{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,1]],"date-time":"2026-05-01T05:29:36Z","timestamp":1777613376919,"version":"3.51.4"},"reference-count":9,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2013,4,8]],"date-time":"2013-04-08T00:00:00Z","timestamp":1365379200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Pediatric Dermatology"],"published-print":{"date-parts":[[2013,7]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Idiopathic facial aseptic granuloma (<jats:styled-content style=\"fixed-case\">IFAG<\/jats:styled-content>) is a disorder that usually occurs during early childhood. Its pathogenesis remains poorly understood. The objective of this study was to investigate possible relationships between <jats:styled-content style=\"fixed-case\">IFAG<\/jats:styled-content> and childhood rosacea. This was a retrospective multicenter study of patients attending four French dermatologic centers diagnosed with <jats:styled-content style=\"fixed-case\">IFAG<\/jats:styled-content> between October 2000 and July 2007. Patients and their parents were asked to come for a follow\u2010up visit or to make an appointment for a telephone interview. Clinical symptoms of childhood rosacea were recorded: flushing, permanent or recurrent erythema; facial telangiectasia; papules and pustules on the face without comedones or microcysts; preferential location of the lesions on the convexity of the face; and ophthalmologic involvement of rosacea (recurrent chalazions, conjunctival hyperemia, keratitis). Thirty\u2010eight patients, 20 girls and 18 boys, were included in the study. The median age at the time of diagnosis of <jats:styled-content style=\"fixed-case\">IFAG<\/jats:styled-content> was 43\u00a0months, with a median follow\u2010up of 3.9\u00a0years. Sixteen patients (42.1%) had at least two criteria of childhood rosacea, 11 of 32 (34.4%) with a single lesion and 5 of 6 (83.3%) with multiple lesions. Children with <jats:styled-content style=\"fixed-case\">IFAG<\/jats:styled-content> are at risk for childhood rosacea, and follow\u2010up is advised, including periodic ophthalmologic assessment.<\/jats:p>","DOI":"10.1111\/pde.12137","type":"journal-article","created":{"date-parts":[[2013,4,8]],"date-time":"2013-04-08T07:07:19Z","timestamp":1365404839000},"page":"429-432","source":"Crossref","is-referenced-by-count":40,"title":["<scp>IFAG<\/scp> and Childhood Rosacea: A Possible Link?"],"prefix":"10.1111","volume":"30","author":[{"given":"Sorilla","family":"Prey","sequence":"first","affiliation":[{"name":"Pediatric Dermatology Unit Pellegrin Children's Hospital Bordeaux France"},{"name":"University of Bordeaux Segalen Bordeaux France"},{"name":"Inserm U1035 Bordeaux France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Khaled","family":"Ezzedine","sequence":"additional","affiliation":[{"name":"Pediatric Dermatology Unit Pellegrin Children's Hospital Bordeaux France"},{"name":"University of Bordeaux Segalen Bordeaux France"},{"name":"Inserm U1035 Bordeaux France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Juliette","family":"Mazereeuw\u2010Hautier","sequence":"additional","affiliation":[{"name":"Dermatology Department Larrey Hospital Toulouse France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Catherine","family":"Eschard","sequence":"additional","affiliation":[{"name":"Dermatology Department CHU de Reims Reims France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"S\u00e9bastien","family":"Barbarot","sequence":"additional","affiliation":[{"name":"Dermatology Department CHU de Nantes Nantes France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Franck","family":"Boralevi","sequence":"additional","affiliation":[{"name":"Pediatric Dermatology Unit Pellegrin Children's Hospital Bordeaux France"},{"name":"University of Bordeaux Segalen Bordeaux France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Alain","family":"Ta\u00efeb","sequence":"additional","affiliation":[{"name":"Pediatric Dermatology Unit Pellegrin Children's Hospital Bordeaux France"},{"name":"University of Bordeaux Segalen Bordeaux France"},{"name":"Inserm U1035 Bordeaux France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Christine","family":"L\u00e9aute\u2010Labr\u00e8ze","sequence":"additional","affiliation":[{"name":"Pediatric Dermatology Unit Pellegrin Children's Hospital Bordeaux France"},{"name":"University of Bordeaux Segalen Bordeaux France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"name":"on behalf of the Groupe de Recherche Clinique en Dermatologie P\u00e9diatrique","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2013,4,8]]},"reference":[{"key":"e_1_2_5_2_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2133.2006.07741.x"},{"key":"e_1_2_5_3_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1525-1470.2011.01689.x"},{"key":"e_1_2_5_4_1","article-title":"Idiopathic facial aseptic granuloma in a child: a possible expression of childhood rosacea","author":"Baroni A","year":"2012","journal-title":"Pediatr Dermatol"},{"key":"e_1_2_5_5_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1529-8019.2006.00075.x"},{"key":"e_1_2_5_6_1","doi-asserted-by":"publisher","DOI":"10.1001\/archdermatol.2007.50"},{"key":"e_1_2_5_7_1","first-page":"9","article-title":"A toddler with facial nodules: a case of idiopathic facial aseptic granuloma","volume":"16","author":"Martinez\u2010Diaz GJ","year":"2010","journal-title":"Dermatol Online 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