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The product was well tolerated, with only two children presenting with eczema at the application site. These adverse reactions were considered unlikely to be related to the test product, because a patch test was negative in one of the individuals and the other event occurred in only one of the two treated areas. Nanorap is an efficacious and well\u2010tolerated option for topical anesthesia in children undergoing cryotherapy for <jats:styled-content style=\"fixed-case\">MC<\/jats:styled-content>.<\/jats:p>","DOI":"10.1111\/pde.12842","type":"journal-article","created":{"date-parts":[[2016,4,4]],"date-time":"2016-04-04T09:37:14Z","timestamp":1459762634000},"source":"Crossref","is-referenced-by-count":4,"title":["Tolerability of 2.5% Lidocaine\/Prilocaine Hydrogel in Children Undergoing Cryotherapy for Molluscum Contagiosum"],"prefix":"10.1111","volume":"33","author":[{"given":"Andr\u00e9 A.M.","family":"Gobbato","sequence":"first","affiliation":[{"name":"Department of Pharmacology Faculty of Medical Sciences State University of Campinas Sao Paulo Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tainah","family":"Babad\u00f3pulos","sequence":"additional","affiliation":[{"name":"Galeno Research Unit Campinas Sao Paulo Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Cintia A.R.S.","family":"Gobbato","sequence":"additional","affiliation":[{"name":"Department of Pharmacology Faculty of Medical Sciences State University of Campinas Sao Paulo Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ronilson A.","family":"Moreno","sequence":"additional","affiliation":[{"name":"Galeno Research Unit Campinas Sao Paulo Brazil"},{"name":"Faculty of Medical Sciences Metropolitan University of Santos Santos Sao Paulo Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Thiago","family":"Gagliano\u2010Juc\u00e1","sequence":"additional","affiliation":[{"name":"Institute of Biophysics Carlos Chagas Filho Federal University of Rio de Janeiro Rio de Janeiro Rio de Janeiro Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gilberto","family":"De Nucci","sequence":"additional","affiliation":[{"name":"Department of Pharmacology Faculty of Medical Sciences State University of Campinas Sao Paulo Brazil"},{"name":"Faculty of Medical Sciences Metropolitan University of Santos Santos Sao Paulo Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2016,4,4]]},"reference":[{"key":"e_1_2_5_2_1","doi-asserted-by":"publisher","DOI":"10.2310\/7750.2013.13133"},{"key":"e_1_2_5_3_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1525-1470.1998.tb01347.x"},{"key":"e_1_2_5_4_1","doi-asserted-by":"publisher","DOI":"10.1097\/FTD.0000000000000156"},{"key":"e_1_2_5_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/0304-3959(77)90036-7"},{"key":"e_1_2_5_6_1","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.301.6744.153"}],"container-title":["Pediatric Dermatology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fpde.12842","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/pde.12842","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,24]],"date-time":"2023-09-24T00:20:25Z","timestamp":1695514825000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/pde.12842"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2016,4,4]]},"references-count":5,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2016,5]]}},"alternative-id":["10.1111\/pde.12842"],"URL":"https:\/\/doi.org\/10.1111\/pde.12842","archive":["Portico"],"relation":{},"ISSN":["0736-8046","1525-1470"],"issn-type":[{"value":"0736-8046","type":"print"},{"value":"1525-1470","type":"electronic"}],"subject":[],"published":{"date-parts":[[2016,4,4]]}}}