{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,28]],"date-time":"2026-09-28T02:20:10Z","timestamp":1790562010077,"version":"4.1.0"},"reference-count":33,"publisher":"Wiley","issue":"10","license":[{"start":{"date-parts":[[2017,7,7]],"date-time":"2017-07-07T00:00:00Z","timestamp":1499385600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/501100003710","name":"Korea Health Industry Development Institute","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100003710","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Psychiatry Clin Neurosci"],"published-print":{"date-parts":[[2017,10]]},"abstract":"<jats:sec><jats:title>Aim<\/jats:title><jats:p>The current cut\u2010off score of the Korean version of the Childhood Autism Rating Scale (K\u2010CARS) does not seem to be sensitive enough to precisely diagnose high\u2010functioning autism. The aim of this study was to identify the optimal cut\u2010off score of K\u2010CARS for diagnosing high\u2010functioning individuals with autism spectrum disorders (ASD).<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>A total of 329 participants were assessed by the Korean versions of the Autism Diagnostic Interview \u2013 Revised (K\u2010ADI\u2010R), Autism Diagnostic Observation Schedule (K\u2010ADOS), and K\u2010CARS. IQ and Social Maturity Scale scores were also obtained.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>The true positive and false negative rates of K\u2010CARS were 77.2% and 22.8%, respectively. Verbal IQ (VIQ) and Social Quotient (SQ) were significant predictors of misclassification. The false negative rate increased to 36.0% from 19.8% when VIQ was &gt;69.5, and the rate increased to 44.1% for participants with VIQ\u2009&gt;\u200969.5 and SQ\u2009&gt;\u200975.5. In addition, if SQ\u2009was &gt;83.5, the false negative rate increased to 46.7%, even if the participant\u2019s VIQ was\u2009\u226469.5. Optimal cut\u2010off scores were 28.5 (for VIQ\u2009\u2264\u200969.5 and SQ\u2009\u2264\u200975.5), 24.25 (for VIQ\u2009&gt;\u200969.5 and SQ\u2009&gt;\u200975.5), and 24.5 (for SQ\u2009&gt;\u200983.5), respectively.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>The likelihood of a false negative error increases when K\u2010CARS is used to diagnose high\u2010functioning autism and Asperger's syndrome. For subjects with ASD and substantial verbal ability, the cut\u2010off score for K\u2010CARS should be re\u2010adjusted and\/or supplementary diagnostic tools might be needed to enhance diagnostic accuracy for ASD.<\/jats:p><\/jats:sec>","DOI":"10.1111\/pcn.12540","type":"journal-article","created":{"date-parts":[[2017,5,26]],"date-time":"2017-05-26T08:36:40Z","timestamp":1495787800000},"page":"725-732","source":"Crossref","is-referenced-by-count":17,"title":["Re\u2010adjusting the cut\u2010off score of the <scp>K<\/scp>orean version of the <scp>C<\/scp>hildhood <scp>A<\/scp>utism <scp>R<\/scp>ating <scp>S<\/scp>cale for high\u2010functioning individuals with autism spectrum disorder"],"prefix":"10.1111","volume":"71","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-5217-1253","authenticated-orcid":false,"given":"Hyuk\u2010Jin","family":"Kwon","sequence":"first","affiliation":[{"name":"Department of Psychiatry Seoul National University Bundang Hospital, Seoul National University College of Medicine  Seongnam Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hee\u2010Jeong","family":"Yoo","sequence":"additional","affiliation":[{"name":"Department of Psychiatry Seoul National University Bundang Hospital, Seoul National University College of Medicine  Seongnam Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Joo\u2010Hyun","family":"Kim","sequence":"additional","affiliation":[{"name":"Department of Psychiatry Seoul National University Bundang Hospital, Seoul National University College of Medicine  Seongnam Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dong\u2010Hyun","family":"Noh","sequence":"additional","affiliation":[{"name":"Department of Psychiatry Seoul National University Bundang Hospital, Seoul National University College of Medicine  Seongnam Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hyun\u2010Jung","family":"Sunwoo","sequence":"additional","affiliation":[{"name":"Department of Psychiatry Seoul National University Bundang Hospital, Seoul National University College of Medicine  Seongnam Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ye Seul","family":"Jeon","sequence":"additional","affiliation":[{"name":"Department of Psychiatry Seoul National University Bundang Hospital, Seoul National University College of Medicine  Seongnam Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sang\u2010youn","family":"Lee","sequence":"additional","affiliation":[{"name":"Department of Psychiatry Seoul National University Bundang Hospital, Seoul National University College of Medicine  Seongnam Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ye\u2010ul","family":"Jo","sequence":"additional","affiliation":[{"name":"Department of Psychiatry Seoul National University Bundang Hospital, Seoul National University College of Medicine  Seongnam Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gui\u2010Young","family":"Bong","sequence":"additional","affiliation":[{"name":"Department of Psychiatry Seoul National University Bundang Hospital, Seoul National University College of Medicine  Seongnam Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2017,7,7]]},"reference":[{"key":"e_1_2_8_2_1","doi-asserted-by":"publisher","DOI":"10.1176\/appi.books.9780890425596"},{"key":"e_1_2_8_3_1","doi-asserted-by":"publisher","DOI":"10.1044\/0161-1461(2003\/015)"},{"key":"e_1_2_8_4_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10803-006-0128-8"},{"key":"e_1_2_8_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jpeds.2008.09.012"},{"key":"e_1_2_8_6_1","doi-asserted-by":"publisher","DOI":"10.1177\/10983007050070040601"},{"key":"e_1_2_8_7_1","doi-asserted-by":"publisher","DOI":"10.1542\/peds.2009-0958"},{"key":"e_1_2_8_8_1","first-page":"167","article-title":"A study of support system for facilitating early diagnosis and intervention for young children with autism spectrum disorders: Based on the experiences and the perceptions of parents","volume":"13","author":"Lee S","year":"2013","journal-title":"J. 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