{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,27]],"date-time":"2026-02-27T20:21:04Z","timestamp":1772223664558,"version":"3.50.1"},"reference-count":6,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2015,9,4]],"date-time":"2015-09-04T00:00:00Z","timestamp":1441324800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Pediatric Dermatology"],"published-print":{"date-parts":[[2015,11]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Propylene glycol is a well\u2010documented causative agent of allergic contact dermatitis (<jats:styled-content style=\"fixed-case\">ACD<\/jats:styled-content>). It is also reported to cause systemic dermatitis after ingestion of foods or medicines containing it and after intravenous injection of a medicine with propylene glycol in its base. We describe two adolescents with sensitivity to propylene glycol confirmed by patch testing whose dermatitis improved dramatically after cessation of oral antihistamines containing propylene glycol. We report these cases to alert providers to the potential for worsening of <jats:styled-content style=\"fixed-case\">ACD<\/jats:styled-content> due to systemic exposure to propylene glycol in patients with a cutaneous sensitivity to the allergen.<\/jats:p>","DOI":"10.1111\/pde.12668","type":"journal-article","created":{"date-parts":[[2015,9,18]],"date-time":"2015-09-18T18:09:35Z","timestamp":1442599775000},"source":"Crossref","is-referenced-by-count":15,"title":["Excipients in Oral Antihistamines Can Perpetuate Allergic Contact Dermatitis"],"prefix":"10.1111","volume":"32","author":[{"given":"Elizabeth M.","family":"Tocci","sequence":"first","affiliation":[{"name":"University of Massachusetts Medical School Worcester Massachusetts"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Amanda","family":"Robinson","sequence":"additional","affiliation":[{"name":"Division of Dermatology Department of Medicine UMass Memorial Worcester Massachusetts"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Leah","family":"Belazarian","sequence":"additional","affiliation":[{"name":"Division of Dermatology Department of Medicine UMass Memorial Worcester Massachusetts"},{"name":"Department of Pediatrics University of Massachusetts Medical School Worcester Massachusetts"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Elizabeth","family":"Foley","sequence":"additional","affiliation":[{"name":"Division of Dermatology Department of Medicine UMass Memorial Worcester Massachusetts"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Karen","family":"Wiss","sequence":"additional","affiliation":[{"name":"Division of Dermatology Department of Medicine UMass Memorial Worcester Massachusetts"},{"name":"Department of Pediatrics University of Massachusetts Medical School Worcester Massachusetts"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Dianne L.","family":"Silvestri","sequence":"additional","affiliation":[{"name":"Division of Dermatology Department of Medicine UMass Memorial Worcester Massachusetts"},{"name":"Contact\u00a0Dermatitis Referral Clinic Worcester Massachusetts"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2015,9,4]]},"reference":[{"key":"e_1_2_4_2_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1525-1470.2008.00769.x"},{"key":"e_1_2_4_3_1","doi-asserted-by":"crossref","first-page":"105","DOI":"10.2310\/6620.2008.07037","article-title":"Systemic contact dermatitis from propylene glycol","volume":"19","author":"Lowther A","year":"2008","journal-title":"Dermatitis"},{"key":"e_1_2_4_4_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0536.1978.tb03719.x"},{"key":"e_1_2_4_5_1","first-page":"327","article-title":"Systemic contact dermatitis to intravenous Valium in a person sensitive to propylene glycol","volume":"55","author":"Fisher AA","year":"1995","journal-title":"Cutis"},{"key":"e_1_2_4_6_1","doi-asserted-by":"publisher","DOI":"10.1097\/DER.0000000000000028"},{"key":"e_1_2_4_7_1","doi-asserted-by":"publisher","DOI":"10.1097\/DER.0b013e31827658ed"}],"container-title":["Pediatric Dermatology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fpde.12668","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/pde.12668","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,24]],"date-time":"2023-09-24T15:08:11Z","timestamp":1695568091000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/pde.12668"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2015,9,4]]},"references-count":6,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2015,11]]}},"alternative-id":["10.1111\/pde.12668"],"URL":"https:\/\/doi.org\/10.1111\/pde.12668","archive":["Portico"],"relation":{},"ISSN":["0736-8046","1525-1470"],"issn-type":[{"value":"0736-8046","type":"print"},{"value":"1525-1470","type":"electronic"}],"subject":[],"published":{"date-parts":[[2015,9,4]]}}}