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We describe successful rituximab therapy in a 4\u2010year\u2010old, the youngest patient with PV ever reported to receive rituximab. A live attenuated vaccination was later given without incident. We also review rituximab clinical outcomes, toxicity, dosing protocols, and relapse in children with PV.<\/jats:p>","DOI":"10.1111\/pde.12744","type":"journal-article","created":{"date-parts":[[2016,1,14]],"date-time":"2016-01-14T10:21:37Z","timestamp":1452766897000},"source":"Crossref","is-referenced-by-count":20,"title":["Rituximab Therapy for Childhood Pemphigus Vulgaris"],"prefix":"10.1111","volume":"33","author":[{"given":"Leah","family":"Kincaid","sequence":"first","affiliation":[{"name":"Division of Dermatology Department of Medicine University of Toronto Toronto Ontario Canada"},{"name":"Section of Dermatology Division of Pediatric Medicine Hospital for Sick Children Toronto Ontario Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Miriam","family":"Weinstein","sequence":"additional","affiliation":[{"name":"Division of Dermatology Department of Medicine University of Toronto Toronto Ontario Canada"},{"name":"Section of Dermatology Division of Pediatric Medicine Hospital for Sick Children Toronto Ontario Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2016,1,14]]},"reference":[{"key":"e_1_2_4_2_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1525-1470.2011.01514.x"},{"key":"e_1_2_4_3_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1749-6632.2009.04744.x"},{"key":"e_1_2_4_4_1","doi-asserted-by":"publisher","DOI":"10.1007\/s12016-007-8021-6"},{"key":"e_1_2_4_5_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1365-4362.1999.00764.x"},{"key":"e_1_2_4_6_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2133.2006.07646.x"},{"key":"e_1_2_4_7_1","doi-asserted-by":"publisher","DOI":"10.1097\/00001813-200211002-00002"},{"key":"e_1_2_4_8_1","first-page":"202","article-title":"Dermatologic rituximab dosing: treatment of refractory pemphigus vulgaris in an adolescent male","volume":"10","author":"Stephens JB","year":"2011","journal-title":"J Drugs Dermatol"},{"key":"e_1_2_4_9_1","doi-asserted-by":"publisher","DOI":"10.1586\/17469872.3.3.259"},{"key":"e_1_2_4_10_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1525-1470.2005.00118.x"},{"key":"e_1_2_4_11_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2133.2005.06740.x"},{"key":"e_1_2_4_12_1","first-page":"335","article-title":"Rituximab therapy in severe juvenile pemphigus vulgaris","volume":"80","author":"Mamelak AJ","year":"2007","journal-title":"Cutis"},{"key":"e_1_2_4_13_1","doi-asserted-by":"publisher","DOI":"10.1159\/000287254"},{"key":"e_1_2_4_14_1","doi-asserted-by":"publisher","DOI":"10.4103\/0378-6323.100587"},{"key":"e_1_2_4_15_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1468-3083.2011.04391.x"},{"key":"e_1_2_4_16_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaad.2011.12.019"},{"key":"e_1_2_4_17_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.pedneo.2013.08.008"},{"key":"e_1_2_4_18_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaad.2014.05.071"},{"key":"e_1_2_4_19_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1525-1470.2007.00369.x"},{"key":"e_1_2_4_20_1","doi-asserted-by":"publisher","DOI":"10.1111\/cei.12390"},{"key":"e_1_2_4_21_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaci.2011.08.008"}],"container-title":["Pediatric Dermatology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fpde.12744","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/pde.12744","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,24]],"date-time":"2023-09-24T07:02:28Z","timestamp":1695538948000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/pde.12744"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2016,1,14]]},"references-count":20,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2016,3]]}},"alternative-id":["10.1111\/pde.12744"],"URL":"https:\/\/doi.org\/10.1111\/pde.12744","archive":["Portico"],"relation":{},"ISSN":["0736-8046","1525-1470"],"issn-type":[{"value":"0736-8046","type":"print"},{"value":"1525-1470","type":"electronic"}],"subject":[],"published":{"date-parts":[[2016,1,14]]}}}