{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,27]],"date-time":"2026-02-27T20:15:50Z","timestamp":1772223350407,"version":"3.50.1"},"reference-count":28,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2013,1,7]],"date-time":"2013-01-07T00:00:00Z","timestamp":1357516800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Pediatric Dermatology"],"published-print":{"date-parts":[[2013,5]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>\n                    Vitamin D is believed to affect the progression and severity of atopic dermatitis (\n                    <jats:styled-content style=\"fixed-case\">AD<\/jats:styled-content>\n                    ). Allergic sensitization may cause this effect to vary. Individuals who fulfilled the Hanifin and Rajka criteria for\n                    <jats:styled-content style=\"fixed-case\">AD<\/jats:styled-content>\n                    underwent epidermal prick tests and blood tests for specific immunoglobulin E(IgE), serum total IgE, 25\u2010hydroxy vitamin D, and peripheral blood eosinophil count and percentage. Disease severity was determined according to the\n                    <jats:styled-content style=\"fixed-case\">Scoring<\/jats:styled-content>\n                    Atopic Dermatitis (\n                    <jats:styled-content style=\"fixed-case\">SCORAD<\/jats:styled-content>\n                    ) index. Patients were grouped according to allergic sensitization. Seventy\u2010three children with\n                    <jats:styled-content style=\"fixed-case\">AD<\/jats:styled-content>\n                    (median age 33.0\u00a0mos, interquartile range 19.0\u201361.5\u00a0mos) were enrolled in the study; 33 (45.2%) were found to have allergic sensitization. In this group there was a negative correlation between\n                    <jats:styled-content style=\"fixed-case\">SCORAD<\/jats:styled-content>\n                    score and serum vitamin D level (p\u00a0=\u00a00.047, correlation coefficient [r]\u00a0=\u00a0\u22120.349), whereas there was no correlation in the group without sensitization (p\u00a0=\u00a00.30, r\u00a0=\u00a0\u22120.168). Vitamin D was not correlated with total IgE and eosinophil percentage in either\n                    <jats:styled-content style=\"fixed-case\">AD<\/jats:styled-content>\n                    group (p\u00a0=\u00a00.77, r\u00a0=\u00a00.054 and p\u00a0=\u00a00.73, r\u00a0=\u00a0\u22120.062, respectively). Vitamin D may affect the severity of\n                    <jats:styled-content style=\"fixed-case\">AD<\/jats:styled-content>\n                    , especially in children with allergic sensitization.\n                  <\/jats:p>","DOI":"10.1111\/pde.12058","type":"journal-article","created":{"date-parts":[[2013,1,7]],"date-time":"2013-01-07T04:58:40Z","timestamp":1357534720000},"page":"359-363","source":"Crossref","is-referenced-by-count":49,"title":["Vitamin D Level in Children Is Correlated with Severity of Atopic Dermatitis but Only in Patients with Allergic Sensitizations"],"prefix":"10.1111","volume":"30","author":[{"given":"Aysegul","family":"Akan","sequence":"first","affiliation":[{"name":"Department of Pediatric Allergy and Immunology Ankara Children's Hematology Oncology Education and Research Hospital Ankara Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Dilek","family":"Azkur","sequence":"additional","affiliation":[{"name":"Department of Pediatric Allergy and Immunology Ankara Children's Hematology Oncology Education and Research Hospital Ankara Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tayfur","family":"Ginis","sequence":"additional","affiliation":[{"name":"Department of Pediatric Allergy and Immunology Ankara Children's Hematology Oncology Education and Research Hospital Ankara Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Muge","family":"Toyran","sequence":"additional","affiliation":[{"name":"Department of Pediatric Allergy and Immunology Ankara Children's Hematology Oncology Education and Research Hospital Ankara Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Aysenur","family":"Kaya","sequence":"additional","affiliation":[{"name":"Department of Pediatric Allergy and Immunology Ankara Children's Hematology Oncology Education and Research Hospital Ankara 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