{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,6]],"date-time":"2026-04-06T11:47:27Z","timestamp":1775476047277,"version":"3.50.1"},"reference-count":17,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2015,1,30]],"date-time":"2015-01-30T00:00:00Z","timestamp":1422576000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Pediatric Dermatology"],"published-print":{"date-parts":[[2015,3]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Vitiligo is a common acquired progressive depigmenting condition that can have devastating psychological effects in dark\u2010skinned patients. We performed a retrospective review of patients younger than 16 years of age with a clinical diagnosis of vitiligo treated using phototherapy at the National Skin Center, Singapore, over a 5\u2010year period. Seventy\u2010one Asian patients ages 5 to 15 years when they underwent phototherapy were identified. There was a higher proportion of Indian patients in our cohort than in the population. The duration of disease ranged from 2\u00a0months to 12\u00a0years. More than half of the patients had generalized vitiligo and more than one\u2010third had segmental vitiligo. Patients with generalized vitiligo had a better response than those with segmental vitiligo. Reported response rates were highest for narrowband ultraviolet B (<jats:styled-content style=\"fixed-case\">UVB<\/jats:styled-content>) phototherapy, followed by targeted phototherapy combining ultraviolet A1 (<jats:styled-content style=\"fixed-case\">UVA<\/jats:styled-content>1) and <jats:styled-content style=\"fixed-case\">UVB<\/jats:styled-content>; 308\u2010nm excimer lamp phototherapy and paint psoralen\u2013UVA photochemotherapy had marginally lower reported response rates. The duration of treatment ranged from 3 to 40\u00a0months and the total number of treatments ranged from 20 to 209 sessions. Reported side effects were mild and included itching, scaling, erythema, pain, sunburn, blistering, and phototoxicity. We consider phototherapy to be a safe and efficacious modality for the treatment of vitiligo in Asian children.<\/jats:p>","DOI":"10.1111\/pde.12506","type":"journal-article","created":{"date-parts":[[2015,1,30]],"date-time":"2015-01-30T07:49:11Z","timestamp":1422604151000},"page":"192-197","source":"Crossref","is-referenced-by-count":31,"title":["Phototherapy for the Treatment of Vitiligo in Asian Children"],"prefix":"10.1111","volume":"32","author":[{"given":"Mark Jean\u2010Aan","family":"Koh","sequence":"first","affiliation":[{"name":"Dermatology Service KK Women's &amp; Children's Hospital Singapore"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Zhun\u2010Rui","family":"Mok","sequence":"additional","affiliation":[{"name":"Department of Medicine National University Health System Singapore"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Wei\u2010Sheng","family":"Chong","sequence":"additional","affiliation":[{"name":"National Skin Center Singapore"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2015,1,30]]},"reference":[{"key":"e_1_2_7_2_1","doi-asserted-by":"publisher","DOI":"10.1001\/archderm.1977.01640010049006"},{"key":"e_1_2_7_3_1","doi-asserted-by":"publisher","DOI":"10.1034\/j.1600-0749.2003.00032.x"},{"key":"e_1_2_7_4_1","doi-asserted-by":"publisher","DOI":"10.1186\/1471-5945-6-3"},{"key":"e_1_2_7_5_1","doi-asserted-by":"publisher","DOI":"10.1159\/000348388"},{"key":"e_1_2_7_6_1","doi-asserted-by":"publisher","DOI":"10.1348\/000711299160077"},{"key":"e_1_2_7_7_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1468-3083.2009.03452.x"},{"key":"e_1_2_7_8_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2133.2011.10351.x"},{"key":"e_1_2_7_9_1","first-page":"e52","article-title":"The effect of combined calcipotriol and betamethasone dipropionate ointment in the treatment of vitiligo: an open, uncontrolled trial","volume":"11","author":"Xing C","year":"2012","journal-title":"J Drugs Dermatol"},{"key":"e_1_2_7_10_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1440-0960.2010.00701.x"},{"key":"e_1_2_7_11_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1525-1470.2011.01683.x"},{"key":"e_1_2_7_12_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaad.2008.07.053"},{"key":"e_1_2_7_13_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-4632.2004.02329.x"},{"key":"e_1_2_7_14_1","first-page":"13","article-title":"Using a 308\u2010nm excimer laser to treat vitiligo in Asians","volume":"18","author":"Al\u2010Otaibi SR","year":"2009","journal-title":"Acta Dermatovenerol Alp Panonica Adriat"},{"key":"e_1_2_7_15_1","doi-asserted-by":"publisher","DOI":"10.3346\/jkms.2005.20.2.273"},{"key":"e_1_2_7_16_1","doi-asserted-by":"publisher","DOI":"10.1111\/1523-1747.ep12480997"},{"key":"e_1_2_7_17_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0781.2006.00222.x"},{"key":"e_1_2_7_18_1","doi-asserted-by":"publisher","DOI":"10.1080\/09546630802155057"}],"container-title":["Pediatric Dermatology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fpde.12506","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/pde.12506","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,29]],"date-time":"2023-09-29T14:08:27Z","timestamp":1695996507000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/pde.12506"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2015,1,30]]},"references-count":17,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2015,3]]}},"alternative-id":["10.1111\/pde.12506"],"URL":"https:\/\/doi.org\/10.1111\/pde.12506","archive":["Portico"],"relation":{},"ISSN":["0736-8046","1525-1470"],"issn-type":[{"value":"0736-8046","type":"print"},{"value":"1525-1470","type":"electronic"}],"subject":[],"published":{"date-parts":[[2015,1,30]]}}}