{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,23]],"date-time":"2026-06-23T00:58:44Z","timestamp":1782176324527,"version":"3.54.5"},"reference-count":29,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2012,12,28]],"date-time":"2012-12-28T00:00:00Z","timestamp":1356652800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Pediatric Dermatology"],"published-print":{"date-parts":[[2013,3]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Follicular mucinosis (<jats:styled-content style=\"fixed-case\">FM<\/jats:styled-content>) and folliculotropic mycosis fungoides (<jats:styled-content style=\"fixed-case\">MF<\/jats:styled-content>) are rare in children, and data regarding long\u2010term outcomes are limited. We sought to describe clinical and histopathologic findings of children with <jats:styled-content style=\"fixed-case\">FM<\/jats:styled-content> with and without <jats:styled-content style=\"fixed-case\">MF<\/jats:styled-content>, as well as treatments administered and clinical outcomes. We conducted a retrospective chart review of patients younger than 22 years (at time of diagnosis) with a biopsy demonstrating <jats:styled-content style=\"fixed-case\">FM<\/jats:styled-content> who were seen in the <jats:styled-content style=\"fixed-case\">D<\/jats:styled-content>ermatology <jats:styled-content style=\"fixed-case\">D<\/jats:styled-content>epartment at the <jats:styled-content style=\"fixed-case\">M<\/jats:styled-content>ayo <jats:styled-content style=\"fixed-case\">C<\/jats:styled-content>linic from <jats:styled-content style=\"fixed-case\">S<\/jats:styled-content>eptember 1, 1999, to <jats:styled-content style=\"fixed-case\">S<\/jats:styled-content>eptember 1, 2010. Eleven patients (six male, five female) ages 11 to 19 years at the time of diagnosis met the inclusion criteria. Follow\u2010up data were available for 10 patients, with a mean duration of 4.9\u00a0years. The head, neck, and extremities were the most common sites of involvement, and lesions were follicular\u2010based papules (18%), scaly alopecic patches and plaques (45%), or a combination of the two (36%). Overall, three patients were confirmed to have <jats:styled-content style=\"fixed-case\">MF<\/jats:styled-content>. <jats:styled-content style=\"fixed-case\">T<\/jats:styled-content>\u2010cell receptor gene rearrangement demonstrated clonality in two cases and was equivocal in one case. Treatments included topical corticosteroids, topical retinoids, oral minocycline, and, in patients with <jats:styled-content style=\"fixed-case\">MF<\/jats:styled-content>, ultraviolet light and topical bexarotene. Lesions resolved completely in seven patients, partially in one, and not at all in two (no follow\u2010up data on one patient). Of the three patients with <jats:styled-content style=\"fixed-case\">MF<\/jats:styled-content>, two had complete resolution, and one has intermittent flares. To our knowledge, no patients developed other lymphoproliferative disorders. <jats:styled-content style=\"fixed-case\">FM<\/jats:styled-content> in children is rare. A histopathologic diagnosis of <jats:styled-content style=\"fixed-case\">FM<\/jats:styled-content> does not equate to folliculotropic <jats:styled-content style=\"fixed-case\">MF<\/jats:styled-content> in all cases. Most patients responded to treatment with topical steroids, topical retinoids, or phototherapy. In our series of patients, the disease ran a benign course.<\/jats:p>","DOI":"10.1111\/pde.12019","type":"journal-article","created":{"date-parts":[[2012,12,28]],"date-time":"2012-12-28T07:23:12Z","timestamp":1356679392000},"page":"192-198","source":"Crossref","is-referenced-by-count":44,"title":["Pediatric Follicular Mucinosis: Presentation, Histopathology, Molecular Genetics, Treatment, and Outcomes over an 11\u2010Year Period at the Mayo Clinic"],"prefix":"10.1111","volume":"30","author":[{"given":"Ali","family":"Alikhan","sequence":"first","affiliation":[{"name":"Department of Dermatology Mayo Clinic Rochester Minnesota"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"John","family":"Griffin","sequence":"additional","affiliation":[{"name":"Department of Dermatology Mayo Clinic Rochester Minnesota"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nicholas","family":"Nguyen","sequence":"additional","affiliation":[{"name":"Department of Dermatology Mayo Clinic Rochester Minnesota"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dawn Marie R.","family":"Davis","sequence":"additional","affiliation":[{"name":"Department of Dermatology Mayo Clinic Rochester Minnesota"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lawrence E.","family":"Gibson","sequence":"additional","affiliation":[{"name":"Department of Dermatology Mayo Clinic Rochester Minnesota"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2012,12,28]]},"reference":[{"key":"e_1_2_5_2_1","doi-asserted-by":"publisher","DOI":"10.1001\/archderm.1957.01550220027005"},{"key":"e_1_2_5_3_1","volume-title":"Dermatology","author":"Bolognia J","year":"2008"},{"key":"e_1_2_5_4_1","first-page":"1289","article-title":"Mucophanerosis interfollicularis et seboglandularis","volume":"136","author":"Braun\u2010Falco O","year":"1957","journal-title":"Dermatol Wochenschr"},{"key":"e_1_2_5_5_1","first-page":"27","article-title":"Mucinosis follicularis","volume":"10","author":"Jablonska S","year":"1959","journal-title":"Hautarzt"},{"key":"e_1_2_5_6_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2133.1969.tb14009.x"},{"key":"e_1_2_5_7_1","doi-asserted-by":"publisher","DOI":"10.1097\/00000372-200402000-00006"},{"key":"e_1_2_5_8_1","doi-asserted-by":"publisher","DOI":"10.1159\/000018131"},{"key":"e_1_2_5_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0190-9622(89)70055-4"},{"key":"e_1_2_5_10_1","doi-asserted-by":"publisher","DOI":"10.1001\/archderm.1962.01590040054007"},{"key":"e_1_2_5_11_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1525-1470.1988.tb00893.x"},{"key":"e_1_2_5_12_1","doi-asserted-by":"publisher","DOI":"10.1159\/000254633"},{"key":"e_1_2_5_13_1","doi-asserted-by":"crossref","first-page":"193","DOI":"10.1001\/archderm.1970.04000080065012","article-title":"Alopecia mucinosa. 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