{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,30]],"date-time":"2026-09-30T09:32:17Z","timestamp":1790760737723,"version":"4.1.0"},"reference-count":24,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2014,1,29]],"date-time":"2014-01-29T00:00:00Z","timestamp":1390953600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Pediatric Dermatology"],"published-print":{"date-parts":[[2014,5]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Atopic eczema (<jats:styled-content style=\"fixed-case\">AE<\/jats:styled-content>) is the most common childhood inflammatory skin condition. The aim of this study was to evaluate the prevalence of <jats:styled-content style=\"fixed-case\">AE<\/jats:styled-content> and its relation to various risk factors. In a cross\u2010sectional study, 9,991 children ages 13 to 14 years in 61 primary schools in 32 districts of <jats:styled-content style=\"fixed-case\">I<\/jats:styled-content>stanbul were evaluated. The prevalence of <jats:styled-content style=\"fixed-case\">AE<\/jats:styled-content> and associated symptoms was assessed using the <jats:styled-content style=\"fixed-case\">I<\/jats:styled-content>nternational <jats:styled-content style=\"fixed-case\">S<\/jats:styled-content>tudy of <jats:styled-content style=\"fixed-case\">A<\/jats:styled-content>sthma and <jats:styled-content style=\"fixed-case\">A<\/jats:styled-content>llergies in <jats:styled-content style=\"fixed-case\">C<\/jats:styled-content>hildhood protocol. The relationship between risk factors and <jats:styled-content style=\"fixed-case\">AE<\/jats:styled-content> was evaluated using multivariate logistic regression analysis. Ten thousand nine hundred eighty\u2010four questionnaires were distributed to 13\u2010 and 14\u2010year\u2010old children in 61 schools in 32 districts of <jats:styled-content style=\"fixed-case\">I<\/jats:styled-content>stanbul, 9,991 of which were suitable for analysis, for an overall response rate of 91.7%. There were 4,746 boys (47.9%) and 5,166 girls (52.1%) (<jats:styled-content style=\"fixed-case\">M<\/jats:styled-content>\/<jats:styled-content style=\"fixed-case\">F<\/jats:styled-content> ratio 0.920). The rates of itchy rash ever, 12\u2010month itchy rash, and doctor\u2010diagnosed <jats:styled-content style=\"fixed-case\">AE<\/jats:styled-content> ever were 18.2%, 12.0%, and 2.8%, respectively. The difference between rates for itchy rash ever, 12\u2010month itchy rash and doctor\u2010diagnosed <jats:styled-content style=\"fixed-case\">AE<\/jats:styled-content> was high (12.8\u201331.3, 5.8\u201324.8, and 0\u201317.2, respectively) between the districts of <jats:styled-content style=\"fixed-case\">I<\/jats:styled-content>stanbul. Female sex, <jats:styled-content style=\"fixed-case\">AE<\/jats:styled-content> family history, watching television more than 5\u00a0hours a day, region of the district, and tonsillectomy history were found to be significantly associated with doctor\u2010diagnosed <jats:styled-content style=\"fixed-case\">AE<\/jats:styled-content> at p\u00a0&lt;\u00a00.05 in multivariate analysis. This study found a low prevalence of doctor\u2010diagnosed <jats:styled-content style=\"fixed-case\">AE<\/jats:styled-content> and related symptoms in <jats:styled-content style=\"fixed-case\">I<\/jats:styled-content>stanbul. Several risk factors were found to be associated with doctor\u2010diagnosed <jats:styled-content style=\"fixed-case\">AE<\/jats:styled-content>.<\/jats:p>","DOI":"10.1111\/pde.12244","type":"journal-article","created":{"date-parts":[[2014,1,30]],"date-time":"2014-01-30T06:25:03Z","timestamp":1391063103000},"page":"319-325","source":"Crossref","is-referenced-by-count":3,"title":["Prevalence and Risk Factors of Atopic Eczema in Turkish Adolescents"],"prefix":"10.1111","volume":"31","author":[{"given":"Ahmet","family":"Akcay","sequence":"first","affiliation":[{"name":"Division of Pediatric Allergy Department of Pediatrics Liv Hospital Istanbul Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zeynep","family":"Tamay","sequence":"additional","affiliation":[{"name":"Division of Pediatric Allergy Department of Pediatrics School of Medicine Istanbul University Istanbul Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ahmet","family":"Ergin","sequence":"additional","affiliation":[{"name":"Department of Pediatrics School of Medicine Pamukkale University Denizli Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nermin","family":"Guler","sequence":"additional","affiliation":[{"name":"Division of Pediatric Allergy Department of Pediatrics School of Medicine Istanbul University Istanbul Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2014,1,29]]},"reference":[{"key":"e_1_2_5_2_1","doi-asserted-by":"publisher","DOI":"10.1183\/09031936.95.08030483"},{"key":"e_1_2_5_3_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1365-2222.1998.028s5052.x"},{"key":"e_1_2_5_4_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2230.2012.04336.x"},{"key":"e_1_2_5_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0091-6749(99)70536-1"},{"key":"e_1_2_5_6_1","first-page":"81","article-title":"Denizli'deki 13\u201314 ya\u015f okul \u00e7ocuklar\u0131nda alerjik hastal\u0131k belirtilerinin yayg\u0131nl\u0131\u011f\u0131","volume":"41","author":"Akcay A","year":"2006","journal-title":"Turk Arch Pediatr"},{"key":"e_1_2_5_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0091-6749(00)91361-7"},{"key":"e_1_2_5_8_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1399-3038.2006.00464.x"},{"key":"e_1_2_5_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0301-0546(08)75866-X"},{"key":"e_1_2_5_10_1","first-page":"367","article-title":"Prevalence of atopic eczema and related symptoms in Brazilian schoolchildren: results from the International Study of Asthma and Allergies in Childhood (ISAAC) phase 3","volume":"16","author":"Sol\u00e9 D","year":"2006","journal-title":"J Investig Allergol Clin Immunol"},{"key":"e_1_2_5_11_1","first-page":"311","article-title":"Latin American ISAAC Phase 3 Study Group. 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