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Searching PubMed and PsycINFO, we conducted the first systematic review of randomized\u2010controlled trials (RCTs) investigating the efficacy of behavioral IBIs at improving interoception and target symptoms of mental disorders in comparison to a non\u2010interoception\u2010based control condition [CRD42021297993]. Thirty\u2010one RCTs fulfilled inclusion criteria. Across all studies, a pattern emerged with 20 (64.5%) RCTs demonstrating IBIs to be more efficacious at improving interoception compared to control conditions. The most promising results were found for post\u2010traumatic stress disorder, irritable bowel syndrome, fibromyalgia and substance use disorders. Regarding symptom improvement, the evidence was inconclusive. The IBIs were heterogenous in their approach to improving interoception. The quality of RCTs was moderate to good. In conclusion, IBIs are potentially efficacious at improving interoception for some mental disorders. In terms of symptom reduction, the evidence is less promising. Future research on the efficacy of IBIs is needed.<\/jats:p>","DOI":"10.1111\/pcn.13576","type":"journal-article","created":{"date-parts":[[2023,7,8]],"date-time":"2023-07-08T10:19:30Z","timestamp":1688811570000},"page":"530-540","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":67,"title":["Psychological interventions for interoception in mental health disorders: A systematic review of randomized\u2010controlled trials"],"prefix":"10.1111","volume":"77","author":[{"given":"Nikolas","family":"Heim","sequence":"first","affiliation":[{"name":"International Psychoanalytic University Berlin  Berlin Germany"},{"name":"Wellcome Centre for Human Neuroimaging, University College London  London UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1875-309X","authenticated-orcid":false,"given":"Marina","family":"Bobou","sequence":"additional","affiliation":[{"name":"Research Department of Clinical, Educational and Health Psychology University College London  London UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michal","family":"Tanzer","sequence":"additional","affiliation":[{"name":"Research Department of Clinical, Educational and Health Psychology University College London  London UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Paul M.","family":"Jenkinson","sequence":"additional","affiliation":[{"name":"Institute for Social Neuroscience  Melbourne Victoria Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christiane","family":"Steinert","sequence":"additional","affiliation":[{"name":"International Psychoanalytic University Berlin  Berlin Germany"},{"name":"Department of Psychosomatics and Psychotherapy Justus\u2010Liebig\u2010University Giessen  Giessen Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Aikaterini","family":"Fotopoulou","sequence":"additional","affiliation":[{"name":"Research Department of Clinical, Educational and Health Psychology University College London  London UK"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2023,8,9]]},"reference":[{"key":"e_1_2_8_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.biopsycho.2022.108262"},{"key":"e_1_2_8_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.tins.2020.09.011"},{"key":"e_1_2_8_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0959-4388(03)00090-4"},{"key":"e_1_2_8_5_1","first-page":"102","volume-title":"The Cutaneous Borders of Interoception: Active and Social Inference of Pain and Pleasure on the Skin. 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