{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,19]],"date-time":"2026-02-19T00:51:18Z","timestamp":1771462278573,"version":"3.50.1"},"reference-count":10,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2014,12,9]],"date-time":"2014-12-09T00:00:00Z","timestamp":1418083200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Pediatric Dermatology"],"published-print":{"date-parts":[[2015,1]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Pyrethroids are broad\u2010spectrum insecticides. Permethrin intoxication due to topical application has not been documented in humans. We report a 20\u2010month\u2010old infant who had used 5% permethrin lotion topically for scabies treatment. Approximately 60\u00a0mL (20\u00a0mL\/day) was used and after the third application he developed agitation, nausea, vomiting, respiratory distress, tachycardia, and metabolic acidosis. His clinical symptoms and metabolic acidosis normalized within 20\u00a0hours. His follow\u2010up was unremarkable. Toxicity of permethrin is rare, and although permethrin is a widely and safely used topical agent in the treatment of scabies and lice, inappropriate use may rarely cause toxicity. Moreover, in cases of unexplained metabolic acidosis, topically applied medications should be carefully investigated.<\/jats:p>","DOI":"10.1111\/pde.12473","type":"journal-article","created":{"date-parts":[[2014,12,9]],"date-time":"2014-12-09T15:16:46Z","timestamp":1418138206000},"source":"Crossref","is-referenced-by-count":16,"title":["Metabolic Acidosis in an Infant Associated with Permethrin Toxicity"],"prefix":"10.1111","volume":"32","author":[{"given":"Sevil B.","family":"Goksugur","sequence":"first","affiliation":[{"name":"Department of Pediatrics Medical Faculty Abant Izzet Baysal University Bolu Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Zehra","family":"Karatas","sequence":"additional","affiliation":[{"name":"Department of Pediatric Cardiology Medical Faculty Abant Izzet Baysal University Bolu Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nadir","family":"Goksugur","sequence":"additional","affiliation":[{"name":"Department of Dermatology Medical Faculty Abant Izzet Baysal University Bolu Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mervan","family":"Bekdas","sequence":"additional","affiliation":[{"name":"Department of Pediatrics Medical Faculty Abant Izzet Baysal University Bolu Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Fatih","family":"Demircioglu","sequence":"additional","affiliation":[{"name":"Department of Pediatrics Medical Faculty Abant Izzet Baysal University Bolu Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2014,12,9]]},"reference":[{"key":"e_1_2_4_2_1","doi-asserted-by":"publisher","DOI":"10.2165\/00139709-200524020-00003"},{"key":"e_1_2_4_3_1","volume-title":"Safety of Pyrethroid for\u00a0Public Health Use","author":"World Health Organization","year":"2005"},{"key":"e_1_2_4_4_1","first-page":"145","article-title":"Metabolic acidosis","volume":"39","author":"Lim S","year":"2007","journal-title":"Acta Med Indones"},{"key":"e_1_2_4_5_1","doi-asserted-by":"publisher","DOI":"10.1590\/S0021-75572007000300003"},{"key":"e_1_2_4_6_1","doi-asserted-by":"publisher","DOI":"10.3109\/15563659809162587"},{"key":"e_1_2_4_7_1","doi-asserted-by":"publisher","DOI":"10.1007\/s13181-010-0032-7"},{"key":"e_1_2_4_8_1","volume-title":"WHO Specifications and Evaluations for Public Health Pesticides","author":"Prallethrin","year":"2004"},{"key":"e_1_2_4_9_1","doi-asserted-by":"publisher","DOI":"10.1081\/CLT-100100922"},{"key":"e_1_2_4_10_1","doi-asserted-by":"publisher","DOI":"10.1081\/CLT-120004397"},{"key":"e_1_2_4_11_1","doi-asserted-by":"publisher","DOI":"10.1378\/chest.117.1.260"}],"container-title":["Pediatric Dermatology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fpde.12473","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/pde.12473","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,1]],"date-time":"2023-10-01T20:52:38Z","timestamp":1696193558000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/pde.12473"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2014,12,9]]},"references-count":10,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2015,1]]}},"alternative-id":["10.1111\/pde.12473"],"URL":"https:\/\/doi.org\/10.1111\/pde.12473","archive":["Portico"],"relation":{},"ISSN":["0736-8046","1525-1470"],"issn-type":[{"value":"0736-8046","type":"print"},{"value":"1525-1470","type":"electronic"}],"subject":[],"published":{"date-parts":[[2014,12,9]]}}}