{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,7]],"date-time":"2026-10-07T07:06:09Z","timestamp":1791356769326,"version":"4.3.1"},"reference-count":54,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2015,3,26]],"date-time":"2015-03-26T00:00:00Z","timestamp":1427328000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Pediatric Dermatology"],"published-print":{"date-parts":[[2015,9]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>\n                    Pityriasis lichenoides (\n                    <jats:styled-content style=\"fixed-case\">PL<\/jats:styled-content>\n                    ) is a skin condition of unclear etiology that occurs not uncommonly in childhood. It is often classified into the acute form, pityriasis lichenoides et varioliformis acuta (\n                    <jats:styled-content style=\"fixed-case\">PLEVA<\/jats:styled-content>\n                    ), and the chronic form, pityriasis lichenoides chronica (\n                    <jats:styled-content style=\"fixed-case\">PLC<\/jats:styled-content>\n                    ). We performed a comprehensive review of the English\u2010language literature using the PubMed database of all cases of childhood\n                    <jats:styled-content style=\"fixed-case\">PL<\/jats:styled-content>\n                    reported from 1962 to 2014 and summarized the epidemiology, clinical features, treatment options, and prognosis of this condition in children. The proposed etiologies are discussed, including its association with infectious agents, medications, and immunizations and evidence for\n                    <jats:styled-content style=\"fixed-case\">PL<\/jats:styled-content>\n                    as a lymphoproliferative disorder. We found an average age of\n                    <jats:styled-content style=\"fixed-case\">PL<\/jats:styled-content>\n                    onset of 6.5\u00a0years, with a slight (61%) male predominance. We also found that\n                    <jats:styled-content style=\"fixed-case\">PLEVA<\/jats:styled-content>\n                    and\n                    <jats:styled-content style=\"fixed-case\">PLC<\/jats:styled-content>\n                    tend to occur with equal frequency and that, in many cases, there is clinical and histopathologic overlap between the two phenotypes. When systemic therapy is indicated, we propose that oral erythromycin and narrowband ultraviolet B phototherapy should be first\u2010line treatment options for children with\n                    <jats:styled-content style=\"fixed-case\">PL<\/jats:styled-content>\n                    since they have been shown to be effective and well tolerated. In most cases,\n                    <jats:styled-content style=\"fixed-case\">PL<\/jats:styled-content>\n                    follows a benign course with no greater risk of cutaneous T\u2010cell lymphoma, although given the rare case reports of transformation, long\u2010term follow\u2010up of these patients is recommended.\n                  <\/jats:p>","DOI":"10.1111\/pde.12581","type":"journal-article","created":{"date-parts":[[2015,3,27]],"date-time":"2015-03-27T18:10:39Z","timestamp":1427479839000},"page":"579-592","source":"Crossref","is-referenced-by-count":60,"title":["Pityriasis Lichenoides in Childhood: Review of Clinical Presentation and Treatment Options"],"prefix":"10.1111","volume":"32","author":[{"given":"Lauren","family":"Geller","sequence":"first","affiliation":[{"name":"Department of Dermatology Icahn School of Medicine at Mount Sinai  New York New York"},{"name":"Department of Pediatrics Icahn School of Medicine at Mount Sinai New York New 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