{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,28]],"date-time":"2026-08-28T22:29:32Z","timestamp":1787956172522,"version":"build-2784847793"},"reference-count":19,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2013,11,13]],"date-time":"2013-11-13T00:00:00Z","timestamp":1384300800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Pediatric Dermatology"],"published-print":{"date-parts":[[2014,3]]},"abstract":"Abstract<\/jats:title>A growing number of dermatologists dispute the existence of infantile seborrheic dermatitis (ISD<\/jats:styled-content>) as an independent clinical entity. Therefore the aim of the present study was to estimate the epidemiologic features of ISD<\/jats:styled-content> in a defined population of G<\/jats:styled-content>reek children, assess its course, and identify associations, if any, with other common dermatoses of childhood. Children from the region of A<\/jats:styled-content>thens who were examined and diagnosed with typical clinical features of ISD<\/jats:styled-content> between 1997 and 2011 were included in the study. The relevant data were collected retrospectively from their medical records using a standardized form. Eighty\u2010seven children were enrolled (50 boys, 37 girls; mean age 3.1\u00a0mos at the time of ISD<\/jats:styled-content> diagnosis). The main body areas affected were the scalp and face for the majority of the children (78\/87), whereas the trunk and limbs were less frequently involved (9\/87). In all cases, erythema and scaling of affected patients were mild to moderate. Forty\u2010nine of the 87 children were followed up over a period of 5\u00a0years. Thirty children in this group developed features of atopic dermatitis (AD<\/jats:styled-content>) at a later stage, according to the UK<\/jats:styled-content> diagnostic criteria of AD<\/jats:styled-content>, and 23 of these children were diagnosed with AD<\/jats:styled-content>, at an average time interval of 6.4\u00a0months from ISD<\/jats:styled-content> onset, and seven presented with clinical features of AD<\/jats:styled-content> at the time of ISD<\/jats:styled-content> diagnosis. The remaining 19 children in the follow\u2010up group progressed without developing any other chronic skin disease, and all recovered within 6\u00a0months of its onset. Thirty\u2010eight had no further follow\u2010up after their initial ISD<\/jats:styled-content> diagnosis. In spite of the lack of information on the disease course for the last group, assuming they all recovered, the prevalence of AD<\/jats:styled-content> (34.4%) in our ISD<\/jats:styled-content> sample was significantly higher than the prevalence of AD<\/jats:styled-content> (10.7%) in the general population for the same age group, as shown in a previous study performed in the municipality of A<\/jats:styled-content>thens (p\u00a0<\u00a00.001). A significant number of children were found to develop AD<\/jats:styled-content> shortly after their ISD<\/jats:styled-content> diagnosis. This finding demonstrates a strong association in the clinical course between the two diseases or indicates that the two diseases may be in the same clinical spectrum. Further epidemiologic studies must be conducted to assess the significance of this finding.<\/jats:p>","DOI":"10.1111\/pde.12216","type":"journal-article","created":{"date-parts":[[2013,11,14]],"date-time":"2013-11-14T04:11:01Z","timestamp":1384402261000},"page":"125-130","source":"Crossref","is-referenced-by-count":46,"title":["Retrospective Analysis of the Relationship Between Infantile Seborrheic Dermatitis and Atopic Dermatitis"],"prefix":"10.1111","volume":"31","author":[{"given":"Alex","family":"Alexopoulos","sequence":"first","affiliation":[{"name":"First Department of Pediatrics University of Athens Aghia Sofia Children's Hospital Athens Greece"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Talia","family":"Kakourou","sequence":"additional","affiliation":[{"name":"First Department of Pediatrics University of Athens Aghia Sofia Children's Hospital Athens Greece"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Irene","family":"Orfanou","sequence":"additional","affiliation":[{"name":"First Department of Pediatrics University of Athens Aghia Sofia Children's Hospital Athens Greece"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Athina","family":"Xaidara","sequence":"additional","affiliation":[{"name":"First Department of Pediatrics University of Athens Aghia Sofia Children's Hospital Athens Greece"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"George","family":"Chrousos","sequence":"additional","affiliation":[{"name":"First Department of Pediatrics University of Athens Aghia Sofia Children's Hospital Athens Greece"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2013,11,13]]},"reference":[{"key":"e_1_2_5_2_1","first-page":"2344","article-title":"Seborrheic dermatitis","volume":"108","author":"Gee BC","year":"2004","journal-title":"Clin Evid"},{"key":"e_1_2_5_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0733-8635(03)00028-7"},{"key":"e_1_2_5_4_1","doi-asserted-by":"publisher","DOI":"10.1001\/archderm.139.3.318"},{"key":"e_1_2_5_5_1","doi-asserted-by":"publisher","DOI":"10.1097\/00006205-199706000-00003"},{"key":"e_1_2_5_6_1","first-page":"558","article-title":"Neonatal seborrheic dermatitis [letter]","volume":"142","author":"Leung AK","year":"1985","journal-title":"West J Med"},{"key":"e_1_2_5_7_1","first-page":"125","article-title":"Seborrheic dermatitis: an overview","volume":"74","author":"Schwartz RA","year":"2006","journal-title":"Am Fam Physician"},{"key":"e_1_2_5_8_1","doi-asserted-by":"crossref","first-page":"534","DOI":"10.2340\/0001555566534536","article-title":"Psoriasiform napkin dermatitis","volume":"66","author":"Rasmussen HB","year":"1986","journal-title":"Acta Derm Venereol"},{"key":"e_1_2_5_9_1","first-page":"17","volume-title":"Handbook of pediatric dermatology","author":"Harper J","year":"1990"},{"key":"e_1_2_5_10_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2133.1983.tb01074.x"},{"key":"e_1_2_5_11_1","first-page":"1","volume-title":"Textbook of dermatology","author":"Beare J","year":"1979"},{"key":"e_1_2_5_12_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2133.1994.tb08532.x"},{"key":"e_1_2_5_13_1","unstructured":"KakourouT TsiftisG KavadiasGet\u00a0al.Prevalence of atopic dermatitis among nursery school children in Athens. 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