{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,4,9]],"date-time":"2025-04-09T11:32:10Z","timestamp":1744198330758},"reference-count":16,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2015,12,8]],"date-time":"2015-12-08T00:00:00Z","timestamp":1449532800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Pediatric Dermatology"],"published-print":{"date-parts":[[2016,1]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>Patients with moderate to severe atopic dermatitis (AD) often have a concurrent diagnosis of contact dermatitis, but patch testing in these patients presents a unique set of challenges. Barrier impairment and <jats:italic>Staphylococcus aureus<\/jats:italic> colonization and infection, along with the sealed occlusion that takes place during the patch testing procedure, can create an optimal environment for bacterial overgrowth.<\/jats:p><\/jats:sec><jats:sec><jats:title>Aims<\/jats:title><jats:p>To identify patients at risk for <jats:italic>S. aureus<\/jats:italic> overgrowth during patch testing and provide pre\u2010 and peripatch testing interventions to aid clinicians in obtaining the best possible patch test results in this complicated population.<\/jats:p><\/jats:sec><jats:sec><jats:title>Materials and Methods<\/jats:title><jats:p>A retrospective review was performed of five patients with moderate to severe AD for which <jats:italic>S. aureus<\/jats:italic> overgrowth and superinfection complicated patch test evaluation.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>All five patients were able to complete the patch test procedure and all had relevant positive patch test reactions. Complications during patch testing included erythema, oozing, foul odor under the patches, and purulent material at the patch sites. One patient had a culture performed during patch testing that showed methicillin\u2010sensitive <jats:italic>S. aureus<\/jats:italic>.<\/jats:p><\/jats:sec><jats:sec><jats:title>Discussion<\/jats:title><jats:p>Patch testing can play an important role in the examination and management of patients with refractory AD.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Moderate to severe AD and concern regarding <jats:italic>S. aureus<\/jats:italic> overgrowth should not preclude patch testing.<\/jats:p><\/jats:sec>","DOI":"10.1111\/pde.12723","type":"journal-article","created":{"date-parts":[[2015,12,9]],"date-time":"2015-12-09T13:36:20Z","timestamp":1449668180000},"page":"56-61","source":"Crossref","is-referenced-by-count":7,"title":["Countering Staphylococcus Overgrowth During Patch Testing in Children with Moderate to Severe Atopic Dermatitis"],"prefix":"10.1111","volume":"33","author":[{"given":"Shehla","family":"Admani","sequence":"first","affiliation":[{"name":"Department of Dermatology University of California at San Diego San Diego California"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Catalina","family":"Matiz","sequence":"additional","affiliation":[{"name":"Department of Dermatology Rady Children's Hospital San Diego University of California, San Diego San Diego California"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sharon E.","family":"Jacob","sequence":"additional","affiliation":[{"name":"Department of Dermatology Loma Linda University Loma Linda California"},{"name":"Contact Dermatitis Clinic Loma Linda University Loma Linda California"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2015,12,8]]},"reference":[{"key":"e_1_2_5_2_1","doi-asserted-by":"publisher","DOI":"10.1097\/DER.0000000000000037"},{"key":"e_1_2_5_3_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1399-3038.2004.00182.x"},{"key":"e_1_2_5_4_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1365-4362.1997.00290.x"},{"key":"e_1_2_5_5_1","doi-asserted-by":"publisher","DOI":"10.1007\/978-3-662-10302-9_21"},{"key":"e_1_2_5_6_1","doi-asserted-by":"crossref","first-page":"701","DOI":"10.1111\/j.1610-0387.2011.07707.x","article-title":"Exacerbation of atopic dermatitis upon alkaline skin care","volume":"9","author":"Butzmann CM","year":"2011","journal-title":"J Dtsch Dermatol Ges"},{"key":"e_1_2_5_7_1","doi-asserted-by":"publisher","DOI":"10.1007\/s40257-013-0033-9"},{"key":"e_1_2_5_8_1","doi-asserted-by":"publisher","DOI":"10.1542\/peds.2008-2217"},{"key":"e_1_2_5_9_1","doi-asserted-by":"publisher","DOI":"10.1111\/pde.12150"},{"key":"e_1_2_5_10_1","doi-asserted-by":"publisher","DOI":"10.1111\/exd.12251"},{"key":"e_1_2_5_11_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1525-1470.2007.00589.x"},{"key":"e_1_2_5_12_1","doi-asserted-by":"publisher","DOI":"10.1001\/archinte.1996.00040041109010"},{"key":"e_1_2_5_13_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaad.2008.07.058"},{"key":"e_1_2_5_14_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaad.2014.04.045"},{"key":"e_1_2_5_15_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.0105-1873.2004.00340.x"},{"key":"e_1_2_5_16_1","doi-asserted-by":"publisher","DOI":"10.1001\/archderm.1986.01660210057018"},{"key":"e_1_2_5_17_1","doi-asserted-by":"publisher","DOI":"10.1111\/pde.12281"}],"container-title":["Pediatric Dermatology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fpde.12723","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/pde.12723","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,26]],"date-time":"2023-09-26T06:04:51Z","timestamp":1695708291000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/pde.12723"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2015,12,8]]},"references-count":16,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2016,1]]}},"alternative-id":["10.1111\/pde.12723"],"URL":"https:\/\/doi.org\/10.1111\/pde.12723","archive":["Portico"],"relation":{},"ISSN":["0736-8046","1525-1470"],"issn-type":[{"value":"0736-8046","type":"print"},{"value":"1525-1470","type":"electronic"}],"subject":[],"published":{"date-parts":[[2015,12,8]]}}}