{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,4]],"date-time":"2026-08-04T23:55:15Z","timestamp":1785887715451,"version":"3.56.0"},"reference-count":13,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2014,1,24]],"date-time":"2014-01-24T00:00:00Z","timestamp":1390521600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Pediatric Dermatology"],"published-print":{"date-parts":[[2014,3]]},"abstract":"Abstract<\/jats:title>Xeroderma pigmentosum (XP<\/jats:styled-content>) is a rare autosomal recessive disorder characterized by clinical and cellular sensitivity, pigmentary changes, and early development of malignancies in sun\u2010exposed mucocutaneous and ocular structures due to a defective ability to repair intracellular DNA<\/jats:styled-content> damage. Individuals with XP<\/jats:styled-content> also have a greater frequency of oral cancer, particularly squamous cell carcinoma of the anterior third of the tongue. The current study reports four cases of XP<\/jats:styled-content> that exhibited a characteristic crescent\u2010shaped, atrophic, telangiectatic area on the distal border of the tongue and correlates this lesion with the development of tumors at this site during follow\u2010up. The tongue lesion was photographed and biopsied in the four patients. During routine follow\u2010up visits, new biopsies were performed if additional tongue lesions were observed. The studied lesions were similar in the four patients. During follow\u2010up, squamous cell carcinoma developed in one patient and pyogenic granuloma developed in three patients and was relapsing in one. The lesion remained stable in one patient during the study. The atrophic and telangiectatic patches probably occur because of chronic sun damage to the exposed portion of the tongue, and this area has a high predisposition for the development of benign and malignant tumors.<\/jats:p>","DOI":"10.1111\/pde.12272","type":"journal-article","created":{"date-parts":[[2014,1,24]],"date-time":"2014-01-24T08:35:37Z","timestamp":1390552537000},"source":"Crossref","is-referenced-by-count":12,"title":["An Atrophic, Telangiectatic Patch at the Distal Border of the Tongue: A Mucous Membrane Manifestation of Xeroderma Pigmentosum"],"prefix":"10.1111","volume":"31","author":[{"given":"Sheyla Batista","family":"Bologna","sequence":"first","affiliation":[{"name":"Department of Dermatology School of Medicine University of S\u00e3o Paulo S\u00e3o Paulo Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tathyane","family":"Harumi Nakajima Teshima","sequence":"additional","affiliation":[{"name":"Department of General Pathology School of Dentistry University of S\u00e3o Paulo S\u00e3o Paulo Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Silvia Vanessa","family":"Louren\u00e7o","sequence":"additional","affiliation":[{"name":"Department of Dermatology School of Medicine University of S\u00e3o Paulo S\u00e3o Paulo Brazil"},{"name":"Department of General Pathology School of Dentistry University of S\u00e3o Paulo S\u00e3o Paulo Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marcello Menta Simonsen","family":"Nico","sequence":"additional","affiliation":[{"name":"Department of Dermatology School of Medicine University of S\u00e3o Paulo S\u00e3o Paulo Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2014,1,24]]},"reference":[{"key":"e_1_2_5_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcms.2010.02.006"},{"key":"e_1_2_5_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.joms.2007.09.026"},{"key":"e_1_2_5_4_1","doi-asserted-by":"publisher","DOI":"10.1186\/1750-1172-6-70"},{"key":"e_1_2_5_5_1","doi-asserted-by":"publisher","DOI":"10.1038\/jid.2011.426"},{"key":"e_1_2_5_6_1","doi-asserted-by":"publisher","DOI":"10.1034\/j.1600-0625.2003.00124.x"},{"key":"e_1_2_5_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/0738-081X(85)90096-3"},{"key":"e_1_2_5_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/0030-4220(91)90303-T"},{"key":"e_1_2_5_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaad.2008.06.030"},{"key":"e_1_2_5_10_1","volume-title":"Atlas of clinical oncology: cancer of the head and neck","author":"Shah JP","year":"2001"},{"key":"e_1_2_5_11_1","doi-asserted-by":"publisher","DOI":"10.1007\/s12105-011-0303-x"},{"key":"e_1_2_5_12_1","doi-asserted-by":"publisher","DOI":"10.1016\/0190-9622(92)70010-D"},{"key":"e_1_2_5_13_1","first-page":"530","article-title":"Xeroderma pigmentosum: squamous cell carcinoma of the tongue","volume":"69","author":"Keukens F","year":"1989","journal-title":"Acta Derm Venereol"},{"key":"e_1_2_5_14_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0300-9785(81)80011-7"}],"container-title":["Pediatric Dermatology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fpde.12272","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/pde.12272","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,23]],"date-time":"2023-09-23T13:09:52Z","timestamp":1695474592000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/pde.12272"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2014,1,24]]},"references-count":13,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2014,3]]}},"alternative-id":["10.1111\/pde.12272"],"URL":"https:\/\/doi.org\/10.1111\/pde.12272","archive":["Portico"],"relation":{},"ISSN":["0736-8046","1525-1470"],"issn-type":[{"value":"0736-8046","type":"print"},{"value":"1525-1470","type":"electronic"}],"subject":[],"published":{"date-parts":[[2014,1,24]]}}}