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All participants had their decision\u2010making abilities assessed using the Iowa Gambling Task (IGT<\/jats:styled-content>). Their eating\u2010related pathophysiology and depressive\/anxiety symptoms were also evaluated.<\/jats:p><\/jats:sec>Results<\/jats:title>The MMP<\/jats:styled-content>\u20109 level in AN<\/jats:styled-content> was significantly lower than that in either BN<\/jats:styled-content> or HC<\/jats:styled-content>, but the serum levels of proBDNF<\/jats:styled-content> and mBDNF<\/jats:styled-content> did not differ among the three groups. Investigation of the serum levels of proBDNF<\/jats:styled-content> and MMP<\/jats:styled-content>\u20109 in patients with ED<\/jats:styled-content> and controls revealed a significant correlation between them. In the BN<\/jats:styled-content>, there were positive correlations between mBDNF<\/jats:styled-content> level and IGT<\/jats:styled-content> performance and also between MMP\u20109<\/jats:styled-content> level and IGT<\/jats:styled-content> performance, but these correlations did not occur in AN<\/jats:styled-content>. The MMP<\/jats:styled-content>\u20109 level was positively associated with the Symptom Scale, one of the subscales of the Bulimic Investigatory Test, Edinburgh, only in AN<\/jats:styled-content>.<\/jats:p><\/jats:sec>Conclusion<\/jats:title>These results suggest that the serum level of MMP<\/jats:styled-content>\u20109 plays a role in the pathophysiology of AN<\/jats:styled-content>, and both the serum levels of mBDNF<\/jats:styled-content> and MMP<\/jats:styled-content>\u20109 may be associated with decision\u2010making abilities in patients with BN<\/jats:styled-content>.<\/jats:p><\/jats:sec>","DOI":"10.1111\/pcn.12490","type":"journal-article","created":{"date-parts":[[2016,11,28]],"date-time":"2016-11-28T08:42:51Z","timestamp":1480322571000},"page":"124-134","source":"Crossref","is-referenced-by-count":17,"title":["Altered serum level of matrix metalloproteinase\u20109 and its association with decision\u2010making in eating 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