{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,18]],"date-time":"2026-03-18T12:09:43Z","timestamp":1773835783844,"version":"3.50.1"},"reference-count":4,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2015,3,5]],"date-time":"2015-03-05T00:00:00Z","timestamp":1425513600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Pediatric Dermatology"],"published-print":{"date-parts":[[2015,5]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Hypertrophic lichen planus (<jats:styled-content style=\"fixed-case\">HLP<\/jats:styled-content>) is a T\u2010cell\u2010mediated process typically presenting with hypertrophic or verrucous plaques on the lower limbs. We report the case of a 24\u2010year\u2010old woman with a history of <jats:styled-content style=\"fixed-case\">HLP<\/jats:styled-content> since age 3 years presenting with rapid malignant transformation of one lesion into a large squamous cell carcinoma (<jats:styled-content style=\"fixed-case\">SCC<\/jats:styled-content>). Subsequent examination revealed progressive, widespread metastatic involvement, and the patient ultimately died from her disease. <jats:styled-content style=\"fixed-case\">SCC<\/jats:styled-content> associated with <jats:styled-content style=\"fixed-case\">HLP<\/jats:styled-content> is rare, with a review of the literature revealing fewer than 50 cases. This case highlights the need to be aware of suspicious changes in <jats:styled-content style=\"fixed-case\">HLP<\/jats:styled-content> and to educate patients as to when to be reevaluated.<\/jats:p>","DOI":"10.1111\/pde.12549","type":"journal-article","created":{"date-parts":[[2015,3,5]],"date-time":"2015-03-05T07:38:57Z","timestamp":1425541137000},"source":"Crossref","is-referenced-by-count":11,"title":["Widely Metastatic Squamous Cell Carcinoma Originating from Malignant Transformation of Hypertrophic Lichen Planus in a 24\u2010Year\u2010Old Woman: Case Report and Review of the Literature"],"prefix":"10.1111","volume":"32","author":[{"given":"Lana X.","family":"Tong","sequence":"first","affiliation":[{"name":"David Geffen School of Medicine University of California at Los Angeles Los Angeles California"},{"name":"Department of Health Policy and Management School of Public Health Harvard University Boston Massachusetts"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Matthew J.","family":"Weinstock","sequence":"additional","affiliation":[{"name":"Department of Hematology\/Oncology Beth Israel Deaconess Medical Center Harvard Medical School Boston Massachusetts"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Reed","family":"Drews","sequence":"additional","affiliation":[{"name":"Department of Hematology\/Oncology Beth Israel Deaconess Medical Center Harvard Medical School Boston Massachusetts"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yuri","family":"Sheikine","sequence":"additional","affiliation":[{"name":"Department of Pathology Beth Israel Deaconess Medical Center Harvard Medical School Boston Massachusetts"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Caroline C.","family":"Kim","sequence":"additional","affiliation":[{"name":"Department of Dermatology Beth Israel Deaconess Medical Center Harvard Medical School Boston Massachusetts"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2015,3,5]]},"reference":[{"key":"e_1_2_4_2_1","doi-asserted-by":"publisher","DOI":"10.1001\/archotol.1985.00800100091015"},{"key":"e_1_2_4_3_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1468-3083.2006.01500.x"},{"key":"e_1_2_4_4_1","first-page":"394","article-title":"[Squamous epithelial cancer in\u00a0lichen ruber hypertrophicus\u2014a case report with a\u00a0review of the literature]","volume":"61","author":"Bonnekoh B","year":"1986","journal-title":"Z Hautkr"},{"key":"e_1_2_4_5_1","doi-asserted-by":"crossref","first-page":"10","DOI":"10.5070\/D39CF3Q2FK","article-title":"Metastatic cutaneous squamous cell carcinoma arising from a previous area of chronic hypertrophic lichen planus","volume":"9","author":"Ardabili M","year":"2003","journal-title":"Dermatol Online J"}],"container-title":["Pediatric Dermatology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fpde.12549","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/pde.12549","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,1]],"date-time":"2023-10-01T13:05:04Z","timestamp":1696165504000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/pde.12549"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2015,3,5]]},"references-count":4,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2015,5]]}},"alternative-id":["10.1111\/pde.12549"],"URL":"https:\/\/doi.org\/10.1111\/pde.12549","archive":["Portico"],"relation":{},"ISSN":["0736-8046","1525-1470"],"issn-type":[{"value":"0736-8046","type":"print"},{"value":"1525-1470","type":"electronic"}],"subject":[],"published":{"date-parts":[[2015,3,5]]}}}