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Studies have shown that skin piercings and other nickel\u2010laden exposures can trigger the onset of nickel <jats:styled-content style=\"fixed-case\">ACD<\/jats:styled-content> in those who are susceptible. Nickel <jats:styled-content style=\"fixed-case\">ACD<\/jats:styled-content> causes a vast amount of cutaneous disease in children. Cases of nickel <jats:styled-content style=\"fixed-case\">ACD<\/jats:styled-content> in children have been reported in peer\u2010reviewed literature from 28 states. Common items that contain inciting nickel include jewelry, coins, zippers, belts, tools, toys, chair studs, cases for cell phones and tablets, and dental appliances. The diagnosis of nickel <jats:styled-content style=\"fixed-case\">ACD<\/jats:styled-content> has been routinely confirmed by patch testing in children older than 6\u00a0months suspected of <jats:styled-content style=\"fixed-case\">ACD<\/jats:styled-content> from nickel. Unlike in Europe, there are no mandatory restrictions legislated for nickel exposure in the United States. Denmark has demonstrated that regulation of the nickel content in metals can lower the risk of <jats:styled-content style=\"fixed-case\">ACD<\/jats:styled-content> and the associated health care\u2013related costs that arise from excess nickel exposure. To further awareness, this article reviews the prominent role of nickel in pediatric skin disease in the United States. It discusses the need for a campaign by caretakers to reduce nickel\u2010related morbidity. Lastly, it promotes the model of European legislation as a successful intervention in the prevention of nickel <jats:styled-content style=\"fixed-case\">ACD<\/jats:styled-content>.<\/jats:p>","DOI":"10.1111\/pde.12639","type":"journal-article","created":{"date-parts":[[2015,7,27]],"date-time":"2015-07-27T07:49:41Z","timestamp":1437983381000},"page":"779-785","source":"Crossref","is-referenced-by-count":45,"title":["Nickel Allergy and Our Children's Health: A Review of Indexed Cases and a View of Future Prevention"],"prefix":"10.1111","volume":"32","author":[{"given":"Sharon E.","family":"Jacob","sequence":"first","affiliation":[{"name":"Loma Linda University Loma Linda California"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8397-6727","authenticated-orcid":false,"given":"Alina","family":"Goldenberg","sequence":"additional","affiliation":[{"name":"University of California at San Diego San Diego California"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Janice L.","family":"Pelletier","sequence":"additional","affiliation":[{"name":"Eastern Maine Medical Center Bangor Maine"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Luz S.","family":"Fonacier","sequence":"additional","affiliation":[{"name":"Department of Clinical Medicine State University of New York at Stony Brook Stony Brook New York"},{"name":"Allergy and Immunology Training Program Winthrop University Hospital Mineola New York"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Richard","family":"Usatine","sequence":"additional","affiliation":[{"name":"University of Texas Health Science Center San Antonio Texas"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nanette","family":"Silverberg","sequence":"additional","affiliation":[{"name":"Icahn School of Medicine at Mt.\u00a0Sinai Mt. 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