{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,27]],"date-time":"2026-03-27T02:08:15Z","timestamp":1774577295199,"version":"3.50.1"},"reference-count":15,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2012,12,28]],"date-time":"2012-12-28T00:00:00Z","timestamp":1356652800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Pediatric Dermatology"],"published-print":{"date-parts":[[2014,7]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Phylloid hypermelanosis is a less clearly defined pigmentary disturbance than its hypopigmented counterpart, phylloid hypomelanosis. We report the case of a 32\u2010month\u2010old boy who had multiple melanotic macules arranged in a typical phylloid pattern since birth. He also had an abnormal facial appearance, with macrocephaly, frontal bossing, hypertelorism, internal strabismus, and auricular deformities. Psychomotor delay, multiple cystic brain lesions, and bilateral sensorineural hearing loss were also found. A review of associated anomalies as described in this and five previously reported patients with phylloid hypermelanosis shows some vague and inconsistent similarities, such as unusual facial appearance, malformed ears, hearing loss, and mental deficiency, but it is likely that phylloid hypermelanosis represents a class of heterogeneous phenotypes. Future clinical and genetic research may show how many distinct entities can be placed in this group of disorders.<\/jats:p>","DOI":"10.1111\/pde.12053","type":"journal-article","created":{"date-parts":[[2012,12,28]],"date-time":"2012-12-28T10:21:25Z","timestamp":1356690085000},"page":"504-506","source":"Crossref","is-referenced-by-count":13,"title":["Phylloid Hypermelanosis: A Cutaneous Marker of Several Different Disorders?"],"prefix":"10.1111","volume":"31","author":[{"given":"Rudolf","family":"Happle","sequence":"first","affiliation":[{"name":"Department of Dermatology Freiburg University Medical Center Freiburg Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mario F.","family":"Franco\u2010Gu\u00edo","sequence":"additional","affiliation":[{"name":"Department of Dermatology University of Caldas Manizales Colombia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Germ\u00e1n","family":"Santacoloma\u2010Osorio","sequence":"additional","affiliation":[{"name":"Department of Dermatology University of Caldas Manizales Colombia"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2012,12,28]]},"reference":[{"key":"e_1_2_4_2_1","first-page":"170","article-title":"Pigmentary patterns associated with human mosaicism: a proposed classification","volume":"3","author":"Happle R","year":"1993","journal-title":"Eur J Dermatol"},{"key":"e_1_2_4_3_1","first-page":"511","article-title":"Phylloid hypomelanosis is closely related to mosaic trisomy 13","volume":"10","author":"Happle R","year":"2000","journal-title":"Eur J Dermatol"},{"key":"e_1_2_4_4_1","doi-asserted-by":"publisher","DOI":"10.1002\/ajmg.a.32758"},{"key":"e_1_2_4_5_1","doi-asserted-by":"publisher","DOI":"10.1001\/archdermatol.2009.37"},{"key":"e_1_2_4_6_1","doi-asserted-by":"publisher","DOI":"10.1159\/000277313"},{"key":"e_1_2_4_7_1","doi-asserted-by":"publisher","DOI":"10.1159\/000277273"},{"key":"e_1_2_4_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0190-9622(88)70269-8"},{"key":"e_1_2_4_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaad.2008.09.017"},{"key":"e_1_2_4_10_1","doi-asserted-by":"publisher","DOI":"10.1007\/s001050051253"},{"key":"e_1_2_4_11_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1525-1470.1997.tb00956.x"},{"key":"e_1_2_4_12_1","doi-asserted-by":"publisher","DOI":"10.1097\/00019605-199807000-00006"},{"key":"e_1_2_4_13_1","doi-asserted-by":"publisher","DOI":"10.1159\/000051593"},{"key":"e_1_2_4_14_1","doi-asserted-by":"publisher","DOI":"10.1002\/1096-8628(20010115)98:2<145::AID-AJMG1023>3.0.CO;2-7"},{"key":"e_1_2_4_15_1","first-page":"48","article-title":"Sur un syndrome pigmentaire cong\u00e9nital, proche de l'incontinentia pigmenti (Bloch\u2010Sulzberger) avec oligophr\u00e9nie et malfomations ost\u00e9o\u2010articulaires multiples","volume":"95","author":"Dockx SW","year":"1956","journal-title":"Rev Neurol (Paris)"},{"key":"e_1_2_4_16_1","doi-asserted-by":"publisher","DOI":"10.2340\/00015555-1259"}],"container-title":["Pediatric Dermatology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fpde.12053","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/pde.12053","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,23]],"date-time":"2023-09-23T13:56:57Z","timestamp":1695477417000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/pde.12053"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2012,12,28]]},"references-count":15,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2014,7]]}},"alternative-id":["10.1111\/pde.12053"],"URL":"https:\/\/doi.org\/10.1111\/pde.12053","archive":["Portico"],"relation":{},"ISSN":["0736-8046","1525-1470"],"issn-type":[{"value":"0736-8046","type":"print"},{"value":"1525-1470","type":"electronic"}],"subject":[],"published":{"date-parts":[[2012,12,28]]}}}