{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,11]],"date-time":"2026-05-11T10:53:45Z","timestamp":1778496825403,"version":"3.51.4"},"reference-count":18,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2014,12,22]],"date-time":"2014-12-22T00:00:00Z","timestamp":1419206400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Pediatric Dermatology"],"published-print":{"date-parts":[[2015,3]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Areas of blanched skin in children may be seen as an independent finding or in association with vascular birthmarks. We performed a retrospective chart review to identify and describe infants with areas of ventral midline blanching in the presence of segmental infantile hemangiomas. We identified nine full\u2010term infants with partial or full segmental hemangiomas and areas of midline ventral blanching. Additional ventral wall defects were seen in five patients. Six had cardiac anomalies and six had intracranial anomalies. Five were diagnosed with definite <jats:styled-content style=\"fixed-case\">PHACE<\/jats:styled-content> (posterior fossa, hemangioma, arterial, cardiac, and eye abnormalities) syndrome and three had possible <jats:styled-content style=\"fixed-case\">PHACE<\/jats:styled-content> syndrome. Eight were complicated by ulceration. Treatment varied according to the case. Ventral blanching, even in the absence of overt midline defects, can be seen in infants with segmental hemangiomas at risk for <jats:styled-content style=\"fixed-case\">PHACE<\/jats:styled-content> syndrome. We hypothesize that midline blanching may represent a minor manifestation of a developmental ventral defect.<\/jats:p>","DOI":"10.1111\/pde.12462","type":"journal-article","created":{"date-parts":[[2014,12,22]],"date-time":"2014-12-22T10:17:13Z","timestamp":1419243433000},"page":"180-187","source":"Crossref","is-referenced-by-count":5,"title":["Ventral Midline Blanching in the Setting of Segmental Infantile Hemangiomas: Clinical Observations and Pathogenetic Implications"],"prefix":"10.1111","volume":"32","author":[{"given":"Dana F.","family":"Feigenbaum","sequence":"first","affiliation":[{"name":"School of Medicine University of California, San Diego San Diego California"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Virginia P.","family":"Sybert","sequence":"additional","affiliation":[{"name":"Division of Medical Genetics Department of Medicine University of Washington Seattle Washington"},{"name":"Department of Dermatology Group Health Physicians Seattle Washington"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sheryll L.","family":"Vanderhooft","sequence":"additional","affiliation":[{"name":"Department of Dermatology School of Medicine University of Utah Salt Lake City Utah"},{"name":"Department of Pediatrics School of Medicine University of Utah Salt Lake City Utah"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Dawn","family":"Siegel","sequence":"additional","affiliation":[{"name":"Department of Dermatology Medical College of Wisconsin Milwaukee Wisconsin"},{"name":"Department of Pediatrics Medical College of Wisconsin Milwaukee Wisconsin"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Beth A.","family":"Drolet","sequence":"additional","affiliation":[{"name":"Department of Dermatology Medical College of Wisconsin Milwaukee Wisconsin"},{"name":"Department of Pediatrics Medical College of Wisconsin Milwaukee Wisconsin"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ilona J.","family":"Frieden","sequence":"additional","affiliation":[{"name":"Department of Dermatology University of California at San Francisco San Francisco California"},{"name":"Department of Pediatrics University of California, San Francisco San Francisco California"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Erin F. D.","family":"Mathes","sequence":"additional","affiliation":[{"name":"Department of Dermatology University of California at San Francisco San Francisco California"},{"name":"Department of Pediatrics University of California, San Francisco San Francisco California"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2014,12,22]]},"reference":[{"key":"e_1_2_6_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaad.2013.09.018"},{"key":"e_1_2_6_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaad.2003.10.670"},{"key":"e_1_2_6_4_1","doi-asserted-by":"publisher","DOI":"10.3345\/kjp.2013.56.3.135"},{"key":"e_1_2_6_5_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM199907153410307"},{"key":"e_1_2_6_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0190-9622(86)70080-7"},{"key":"e_1_2_6_7_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2133.1996.tb07616.x"},{"key":"e_1_2_6_8_1","doi-asserted-by":"publisher","DOI":"10.1001\/jamadermatol.2013.6434"},{"key":"e_1_2_6_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaad.2013.06.039"},{"key":"e_1_2_6_10_1","doi-asserted-by":"publisher","DOI":"10.1001\/archdermatol.2010.197"},{"key":"e_1_2_6_11_1","doi-asserted-by":"publisher","DOI":"10.1089\/lrb.2007.1014"},{"key":"e_1_2_6_12_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10456-009-9148-2"},{"key":"e_1_2_6_13_1","doi-asserted-by":"publisher","DOI":"10.1001\/archdermatol.2010.1295"},{"key":"e_1_2_6_14_1","doi-asserted-by":"publisher","DOI":"10.1002\/ajmg.1320210127"},{"key":"e_1_2_6_15_1","doi-asserted-by":"publisher","DOI":"10.1002\/ajmg.1320420118"},{"key":"e_1_2_6_16_1","doi-asserted-by":"publisher","DOI":"10.1053\/jpsu.2003.50038"},{"issue":"3","key":"e_1_2_6_17_1","first-page":"365","article-title":"The development of the supra\u2010umbilical portion of the anterior abdominal wall","volume":"72","author":"Wyburn GM","year":"1938","journal-title":"J Anat"},{"key":"e_1_2_6_18_1","doi-asserted-by":"publisher","DOI":"10.1002\/ajmg.1320520203"},{"key":"e_1_2_6_19_1","doi-asserted-by":"publisher","DOI":"10.1053\/j.sempedsurg.2008.03.004"}],"container-title":["Pediatric Dermatology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fpde.12462","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/pde.12462","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,29]],"date-time":"2023-09-29T14:08:10Z","timestamp":1695996490000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/pde.12462"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2014,12,22]]},"references-count":18,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2015,3]]}},"alternative-id":["10.1111\/pde.12462"],"URL":"https:\/\/doi.org\/10.1111\/pde.12462","archive":["Portico"],"relation":{},"ISSN":["0736-8046","1525-1470"],"issn-type":[{"value":"0736-8046","type":"print"},{"value":"1525-1470","type":"electronic"}],"subject":[],"published":{"date-parts":[[2014,12,22]]}}}