{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,3]],"date-time":"2026-09-03T00:55:44Z","timestamp":1788396944898,"version":"build-2803163510"},"reference-count":25,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2014,5,29]],"date-time":"2014-05-29T00:00:00Z","timestamp":1401321600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Pediatric Dermatology"],"published-print":{"date-parts":[[2014,7]]},"abstract":"Abstract<\/jats:title>Few studies have evaluated Asian children with mycosis fungoides (MF<\/jats:styled-content>). We report a series of patients from a tertiary dermatologic institution in S<\/jats:styled-content>ingapore. A retrospective review was performed of patients younger than 16\u00a0years old diagnosed with MF<\/jats:styled-content> between 2000 and 2008 at the N<\/jats:styled-content>ational S<\/jats:styled-content>kin C<\/jats:styled-content>entre, S<\/jats:styled-content>ingapore. Forty\u2010six patients were identified. At initial presentation, a provisional diagnosis of MF<\/jats:styled-content> was made in 19 patients (41.3%), pityriasis lichenoides chronica (PLC<\/jats:styled-content>) in 11 (23.9%) and postinflammatory hypopigmentation due to eczema or other causes in 11 (23.9%). After skin biopsy, the hypopigmented variant of MF<\/jats:styled-content> was diagnosed in 42 patients (91.3%). There was one case each of PLC<\/jats:styled-content>\u2010like MF<\/jats:styled-content>, pigmented purpuric dermatosis\u2010like MF<\/jats:styled-content>, classic MF<\/jats:styled-content>, and solitary MF<\/jats:styled-content>. Pityriasis lichenoides coexisted in three cases (6.5%). All except one patient presented with the early patch\u2010plaque stage of disease (stage IA<\/jats:styled-content>\/B<\/jats:styled-content>). The disease did not progress in any of our patients after a mean follow\u2010up of 71.0\u00a0\u00b1\u00a052.5\u00a0months. Twenty\u2010seven patients (58.7%) had complete disease clearance after a mean duration of 27.1\u00a0\u00b1\u00a028.1\u00a0months; 15 (49.7%) of 32 patients who received narrowband ultraviolet B treatment had complete clearance within an average of 8.9\u00a0\u00b1\u00a05.3\u00a0months, but 7 patients relapsed within 14.9\u00a0\u00b1\u00a014.8\u00a0months. One patient with solitary MF<\/jats:styled-content> failed multiple treatment modalities before eventually achieving disease clearance with photodynamic therapy. Hypopigmented MF<\/jats:styled-content> is the most common MF<\/jats:styled-content> variant in Asian children. The diagnostic difficulty is in differentiating this from PLC<\/jats:styled-content>, which may coexist with MF<\/jats:styled-content>. Long\u2010term prognosis is generally favorable.<\/jats:p>","DOI":"10.1111\/pde.12352","type":"journal-article","created":{"date-parts":[[2014,5,29]],"date-time":"2014-05-29T10:11:58Z","timestamp":1401358318000},"page":"477-482","source":"Crossref","is-referenced-by-count":54,"title":["Pediatric Mycosis Fungoides in Singapore: A Series of 46 Children"],"prefix":"10.1111","volume":"31","author":[{"given":"Yee Kiat","family":"Heng","sequence":"first","affiliation":[{"name":"National Skin Centre Singapore Singapore"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mark Jean Aan","family":"Koh","sequence":"additional","affiliation":[{"name":"National Skin Centre Singapore Singapore"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yoke Chin","family":"Giam","sequence":"additional","affiliation":[{"name":"National Skin Centre Singapore Singapore"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mark Boon Yang","family":"Tang","sequence":"additional","affiliation":[{"name":"National Skin Centre Singapore Singapore"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wei Sheng","family":"Chong","sequence":"additional","affiliation":[{"name":"National Skin Centre Singapore Singapore"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Suat Hoon","family":"Tan","sequence":"additional","affiliation":[{"name":"National Skin Centre Singapore Singapore"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2014,5,29]]},"reference":[{"key":"e_1_2_5_2_1","doi-asserted-by":"publisher","DOI":"10.1002\/cncr.11780"},{"key":"e_1_2_5_3_1","doi-asserted-by":"publisher","DOI":"10.2310\/7750.2009.08091"},{"key":"e_1_2_5_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0190-9622(97)70243-3"},{"key":"e_1_2_5_5_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1346-8138.2009.00665.x"},{"key":"e_1_2_5_6_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1525-1470.2000.017005352.x"},{"key":"e_1_2_5_7_1","doi-asserted-by":"publisher","DOI":"10.1080\/00015550310020530"},{"key":"e_1_2_5_8_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1525-1470.2010.01129.x"},{"key":"e_1_2_5_9_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1468-3083.2011.04383.x"},{"key":"e_1_2_5_10_1","doi-asserted-by":"publisher","DOI":"10.1182\/blood-2007-03-055749"},{"key":"e_1_2_5_11_1","doi-asserted-by":"publisher","DOI":"10.1001\/archderm.143.7.854"},{"key":"e_1_2_5_12_1","doi-asserted-by":"publisher","DOI":"10.1067\/S0190-9622(03)00907-1"},{"key":"e_1_2_5_13_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1440-0960.2006.00290.x"},{"key":"e_1_2_5_14_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1365-2133.2000.03307.x"},{"key":"e_1_2_5_15_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaad.2005.08.057"},{"key":"e_1_2_5_16_1","doi-asserted-by":"publisher","DOI":"10.1001\/archderm.139.7.857"},{"key":"e_1_2_5_17_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0781.2011.00559.x"},{"key":"e_1_2_5_18_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0781.2004.00084.x"},{"key":"e_1_2_5_19_1","first-page":"2212","article-title":"Transformation of mycosis fungoides: clinicopathological and prognostic features of 45 cases. 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