{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,11]],"date-time":"2026-05-11T11:28:19Z","timestamp":1778498899333,"version":"3.51.4"},"reference-count":20,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2013,11,14]],"date-time":"2013-11-14T00:00:00Z","timestamp":1384387200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Pediatric Dermatology"],"published-print":{"date-parts":[[2014,5]]},"abstract":"Abstract<\/jats:title>Nevus sebaceus (NS<\/jats:styled-content>) is a common congenital cutaneous hamartoma that typically presents on the scalp and face at birth or in early childhood. Occasionally NS<\/jats:styled-content> can be associated with the Schimmelpenning\u2013Feuerstein\u2013Mims syndrome, which presents with concomitant severe neurologic, skeletal, cardiovascular, ophthalmic, and genitourologic disorders. In a previous study, maternal transmission of the human papillomavirus (HPV<\/jats:styled-content>) and infection of ectodermal stem cells by HPV<\/jats:styled-content> was postulated to result in the development of NS<\/jats:styled-content>. In this study we aimed to determine the incidence of HPV<\/jats:styled-content> infection in pediatric NS<\/jats:styled-content> samples to further clarify the potential link between HPV<\/jats:styled-content> and the pathogenesis of NS<\/jats:styled-content>. NS<\/jats:styled-content> tissue samples (N<\/jats:italic>\u00a0=\u00a016) were analyzed for HPV DNA<\/jats:styled-content> using type\u2010specific, real\u2010time polymerase chain reaction (PCR<\/jats:styled-content>) targeting HPV<\/jats:styled-content> 6, 11, 16, and 18 and conventional PCR<\/jats:styled-content> with modified general primers designed for broad\u2010range HPV<\/jats:styled-content> detection. The tissues were also histologically evaluated for evidence of HPV<\/jats:styled-content> infection. HPV DNA<\/jats:styled-content> was not detected in any of the NS<\/jats:styled-content> tissue samples using PCR<\/jats:styled-content> and HPV<\/jats:styled-content>\u2010associated histopathologic changes were absent in all 16 NS<\/jats:styled-content> tissues. HPV<\/jats:styled-content> infection is an unlikely etiologic cause of NS<\/jats:styled-content>.<\/jats:p>","DOI":"10.1111\/pde.12249","type":"journal-article","created":{"date-parts":[[2013,11,14]],"date-time":"2013-11-14T07:24:39Z","timestamp":1384413879000},"page":"326-330","source":"Crossref","is-referenced-by-count":3,"title":["Human Papilloma Virus is not Prevalent in Nevus Sebaceus"],"prefix":"10.1111","volume":"31","author":[{"given":"David","family":"Kim","sequence":"first","affiliation":[{"name":"Department of Dermatology Stanford University School of Medicine Stanford California"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Latanya T.","family":"Benjamin","sequence":"additional","affiliation":[{"name":"Department of Dermatology Stanford University School of Medicine Stanford California"},{"name":"Department of Pediatrics Stanford University School of Medicine Stanford California"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Malaya K.","family":"Sahoo","sequence":"additional","affiliation":[{"name":"Department of Pathology Stanford University School of Medicine Stanford California"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jinah","family":"Kim","sequence":"additional","affiliation":[{"name":"Department of Dermatology Stanford University School of Medicine Stanford California"},{"name":"Department of Pathology Stanford University School of Medicine Stanford California"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Benjamin A.","family":"Pinsky","sequence":"additional","affiliation":[{"name":"Department of Pathology Stanford University School of Medicine Stanford California"},{"name":"Division of Infectious Diseases and Geographic Medicine Department of Medicine Stanford University School of Medicine Stanford California"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2013,11,14]]},"reference":[{"key":"e_1_2_5_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaad.2009.04.058"},{"key":"e_1_2_5_3_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1525-1470.2011.01562.x"},{"key":"e_1_2_5_4_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1524-4725.2010.01746.x"},{"key":"e_1_2_5_5_1","doi-asserted-by":"publisher","DOI":"10.1001\/archderm.1965.01600120006002"},{"key":"e_1_2_5_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0190-9622(00)90136-1"},{"key":"e_1_2_5_7_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1525-1470.2009.00939.x"},{"key":"e_1_2_5_8_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1525-1470.1993.tb00053.x"},{"key":"e_1_2_5_9_1","doi-asserted-by":"publisher","DOI":"10.1001\/archderm.135.6.637"},{"key":"e_1_2_5_10_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1524-4725.2010.01611.x"},{"key":"e_1_2_5_11_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaad.2009.04.059"},{"key":"e_1_2_5_12_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.pediatrneurol.2007.10.012"},{"key":"e_1_2_5_13_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaad.2008.03.020"},{"key":"e_1_2_5_14_1","doi-asserted-by":"publisher","DOI":"10.1128\/JCM.02007-08"},{"key":"e_1_2_5_15_1","doi-asserted-by":"publisher","DOI":"10.5858\/arpa.2011-0392-OA"},{"key":"e_1_2_5_16_1","first-page":"379","article-title":"Condylomatous lesions of the cervix. 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