{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,1]],"date-time":"2026-10-01T06:31:40Z","timestamp":1790836300723,"version":"4.1.0"},"reference-count":39,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2023,12,15]],"date-time":"2023-12-15T00:00:00Z","timestamp":1702598400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"funder":[{"DOI":"10.13039\/100009619","name":"Japan Agency for Medical Research and Development","doi-asserted-by":"publisher","award":["JP22dk0307098"],"award-info":[{"award-number":["JP22dk0307098"]}],"id":[{"id":"10.13039\/100009619","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Psychiatry Clin Neurosci"],"published-print":{"date-parts":[[2024,4]]},"abstract":"<jats:sec>\n                    <jats:title>Aim<\/jats:title>\n                    <jats:p>\n                      Live two\u2010way video, easily accessible from home\n                      <jats:italic>via<\/jats:italic>\n                      smartphones and other devices, is becoming a new way of providing psychiatric treatment. However, lack of evidence for real\u2010world clinical setting effectiveness hampers its approval by medical insurance in some countries. Here, we conducted the first large\u2010scale pragmatic, randomized controlled trial to determine the effectiveness of long\u2010term treatment for multiple psychiatric disorders\n                      <jats:italic>via<\/jats:italic>\n                      two\u2010way video using smartphones and other devices, which are currently the primary means of telecommunication.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>\n                      This randomized controlled trial compared two\u2010way video\n                      <jats:italic>versus<\/jats:italic>\n                      face\u2010to\u2010face treatment for depressive disorder, anxiety disorder, and obsessive\u2010compulsive disorder in the subacute\/maintenance phase during a 24\u2010week period. Adult patients with the above\u2010mentioned disorders were allocated to either a two\u2010way video group (\u226550% video sessions) or a face\u2010to\u2010face group (100% in\u2010person sessions) and received standard treatment covered by public medical insurance. The primary outcome was the 36\u2010Item Short\u2010Form Health Survey Mental Component Summary (SF\u201036 MCS) score. Secondary outcomes included all\u2010cause discontinuation, working alliance, adverse events, and the severity rating scales for each disorder.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      A total of 199 patients participated in this study. After 24\u2009weeks of treatment, two\u2010way video treatment was found to be noninferior to face\u2010to\u2010face treatment regarding SF\u201036 MCS score (48.50 vs 46.68, respectively;\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&lt;\u20090.001). There were no significant differences between the groups regarding most secondary end points, including all\u2010cause discontinuation, treatment efficacy, and satisfaction.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>Two\u2010way video treatment using smartphones and other devices, was noninferior to face\u2010to\u2010face treatment in real\u2010world clinical settings. Modern telemedicine, easily accessible from home, can be used as a form of health care.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/pcn.13618","type":"journal-article","created":{"date-parts":[[2023,12,16]],"date-time":"2023-12-16T02:00:33Z","timestamp":1702692033000},"page":"220-228","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":24,"title":["Live two\u2010way video versus\n                    <scp>face\u2010to\u2010face<\/scp>\n                    treatment for depression, anxiety, and\n                    <scp>obsessive\u2010compulsive<\/scp>\n                    disorder: A\n                    <scp>24\u2010week<\/scp>\n                    randomized controlled trial"],"prefix":"10.1111","volume":"78","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-0557-8648","authenticated-orcid":false,"given":"Taishiro","family":"Kishimoto","sequence":"first","affiliation":[{"name":"Hills Joint Research Laboratory for 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Medicine  Tokyo Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2626-8123","authenticated-orcid":false,"given":"Mitsuhiro","family":"Sado","sequence":"additional","affiliation":[{"name":"Department of Neuropsychiatry Keio University School of Medicine  Tokyo Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Akihiro","family":"Takamiya","sequence":"additional","affiliation":[{"name":"Hills Joint Research Laboratory for Future Preventive Medicine and Wellness Keio University School of Medicine  Tokyo Japan"},{"name":"Department of Neuropsychiatry Keio University School of Medicine  Tokyo Japan"},{"name":"Akasaka Clinic  Tokyo Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3874-5273","authenticated-orcid":false,"given":"Masaru","family":"Mimura","sequence":"additional","affiliation":[{"name":"Department of Neuropsychiatry Keio University School of Medicine  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