{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,7]],"date-time":"2025-11-07T09:00:23Z","timestamp":1762506023675},"reference-count":20,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2012,12,28]],"date-time":"2012-12-28T00:00:00Z","timestamp":1356652800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Pediatric Dermatology"],"published-print":{"date-parts":[[2013,9]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>In contrast to adolescent acne, infantile acne (<jats:styled-content style=\"fixed-case\">IA<\/jats:styled-content>) is a rare condition with only a limited body of available literature. In this descriptive, retrospective study, we reviewed six cases from 2002 to 2010 treated with oral isotretinoin. The average age of onset was 6.16\u00a0months (range 0\u201321 mos). Consistent with the previous, limited literature, we found predominantly boys are affected, a predilection for the cheeks, and a polymorphic inflammatory morphology. Two patients had a family history of acne. All cases were successfully and safely treated with oral isotretinoin. The suggested treatment of childhood acne is similar to that of adolescents (graded according to the severity of the skin disease and risk of scarring). Oral isotretinoin appears to be an effective and safe treatment for severe <jats:styled-content style=\"fixed-case\">IA<\/jats:styled-content>.<\/jats:p>","DOI":"10.1111\/pde.12069","type":"journal-article","created":{"date-parts":[[2012,12,28]],"date-time":"2012-12-28T10:21:35Z","timestamp":1356690095000},"page":"513-518","source":"Crossref","is-referenced-by-count":19,"title":["Infantile Acne Treated with Oral Isotretinoin"],"prefix":"10.1111","volume":"30","author":[{"given":"Iben Marie","family":"Miller","sequence":"first","affiliation":[{"name":"Department of Dermatology Roskilde Hospital Health Sciences Faculty University of Copenhagen Copenhagen Denmark"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Bego\u00f1a","family":"Echeverr\u00eda","sequence":"additional","affiliation":[{"name":"Department of Pediatric Dermatology Hospital del Ni\u00f1o Jesus Madrid Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Antonio","family":"Torrelo","sequence":"additional","affiliation":[{"name":"Department of Pediatric Dermatology Hospital del Ni\u00f1o Jesus Madrid Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gregor Borut Ernst","family":"Jemec","sequence":"additional","affiliation":[{"name":"Department of Dermatology Roskilde Hospital Health Sciences Faculty University of Copenhagen Copenhagen Denmark"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2012,12,28]]},"reference":[{"key":"e_1_2_5_2_1","doi-asserted-by":"publisher","DOI":"10.1159\/000057878"},{"key":"e_1_2_5_3_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0625.2009.00890.x"},{"key":"e_1_2_5_4_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1525-1470.2009.00932.x"},{"key":"e_1_2_5_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.clindermatol.2004.03.001"},{"key":"e_1_2_5_6_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2230.1990.tb02119.x"},{"key":"e_1_2_5_7_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1525-1470.2005.22417.x"},{"key":"e_1_2_5_8_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1525-1470.2008.00755.x"},{"key":"e_1_2_5_9_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2133.2001.04397.x"},{"key":"e_1_2_5_10_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1525-1470.1991.tb00311.x"},{"key":"e_1_2_5_11_1","first-page":"71","article-title":"Treatment of an infantile acne with oral isotretinoin","volume":"14","author":"Sarazin F","year":"2004","journal-title":"Eur J Dermatol"},{"key":"e_1_2_5_12_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1525-1470.2005.22224.x"},{"key":"e_1_2_5_13_1","doi-asserted-by":"crossref","first-page":"432","DOI":"10.1001\/archderm.1987.01660280032015","article-title":"Nodulocystic infantile acne occurring in a kindred of steatocystoma","volume":"123","author":"Burket JM","year":"1987","journal-title":"Arch Dermatol"},{"key":"e_1_2_5_14_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2133.1997.tb03678.x"},{"key":"e_1_2_5_15_1","first-page":"132","article-title":"[Infantile acne and isotretinoin]","volume":"125","author":"Leaute\u2010Labreze C","year":"1998","journal-title":"Ann Dermatol Venereol"},{"key":"e_1_2_5_16_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-3476(99)70255-6"},{"key":"e_1_2_5_17_1","first-page":"6856","article-title":"Acne neonatorum\/acne infantum","volume":"162","author":"Holm EA","year":"2000","journal-title":"Ugeskr Laeger"},{"key":"e_1_2_5_18_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaad.2005.11.1061"},{"key":"e_1_2_5_19_1","doi-asserted-by":"publisher","DOI":"10.1080\/09546630260199532"},{"key":"e_1_2_5_20_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM199910143411601"},{"key":"e_1_2_5_21_1","doi-asserted-by":"publisher","DOI":"10.1067\/mjd.2001.113721"}],"container-title":["Pediatric Dermatology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fpde.12069","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/pde.12069","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,29]],"date-time":"2023-09-29T22:50:11Z","timestamp":1696027811000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/pde.12069"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2012,12,28]]},"references-count":20,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2013,9]]}},"alternative-id":["10.1111\/pde.12069"],"URL":"https:\/\/doi.org\/10.1111\/pde.12069","archive":["Portico"],"relation":{},"ISSN":["0736-8046","1525-1470"],"issn-type":[{"value":"0736-8046","type":"print"},{"value":"1525-1470","type":"electronic"}],"subject":[],"published":{"date-parts":[[2012,12,28]]}}}