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Diapered skin is exposed to friction and excessive hydration, has a higher <jats:styled-content style=\"fixed-case\">pH<\/jats:styled-content> than nondiapered skin, and is repeatedly soiled with feces that contains enzymes with high irritation potential for the skin. The combination of these factors frequently results in skin damage, leading to visible erythematous lesions that can be irritating and painful to the child. Behavioral changes such as increased crying and agitation and changes in eating and sleeping patterns indicate emotional distress. Appropriate skin care can help to prevent the occurrence of <jats:styled-content style=\"fixed-case\">DD<\/jats:styled-content> and to speed up the healing of affected skin. This includes frequent diaper changes and aeration, gentle cleansing, and the use of a barrier cream. Mild to moderate cases usually resolve after a few days of following this routine, but the use of harsh cleaning products can exacerbate <jats:styled-content style=\"fixed-case\">DD<\/jats:styled-content>.<\/jats:p>","DOI":"10.1111\/pde.12245","type":"journal-article","created":{"date-parts":[[2013,11,14]],"date-time":"2013-11-14T07:22:47Z","timestamp":1384413767000},"page":"1-7","source":"Crossref","is-referenced-by-count":110,"title":["Diaper Dermatitis: Etiology, Manifestations, Prevention, and Management"],"prefix":"10.1111","volume":"31","author":[{"given":"Georgios N.","family":"Stamatas","sequence":"first","affiliation":[{"name":"Johnson &amp; Johnson Sant\u00e9 Beaut\u00e9 France Issy les Moulineaux France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Neena K.","family":"Tierney","sequence":"additional","affiliation":[{"name":"Johnson &amp; Johnson Consumer Companies Inc. 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