangrams Game. Immediately after the Tangrams Game, participants filled in two questionnaires measuring their interpersonal trust and rejection toward their game partner.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Patients receiving risperidone showed more social engagement, cooperative behavior and interpersonal trust toward their game partners than those receiving trifluoperazine. Additional multivariate analysis of variance revealed that lower affiliative behavior was a function of positive symptoms; interpersonal trust had an impact on social engagement but executive functioning did not explain lower interpersonal trust or social disengagement.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Improvement of social competence by risperidone might be related to the enhancement of both social behaviors and interpersonal trust as well as better symptom resolution.<\/jats:p><\/jats:sec>","DOI":"10.1111\/pcn.12382","type":"journal-article","created":{"date-parts":[[2016,2,11]],"date-time":"2016-02-11T12:06:25Z","timestamp":1455192385000},"page":"218-226","source":"Crossref","is-referenced-by-count":4,"title":["Different mechanisms of risperidone result in improved interpersonal trust, social engagement and cooperative behavior in patients with schizophrenia compared to trifluoperazine"],"prefix":"10.1111","volume":"70","author":[{"given":"Wai Shing","family":"Tse","sequence":"first","affiliation":[{"name":"Department of Educational Psychology Chinese University of Hong Kong  Hong Kong China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ann Siu Wah","family":"Wong","sequence":"additional","affiliation":[{"name":"Department of Applied Social Studies City University of Hong Kong  Hong Kong China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Fu","family":"Chan","sequence":"additional","affiliation":[{"name":"Department of Psychiatry North District Hospital  Hong Kong China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Alfred Hin Tat","family":"Pang","sequence":"additional","affiliation":[{"name":"Department of Psychiatry North District Hospital  Hong Kong China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Alyson Jane","family":"Bond","sequence":"additional","affiliation":[{"name":"Department of Addiction Institute of Psychiatry, Psychology and Neuroscience  London UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Chau Kiu Raymond","family":"Chan","sequence":"additional","affiliation":[{"name":"Institute of Psychology Chinese Academy of Sciences  Beijing China"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2016,4,5]]},"reference":[{"key":"e_1_2_7_2_1","doi-asserted-by":"publisher","DOI":"10.1080\/11038120802022102"},{"key":"e_1_2_7_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.psychres.2005.09.005"},{"key":"e_1_2_7_4_1","doi-asserted-by":"publisher","DOI":"10.1080\/17470910802319710"},{"key":"e_1_2_7_5_1","doi-asserted-by":"publisher","DOI":"10.1093\/oxfordjournals.schbul.a006925"},{"key":"e_1_2_7_6_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa051688"},{"key":"e_1_2_7_7_1","first-page":"649","article-title":"The CATIE and CUtLASS studies in schizophrenia: Results and implications for clinicians","volume":"23","author":"Naber D","year":"2009","journal-title":"CNS Drugs"},{"key":"e_1_2_7_8_1","first-page":"75","volume-title":"Handbook of Social Captial","author":"Petersen MB","year":"2009"},{"key":"e_1_2_7_9_1","doi-asserted-by":"publisher","DOI":"10.1177\/002076409303900305"},{"key":"e_1_2_7_10_1","doi-asserted-by":"publisher","DOI":"10.4103\/1119-3077.84007"},{"key":"e_1_2_7_11_1","doi-asserted-by":"publisher","DOI":"10.1080\/17470911003589309"},{"key":"e_1_2_7_12_1","doi-asserted-by":"crossref","first-page":"225","DOI":"10.1097\/01.jcp.0000117424.05703.29","article-title":"Overt aggression and psychotic symptoms in patients with schizophrenia treated with clozapine, olanzapine, risperidone, or haloperidol","volume":"24","author":"Volavks J","year":"2004","journal-title":"J. Clin. Psychopharmcol."},{"key":"e_1_2_7_13_1","doi-asserted-by":"crossref","first-page":"1918","DOI":"10.1176\/ajp.2006.163.11.1918","article-title":"Improvement in social competence with short\u2010term atypical antipsychotic treatment: A randomized, double\u2010blind comparison of quetiapine versus risperidone for social competence, social cognition, and neuropsychological functioning","volume":"163","author":"Harvey PD","year":"2006","journal-title":"Am. J. Psychiatry"},{"key":"e_1_2_7_14_1","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.1216841110"},{"key":"e_1_2_7_15_1","doi-asserted-by":"publisher","DOI":"10.1097\/00004583-200209000-00002"},{"key":"e_1_2_7_16_1","doi-asserted-by":"publisher","DOI":"10.1186\/1744-9081-5-6"},{"key":"e_1_2_7_17_1","doi-asserted-by":"publisher","DOI":"10.1176\/ajp.155.3.373"},{"key":"e_1_2_7_18_1","doi-asserted-by":"publisher","DOI":"10.1055\/s-2006-948328"},{"key":"e_1_2_7_19_1","doi-asserted-by":"publisher","DOI":"10.1176\/appi.books.9780890423349"},{"key":"e_1_2_7_20_1","volume-title":"Structured Clinical Interview for DSM\u2010IV\u2010TR Axis I Disorders, Research Version, Patient Edition. (SCID\u2010I\/P)","author":"Michael B","year":"2002"},{"key":"e_1_2_7_21_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.schres.2013.06.030"},{"key":"e_1_2_7_22_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.biopsych.2009.08.040"},{"key":"e_1_2_7_23_1","doi-asserted-by":"publisher","DOI":"10.1093\/schbul\/13.2.261"},{"key":"e_1_2_7_24_1","doi-asserted-by":"publisher","DOI":"10.1037\/0022-3514.43.6.1306"},{"key":"e_1_2_7_25_1","doi-asserted-by":"publisher","DOI":"10.1037\/0021-843X.85.2.186"},{"key":"e_1_2_7_26_1","volume-title":"Behavioural Assessment of the Dysexecutive Syndrome","author":"Wilson BA","year":"1996"},{"key":"e_1_2_7_27_1","doi-asserted-by":"publisher","DOI":"10.1207\/s15327752jpa5503&4_17"},{"key":"e_1_2_7_28_1","first-page":"79","article-title":"Social cognition and atypical antipsychotic agents in the treatment of persons with schizophrenia: Preliminary data from a naturalistic study","volume":"154","author":"Mazza M","year":"2003","journal-title":"Clin. Ter."},{"key":"e_1_2_7_29_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.psychres.2010.04.015"},{"key":"e_1_2_7_30_1","doi-asserted-by":"publisher","DOI":"10.1097\/00131746-200401000-00002"},{"key":"e_1_2_7_31_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.psychres.2010.03.015"}],"container-title":["Psychiatry and Clinical Neurosciences"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fpcn.12382","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/pcn.12382","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,1]],"date-time":"2023-10-01T08:22:06Z","timestamp":1696148526000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/pcn.12382"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2016,4,5]]},"references-count":30,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2016,5]]}},"alternative-id":["10.1111\/pcn.12382"],"URL":"https:\/\/doi.org\/10.1111\/pcn.12382","archive":["Portico"],"relation":{},"ISSN":["1323-1316","1440-1819"],"issn-type":[{"value":"1323-1316","type":"print"},{"value":"1440-1819","type":"electronic"}],"subject":[],"published":{"date-parts":[[2016,4,5]]}}}