{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,18]],"date-time":"2026-08-18T01:19:12Z","timestamp":1787015952988,"version":"build-2736575974"},"reference-count":43,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2014,5,29]],"date-time":"2014-05-29T00:00:00Z","timestamp":1401321600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"name":"This project was supported by Johnson & Johnson","award":["Johnson& Johnson"],"award-info":[{"award-number":["Johnson& Johnson"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Pediatric Dermatology"],"published-print":{"date-parts":[[2014,7]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>\n                    Diaper dermatitis (\n                    <jats:styled-content style=\"fixed-case\">DD<\/jats:styled-content>\n                    ) is one of the most common skin conditions in neonates and infants, with a peak between the ages of 9 and 12\u00a0months. Appropriate skin care practices that support skin barrier function and protect the buttocks skin from urine and feces are supposed to be effective in the prevention of\n                    <jats:styled-content style=\"fixed-case\">DD<\/jats:styled-content>\n                    . Despite many recommendations for parents and caregivers on proper diaper skin care, there is no up\u2010to\u2010date synthesis of the available evidence to develop recommendations for\n                    <jats:styled-content style=\"fixed-case\">DD<\/jats:styled-content>\n                    prevention practice. Therefore we performed a systematic literature review on the efficacy of nonmedical skin care practices on the diapered area of healthy, full\u2010term infants ages 0 to 24\u00a0months. We identified 13 studies covering skin care practices such as cleansing, bathing, and application of topical products.\n                    <jats:styled-content style=\"fixed-case\">DD<\/jats:styled-content>\n                    prevalence and incidence and physiologic skin parameters were used as efficacy parameters. The results of this review indicate that cleansing of the diaper area using baby wipes or water and a washcloth have comparable effects on diapered skin. Bathing with a liquid baby cleanser twice weekly seems comparable with water alone. The application of ointments containing zinc oxide or petrolatum with or without vitamin A seems to have comparable effects on\n                    <jats:styled-content style=\"fixed-case\">DD<\/jats:styled-content>\n                    severity. There seems to be no information on whether single skin care practices such as cleansing, bathing, and application of topical preparations can prevent\n                    <jats:styled-content style=\"fixed-case\">DD<\/jats:styled-content>\n                    . High\u2010quality randomized clinical trials are needed to show the effectiveness of skin care practices for controlling and preventing\n                    <jats:styled-content style=\"fixed-case\">DD<\/jats:styled-content>\n                    .\n                  <\/jats:p>","DOI":"10.1111\/pde.12348","type":"journal-article","created":{"date-parts":[[2014,5,29]],"date-time":"2014-05-29T04:56:59Z","timestamp":1401339419000},"page":"413-429","source":"Crossref","is-referenced-by-count":73,"title":["Prevention of Diaper Dermatitis in Infants\u2014a Literature Review"],"prefix":"10.1111","volume":"31","author":[{"given":"Ulrike","family":"Blume\u2010Peytavi","sequence":"first","affiliation":[{"name":"Department of Dermatology and Allergy Clinical Research Center for Hair and Skin Science Charit\u00e9\u2014Universit\u00e4tsmedizin Berlin Berlin Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Matthias","family":"Hauser","sequence":"additional","affiliation":[{"name":"Johnson &amp; Johnson GmbH Neuss Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lena","family":"L\u00fcnnemann","sequence":"additional","affiliation":[{"name":"Department of Dermatology and Allergy Clinical Research Center for Hair and Skin Science Charit\u00e9\u2014Universit\u00e4tsmedizin Berlin Berlin Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Georgios N.","family":"Stamatas","sequence":"additional","affiliation":[{"name":"Johnson &amp; Johnson Sant\u00e9 Beaut\u00e9 France Issy\u2010les\u2010Moulineaux France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jan","family":"Kottner","sequence":"additional","affiliation":[{"name":"Department of Dermatology and Allergy Clinical Research Center for Hair and Skin Science Charit\u00e9\u2014Universit\u00e4tsmedizin Berlin Berlin Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Natalie","family":"Garcia Bartels","sequence":"additional","affiliation":[{"name":"Department of Dermatology and Allergy Clinical Research Center for Hair and Skin Science Charit\u00e9\u2014Universit\u00e4tsmedizin Berlin Berlin Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2014,5,29]]},"reference":[{"key":"e_1_2_5_2_1","first-page":"75","article-title":"Etiology and pathophysiology of diaper dermatitis","volume":"3","author":"Berg RW","year":"1988","journal-title":"Adv Dermatol"},{"key":"e_1_2_5_3_1","doi-asserted-by":"publisher","DOI":"10.1007\/3-540-31294-3_5"},{"key":"e_1_2_5_4_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1525-1470.1986.tb00513.x"},{"key":"e_1_2_5_5_1","first-page":"493","article-title":"Getting to the bottom of nappy rash: ALSPAC survey team. 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