{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,18]],"date-time":"2026-08-18T15:52:09Z","timestamp":1787068329715,"version":"build-2736575974"},"reference-count":21,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2015,11,26]],"date-time":"2015-11-26T00:00:00Z","timestamp":1448496000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Pediatric Dermatology"],"published-print":{"date-parts":[[2016,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Objectives<\/jats:title>\n                    <jats:p>The objectives of the study were to evaluate and compare medication adherence associated with acne drugs in children and adolescents with acne vulgaris.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>Data from MarketScan Medicaid enrollees with acne vulgaris were included if patients were ages 6 to 17 years on the index date, had at least one acne\u2010related medication claim, and were enrolled in Medicaid during January 2004 to December 2007. The adherence rate was measured using the medication possession ratio. The medication possession ratio was dichotomized to categorize patients as adherent (\u22650.8) or nonadherent (&lt;0.8). Multivariate logistic regressions were used for analyses of the medication possession ratio.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Of 20,039 eligible patients, 2,860 patients were children and 17,179 patients were adolescent. Approximately 6.96% of children and 16.75% of adolescents had at least one acne\u2010related medication refill. The mean adherence rate to acne medication was significantly different between children (0.22) and adolescents (0.32). In addition, only 3.71% of children were adherent to acne medication while 13.38% of adolescents were adherent. After controlling for covariates, adolescents were 2.06 times more likely to get an acne\u2010related medication refilled and were 2.40 times more likely to be adherent to acne\u2010related medication. The analyses also showed that acne\u2010related medication adherence was associated with the patient's characteristics and acne medication type.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>Neither patient population was considered adherent to acne\u2010related medications, nor was there a significant difference between the two patient populations. This study also revealed that medication type is a contributing factor towards adherence. Health care providers should strive to educate patients on the importance of medication adherence.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/pde.12713","type":"journal-article","created":{"date-parts":[[2015,11,26]],"date-time":"2015-11-26T05:26:00Z","timestamp":1448515560000},"page":"49-55","source":"Crossref","is-referenced-by-count":17,"title":["Medication Adherence in Children and Adolescents with Acne Vulgaris in Medicaid: A Retrospective Study Analysis"],"prefix":"10.1111","volume":"33","author":[{"given":"Chloe","family":"Hester","sequence":"first","affiliation":[{"name":"Sentara Healthcare Norfolk Virginia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chanhyun","family":"Park","sequence":"additional","affiliation":[{"name":"Pharmacy Practice &amp; Health Outcomes University of Texas Austin Texas"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Janice","family":"Chung","sequence":"additional","affiliation":[{"name":"Healthcore Wilmington DE"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rajesh","family":"Balkrishnan","sequence":"additional","affiliation":[{"name":"Public Health Sciences University of Virginia Charlottesville Virginia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Steven","family":"Feldman","sequence":"additional","affiliation":[{"name":"Dermatology Wake Forest Baptist Health Winston\u2010Salem North Carolina"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jongwha","family":"Chang","sequence":"additional","affiliation":[{"name":"Pharmaceutical, Social &amp; Administrative Sciences Samford University Birmingham Alabama"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2015,11,26]]},"reference":[{"key":"e_1_2_6_2_1","first-page":"1555","volume-title":"Pharmacotherapy: a pathophysiologic approach","author":"Sibbald D","year":"2014"},{"key":"e_1_2_6_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaad.2006.05.048"},{"key":"e_1_2_6_4_1","doi-asserted-by":"publisher","DOI":"10.1159\/000067817"},{"key":"e_1_2_6_5_1","doi-asserted-by":"publisher","DOI":"10.1001\/archderm.1994.01690030040006"},{"key":"e_1_2_6_6_1","first-page":"94","article-title":"Acne vulgaris in the United States: a descriptive epidemiology","volume":"86","author":"Yentzer BA","year":"2010","journal-title":"Cutis"},{"key":"e_1_2_6_7_1","first-page":"32","article-title":"Over\u2010the\u2010counter acne treatments: a review","volume":"5","author":"Decker A","year":"2012","journal-title":"J Clin Aesthet Dermatol"},{"key":"e_1_2_6_8_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1525-1470.2011.01493.x"},{"key":"e_1_2_6_9_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1525-1470.2009.00932.x"},{"key":"e_1_2_6_10_1","doi-asserted-by":"publisher","DOI":"10.1007\/s40257-013-0016-x"},{"key":"e_1_2_6_11_1","unstructured":"Division of Human Development and Disabilities National Center on Birth Defects and Developmental Disabilities Centers for Disease Control and Prevention. 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