{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,27]],"date-time":"2026-09-27T10:29:05Z","timestamp":1790504945650,"version":"4.1.0"},"reference-count":18,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2013,10,18]],"date-time":"2013-10-18T00:00:00Z","timestamp":1382054400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Pediatric Dermatology"],"published-print":{"date-parts":[[2014,5]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Vitiligo significantly affects quality of life (<jats:styled-content style=\"fixed-case\">QOL<\/jats:styled-content>) in adults, but little is known about the effect on <jats:styled-content style=\"fixed-case\">QOL<\/jats:styled-content> of pediatric vitiligo and whether the extent, distribution, and duration of vitiligo are associated with <jats:styled-content style=\"fixed-case\">QOL<\/jats:styled-content>. We performed an online parental questionnaire\u2010based study (<jats:italic>N<\/jats:italic>\u00a0=\u00a0350) regarding children ages 0 to 17 years with vitiligo, including validated questions about body surface area (<jats:styled-content style=\"fixed-case\">BSA<\/jats:styled-content>), distribution, and age of onset of vitiligo, associated symptoms, and <jats:styled-content style=\"fixed-case\">QOL<\/jats:styled-content> using the Children's Dermatology Life Quality Index (<jats:styled-content style=\"fixed-case\">CDLQI<\/jats:styled-content>). Vitiligo negatively affected numerous aspects of and total <jats:styled-content style=\"fixed-case\">CDLQI<\/jats:styled-content> score (median 3.0, interquartile range 5.0). Their vitiligo lesions did not bother only 4.1% of teenagers ages 15 to 17 years, versus 45.6% of children ages 0 to 6 years and 50.0% of those ages 7 to 14 years (p\u00a0&lt;\u00a00.001). There was no association between the child's age and whether the child's vitiligo bothered the parents (p\u00a0=\u00a00.27). The most bothersome sites of vitiligo lesions for children and parents were the face (25.6% and 37.4%, respectively) and legs (26.2% and 26.2%, respectively). Eighty\u2010two patients (30.1%) reported itching and painful skin within the past week. Using multivariate ordinal logistic regression models, it was found that an affected BSA of more than 25% was associated with self\u2010consciousness, difficulty with friendships and schoolwork, and teasing and bullying. Lesions on the face and arms were associated with teasing and bullying. The extent of vitiligo is associated with <jats:styled-content style=\"fixed-case\">QOL<\/jats:styled-content> impairment in children and adolescents, especially self\u2010consciousness, but also bullying and teasing. Different distributions of vitiligo lesions are associated with different aspects of <jats:styled-content style=\"fixed-case\">QOL<\/jats:styled-content> impairment. Teenagers ages 15 to 17 years seem to experience the most self\u2010consciousness of all pediatric age groups.<\/jats:p>","DOI":"10.1111\/pde.12226","type":"journal-article","created":{"date-parts":[[2013,10,18]],"date-time":"2013-10-18T04:56:38Z","timestamp":1382072198000},"page":"309-318","source":"Crossref","is-referenced-by-count":79,"title":["Quality of Life Impairment in Children and Adolescents with Vitiligo"],"prefix":"10.1111","volume":"31","author":[{"given":"Jonathan I.","family":"Silverberg","sequence":"first","affiliation":[{"name":"Department of Dermatology St. Luke's\u2010Roosevelt Hospital and Beth Israel Medical Centers New York New York"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nanette B.","family":"Silverberg","sequence":"additional","affiliation":[{"name":"Department of Dermatology St. Luke's\u2010Roosevelt Hospital and Beth Israel Medical Centers New York New York"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2013,10,18]]},"reference":[{"key":"e_1_2_5_2_1","first-page":"632","article-title":"Psychiatric morbidity and quality of life in vitiligo: a case controlled study","volume":"84","author":"Mechri A","year":"2006","journal-title":"Tunis Med"},{"key":"e_1_2_5_3_1","doi-asserted-by":"publisher","DOI":"10.1159\/000084751"},{"key":"e_1_2_5_4_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2133.2005.06456.x"},{"key":"e_1_2_5_5_1","doi-asserted-by":"publisher","DOI":"10.2298\/MPNS0606265P"},{"key":"e_1_2_5_6_1","doi-asserted-by":"publisher","DOI":"10.1590\/S0365-05962012000500004"},{"key":"e_1_2_5_7_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-4632.2012.05616.x"},{"key":"e_1_2_5_8_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2230.2010.03965.x"},{"key":"e_1_2_5_9_1","doi-asserted-by":"publisher","DOI":"10.1001\/jamadermatol.2013.927"},{"key":"e_1_2_5_10_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2133.1995.tb16953.x"},{"key":"e_1_2_5_11_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.0022-202X.2005.23621.x"},{"key":"e_1_2_5_12_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.2517-6161.1995.tb02031.x"},{"key":"e_1_2_5_13_1","first-page":"337","article-title":"Contributions of Erik Erikson","volume":"84","author":"Eagle M","year":"1997","journal-title":"Psychoanal Rev"},{"key":"e_1_2_5_14_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2133.2012.10922.x"},{"key":"e_1_2_5_15_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2133.2012.10996.x"},{"key":"e_1_2_5_16_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2133.2010.09993.x"},{"key":"e_1_2_5_17_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1346-8138.2011.01295.x"},{"key":"e_1_2_5_18_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1468-3083.2009.03452.x"},{"key":"e_1_2_5_19_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0190-9622(00)90133-6"}],"container-title":["Pediatric Dermatology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fpde.12226","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/pde.12226","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,29]],"date-time":"2023-09-29T19:30:53Z","timestamp":1696015853000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/pde.12226"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2013,10,18]]},"references-count":18,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2014,5]]}},"alternative-id":["10.1111\/pde.12226"],"URL":"https:\/\/doi.org\/10.1111\/pde.12226","archive":["Portico"],"relation":{},"ISSN":["0736-8046","1525-1470"],"issn-type":[{"value":"0736-8046","type":"print"},{"value":"1525-1470","type":"electronic"}],"subject":[],"published":{"date-parts":[[2013,10,18]]}}}