{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,28]],"date-time":"2025-10-28T05:51:59Z","timestamp":1761630719048},"reference-count":15,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2015,4,27]],"date-time":"2015-04-27T00:00:00Z","timestamp":1430092800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Pediatric Dermatology"],"published-print":{"date-parts":[[2015,7]]},"abstract":"Abstract<\/jats:title>Oral retinoids are being increasingly used to treat ichthyotic disorders in children. We report on two children with ichthyotic disorders who developed unusual manifestations after they were started on oral retinoids. The first case is a 10\u2010year\u2010old girl with nonbullous ichthyosiform erythroderma and the second is a 2\u2010year\u2010old girl with lamellar ichthyosis. The child with ichthyosiform erythroderma developed features of rickets within months of initiation of systemic retinoids. Her baseline examination before initiation of oral retinoids was normal. The second patient with lamellar ichthyosis was found to have low vitamin D<\/jats:styled-content> levels after 6\u00a0months of retinoid therapy, and prompt supplementation reversed the levels in 2\u00a0months. These cases are being reported to bring attention to the probable need for initiation of vitamin D<\/jats:styled-content> supplementation with systemic retinoid therapy in ichthyotic disorders in children.<\/jats:p>","DOI":"10.1111\/pde.12614","type":"journal-article","created":{"date-parts":[[2015,4,27]],"date-time":"2015-04-27T12:23:29Z","timestamp":1430137409000},"source":"Crossref","is-referenced-by-count":23,"title":["Vitamin D Deficiency After Oral Retinoid Therapy for Ichthyosis"],"prefix":"10.1111","volume":"32","author":[{"given":"Shekhar","family":"Neema","sequence":"first","affiliation":[{"name":"Department of Dermatology Command Hospital Kolkatta India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sweta","family":"Mukherjee","sequence":"additional","affiliation":[{"name":"Department of Pediatrics Command Hospital Kolkatta India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Biju","family":"Vasudevan","sequence":"additional","affiliation":[{"name":"Department of Dermatology Command Hospital Pune India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rajesh","family":"Verma","sequence":"additional","affiliation":[{"name":"Department of Dermatology Command Hospital Pune India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nikhil","family":"Moorchung","sequence":"additional","affiliation":[{"name":"Department of Pathology Armed Forces Medical College Pune India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Manas","family":"Chatterjee","sequence":"additional","affiliation":[{"name":"Department of Dermatology Command Hospital Kolkatta India"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2015,4,27]]},"reference":[{"key":"e_1_2_4_2_1","doi-asserted-by":"crossref","first-page":"1023","DOI":"10.1046\/j.1365-2133.1996.d01-895.x","article-title":"An appraisal of acitretin therapy in children with inherited disorder of keratinization","volume":"134","author":"Lacour M","year":"1996","journal-title":"Br J Dermatol"},{"key":"e_1_2_4_3_1","doi-asserted-by":"publisher","DOI":"10.1093\/tropej\/49.4.201"},{"key":"e_1_2_4_4_1","doi-asserted-by":"publisher","DOI":"10.1093\/ajcn\/80.6.1725S"},{"key":"e_1_2_4_5_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2133.2011.10672.x"},{"key":"e_1_2_4_6_1","doi-asserted-by":"publisher","DOI":"10.4103\/0022-3859.33872"},{"key":"e_1_2_4_7_1","doi-asserted-by":"publisher","DOI":"10.4103\/0378-6323.25641"},{"key":"e_1_2_4_8_1","doi-asserted-by":"crossref","first-page":"648","DOI":"10.1001\/archderm.1993.01680260120024","article-title":"Secondary hyperparathyroidism in patients with ichthyosis is not caused by vitamin D deficiency or ingestion of retinoids","volume":"129","author":"Milstone LM","year":"1993","journal-title":"Arch Dermatol"},{"key":"e_1_2_4_9_1","doi-asserted-by":"publisher","DOI":"10.1097\/00005176-200402000-00012"},{"key":"e_1_2_4_10_1","doi-asserted-by":"publisher","DOI":"10.1359\/jbmr.1998.13.3.325"},{"key":"e_1_2_4_11_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00198-003-1577-y"},{"key":"e_1_2_4_12_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa021171"},{"key":"e_1_2_4_13_1","doi-asserted-by":"publisher","DOI":"10.1007\/BF01405299"},{"key":"e_1_2_4_14_1","doi-asserted-by":"publisher","DOI":"10.1016\/8756-3282(90)90072-7"},{"key":"e_1_2_4_15_1","doi-asserted-by":"publisher","DOI":"10.1080\/000155598441837"},{"key":"e_1_2_4_16_1","doi-asserted-by":"publisher","DOI":"10.1006\/bbrc.1996.1903"}],"container-title":["Pediatric Dermatology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fpde.12614","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/pde.12614","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,29]],"date-time":"2023-09-29T22:13:15Z","timestamp":1696025595000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/pde.12614"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2015,4,27]]},"references-count":15,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2015,7]]}},"alternative-id":["10.1111\/pde.12614"],"URL":"https:\/\/doi.org\/10.1111\/pde.12614","archive":["Portico"],"relation":{},"ISSN":["0736-8046","1525-1470"],"issn-type":[{"value":"0736-8046","type":"print"},{"value":"1525-1470","type":"electronic"}],"subject":[],"published":{"date-parts":[[2015,4,27]]}}}