{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,28]],"date-time":"2026-01-28T06:43:53Z","timestamp":1769582633774,"version":"3.49.0"},"reference-count":17,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2014,9,10]],"date-time":"2014-09-10T00:00:00Z","timestamp":1410307200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Pediatric Dermatology"],"published-print":{"date-parts":[[2014,11]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Diaper dermatitis, a common skin problem in newborn infants, is characterized by poor functioning of the skin barrier. This study aimed to elucidate the relationship between skin barrier function in 4\u2010day\u2010old infants and the occurrence of diaper dermatitis during the first month of life. We recruited healthy <jats:styled-content style=\"fixed-case\">J<\/jats:styled-content>apanese infants born at 35\u00a0weeks of gestation or more. We measured indicators of skin barrier function, namely skin p<jats:styled-content style=\"fixed-case\">H<\/jats:styled-content> and transepidermal water loss, in 4\u2010day\u2010old infants on four places on the body. Individual characteristics were recorded from the infants' medical charts. The presence of diaper dermatitis was judged using the diaper rash and erythema scoring scale, which was based on daily recording of the infants' skin condition by their parents. The parents also filled out a questionnaire 1\u00a0month after birth regarding stool frequency and certain external factors. The association between diaper dermatitis and skin barrier function was assessed using multiple logistic regression analysis. The analysis included 88 infants. The incidence of diaper dermatitis was 25.0%. After adjusting for stool frequency for 1\u00a0month we noted that high p<jats:styled-content style=\"fixed-case\">H<\/jats:styled-content> on the inner arm skin in 4\u2010day\u2010old infants increased the risk of diaper dermatitis during the first month of life (adjusted odds ratio 3.35 [95% confidence interval\u00a0=\u00a01.12, 10.04]). Early neonatal skin p<jats:styled-content style=\"fixed-case\">H<\/jats:styled-content> may predict the risk of diaper dermatitis during the first month of life. Our results may be useful in devising strategies to prevent diaper dermatitis.<\/jats:p>","DOI":"10.1111\/pde.12394","type":"journal-article","created":{"date-parts":[[2014,9,11]],"date-time":"2014-09-11T01:33:03Z","timestamp":1410399183000},"page":"692-697","source":"Crossref","is-referenced-by-count":20,"title":["Relationship Between Skin Barrier Function in Early Neonates and Diaper Dermatitis During the First Month of Life: A Prospective Observational Study"],"prefix":"10.1111","volume":"31","author":[{"given":"Kaori","family":"Yonezawa","sequence":"first","affiliation":[{"name":"Department of Midwifery and Women's Health Division of Health Sciences and Nursing Graduate School of Medicine University of Tokyo Tokyo Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Megumi","family":"Haruna","sequence":"additional","affiliation":[{"name":"Department of Midwifery and Women's Health Division of Health Sciences and Nursing Graduate School of Medicine University of Tokyo Tokyo Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mie","family":"Shiraishi","sequence":"additional","affiliation":[{"name":"Department of Midwifery and Women's Health Division of Health Sciences and Nursing Graduate School of Medicine University of Tokyo Tokyo Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Masayo","family":"Matsuzaki","sequence":"additional","affiliation":[{"name":"Department of Midwifery and Women's Health Division of Health Sciences and Nursing Graduate School of Medicine University of Tokyo Tokyo Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hiromi","family":"Sanada","sequence":"additional","affiliation":[{"name":"Department of Gerontological Nursing and Wound Care Management Division of Health Sciences and Nursing Graduate School of Medicine University of Tokyo Tokyo Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2014,9,10]]},"reference":[{"key":"e_1_2_6_2_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1525-1470.2000.01710.x"},{"key":"e_1_2_6_3_1","first-page":"493","article-title":"Getting to the bottom of nappy rash. 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Avon Longitudinal Study of Pregnancy and Childhood","volume":"47","author":"Philipp R","year":"1997","journal-title":"Br J Gen Pract"},{"key":"e_1_2_6_4_1","first-page":"1","article-title":"Practical management strategies for diaper dermatitis","volume":"11","author":"Humphrey S","year":"2006","journal-title":"Skin Therapy Lett"},{"key":"e_1_2_6_5_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1525-1470.2007.00499.x"},{"key":"e_1_2_6_6_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1525-1470.2011.01308.x"},{"key":"e_1_2_6_7_1","doi-asserted-by":"publisher","DOI":"10.1159\/000076015"},{"key":"e_1_2_6_8_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1525-1470.1994.tb00066.x"},{"key":"e_1_2_6_9_1","doi-asserted-by":"publisher","DOI":"10.1159\/000018366"},{"key":"e_1_2_6_10_1","doi-asserted-by":"publisher","DOI":"10.1542\/peds.106.1.105"},{"key":"e_1_2_6_11_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1525-1470.2000.01711.x"},{"key":"e_1_2_6_12_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1525-1470.2011.01594.x"},{"key":"e_1_2_6_13_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1525-1470.2002.00082.x"},{"key":"e_1_2_6_14_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1525-1470.2009.01068.x"},{"key":"e_1_2_6_15_1","first-page":"1147","article-title":"Functional analysis of the stratum corneum in newborns","volume":"117","author":"Shirasaka M","year":"2007","journal-title":"Jpn J Dermatol"},{"key":"e_1_2_6_16_1","doi-asserted-by":"publisher","DOI":"10.2165\/00128071-200203040-00004"},{"issue":"1","key":"e_1_2_6_17_1","first-page":"18","article-title":"Common conditions and factors associated with diaper dermatitis","volume":"14","author":"Hayakawa R","year":"1987","journal-title":"Pediatrician"},{"key":"e_1_2_6_18_1","first-page":"77","article-title":"Physiological properties of infants' skin","volume":"12","author":"Kawajiri Y","year":"1993","journal-title":"J Pediatr Dermatol"}],"container-title":["Pediatric Dermatology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fpde.12394","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/pde.12394","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,1]],"date-time":"2023-10-01T09:57:22Z","timestamp":1696154242000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/pde.12394"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2014,9,10]]},"references-count":17,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2014,11]]}},"alternative-id":["10.1111\/pde.12394"],"URL":"https:\/\/doi.org\/10.1111\/pde.12394","archive":["Portico"],"relation":{},"ISSN":["0736-8046","1525-1470"],"issn-type":[{"value":"0736-8046","type":"print"},{"value":"1525-1470","type":"electronic"}],"subject":[],"published":{"date-parts":[[2014,9,10]]}}}