{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2023,9,25]],"date-time":"2023-09-25T06:15:23Z","timestamp":1695622523579},"reference-count":15,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2016,2,10]],"date-time":"2016-02-10T00:00:00Z","timestamp":1455062400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Pediatric Dermatology"],"published-print":{"date-parts":[[2016,3]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Chronic erosive pustular dermatitis with a predilection for the scalp is a hallmark of ectodermal dysplasias (<jats:styled-content style=\"fixed-case\">ED<\/jats:styled-content>s) caused by mutations in <jats:italic>TP<\/jats:italic><jats:italic>63<\/jats:italic>, including <jats:styled-content style=\"fixed-case\">R<\/jats:styled-content>app\u2013<jats:styled-content style=\"fixed-case\">H<\/jats:styled-content>odgkin and <jats:styled-content style=\"fixed-case\">H<\/jats:styled-content>ay\u2013<jats:styled-content style=\"fixed-case\">W<\/jats:styled-content>ells <jats:styled-content style=\"fixed-case\">ED<\/jats:styled-content>s. It is among the most troublesome and symptomatic complications and is typically refractory to classic wound care approaches. We report two cases of <jats:styled-content style=\"fixed-case\">R<\/jats:styled-content>app\u2013<jats:styled-content style=\"fixed-case\">H<\/jats:styled-content>odgkin <jats:styled-content style=\"fixed-case\">ED<\/jats:styled-content> with refractory scalp erosions that markedly improved with the use of potent topical steroids. We also note marked similarities between this scalp inflammation and \u201cerosive pustular dermatosis of the scalp,\u201d a condition more typically found in elderly individuals with severe scalp sun damage, and speculate about possible shared pathogenetic mechanisms.<\/jats:p>","DOI":"10.1111\/pde.12784","type":"journal-article","created":{"date-parts":[[2016,2,10]],"date-time":"2016-02-10T10:50:15Z","timestamp":1455101415000},"source":"Crossref","is-referenced-by-count":3,"title":["High\u2010Potency Topical Steroids: An Effective Therapy for Chronic Scalp Inflammation in Rapp\u2013Hodgkin Ectodermal Dysplasia"],"prefix":"10.1111","volume":"33","author":[{"given":"Martin","family":"Theiler","sequence":"first","affiliation":[{"name":"Department of Pediatric Dermatology University Children's Hospital Zurich Zurich Switzerland"},{"name":"Department of Dermatology University Hospital Zurich Zurich Switzerland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ilona J.","family":"Frieden","sequence":"additional","affiliation":[{"name":"Department of Dermatology and Pediatrics University of California, San Francisco San Francisco California"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2016,2,10]]},"reference":[{"key":"e_1_2_4_2_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2133.2010.09859.x"},{"key":"e_1_2_4_3_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1525-1470.1993.tb00394.x"},{"key":"e_1_2_4_4_1","doi-asserted-by":"publisher","DOI":"10.1002\/ajmg.a.32797"},{"key":"e_1_2_4_5_1","doi-asserted-by":"publisher","DOI":"10.1001\/archderm.141.12.1591"},{"key":"e_1_2_4_6_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2133.2012.10888.x"},{"key":"e_1_2_4_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaad.2005.05.038"},{"key":"e_1_2_4_8_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1525-1470.1986.tb00549.x"},{"key":"e_1_2_4_9_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2133.1979.tb05581.x"},{"key":"e_1_2_4_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaad.2007.04.026"},{"key":"e_1_2_4_11_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaad.2006.07.009"},{"key":"e_1_2_4_12_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1525-1470.2006.00304.x"},{"key":"e_1_2_4_13_1","doi-asserted-by":"publisher","DOI":"10.2340\/00015555-0802"},{"key":"e_1_2_4_14_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaad.2011.10.011"},{"key":"e_1_2_4_15_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaad.2011.05.008"},{"key":"e_1_2_4_16_1","doi-asserted-by":"publisher","DOI":"10.1684\/ejd.2015.2519"}],"container-title":["Pediatric Dermatology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fpde.12784","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/pde.12784","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,24]],"date-time":"2023-09-24T07:02:30Z","timestamp":1695538950000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/pde.12784"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2016,2,10]]},"references-count":15,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2016,3]]}},"alternative-id":["10.1111\/pde.12784"],"URL":"https:\/\/doi.org\/10.1111\/pde.12784","archive":["Portico"],"relation":{},"ISSN":["0736-8046","1525-1470"],"issn-type":[{"value":"0736-8046","type":"print"},{"value":"1525-1470","type":"electronic"}],"subject":[],"published":{"date-parts":[[2016,2,10]]}}}